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Journal Articles

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

Takashi Ishio, Joji Shimono, Sarvesh Kumar, Yuquan Lin, Emmanuel Bachy, Michael N. Petrus, Yandan Yang, Michiyuki Maeda, Hideki Goto, Satoshi Hashino, Takanori Teshima, MD, Thomas A. Waldmann, MD, Louis Staudt, MD, Masao Nakagawa

Blood (2019) 134 (Supplement_1): 3781.

https://doi.org/10.1182/blood-2019-124670

Published: 2019

Journal Articles

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Ursula S.A. Stalmann, MD, Fabio Ticconi, MSc, Ronghui Li, MSc, Aaron B. Wong, PhD, Glenn Cowley, PhD, David E. Root, PhD, Dirk Heckl, PhD, Inge Snoeren, MSc, Sergio Martinez, PhDMSc, Tim H Brümmendorf, MD, Andreas Schuppert, PhD, Ivan Costa, PhD, Benjamin L. Ebert, MD PhD, Rebekka K. Schneider, MD PhD

Blood (2019) 134 (Supplement_1): 559.

https://doi.org/10.1182/blood-2019-122588

Published: 2019

Journal Articles

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Alessandro Lagana, PhD, Seongjee Park, Donna Edwards, Violetta Leshchenko, PhD, Marsha Crochiere, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2018) 132 (Supplement 1): 3216.

https://doi.org/10.1182/blood-2018-99-116500

Published: 2018

Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Blood (2018) 132 (Supplement 1): 55.

https://doi.org/10.1182/blood-2018-99-113916

Published: 2018

Journal Articles

In Vivo Genome-Wide Crispr Library Screen in a Xenograft Mouse Model of Tumor Growth and Metastasis of Multiple Myeloma

Yujia Shen, PhD, Salomon Manier, MD, Jihye Park, PhD, Yuji Mishima, PhD, Marzia Capelletti, PhD MMSc, Aldo M. Roccaro, MD PhD, Daisy Huynh, BS, MS, Antonio Sacco, BS, Sabrin Tahri, BS, Glenn Cowley, PhD, John G Doench, PhD, David Root, PhD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 1137.

https://doi.org/10.1182/blood.V128.22.1137.1137

Published: 2016

Journal Articles

EZH2 Enables the Proliferation of Germinal Center B Cells and DLBCL through a Rb-E2F1 Positive Feedback Loop Involving Repression of CDKN1A

Wendy Béguelin, PhD, Martin A Rivas, PhD, María Teresa Calvo Fernández, Ari Melnick, MD

Blood (2016) 128 (22): 734.

https://doi.org/10.1182/blood.V128.22.734.734

Published: 2016

Journal Articles

Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo

Blood (2016) 128 (22): 745.

https://doi.org/10.1182/blood.V128.22.745.745

Published: 2016

Journal Articles

Discovery and Characterization of Promoter and Super-Enhancer-Associated Dependencies through E2F and BET Bromodomains in Multiple Myeloma

Mariateresa Fulciniti, Charles Y. Lin, Mehmet K Samur, PhD, Matthew Lawlor, Kenneth C Anderson, James E. Bradner, MD, Nikhil C. Munshi, MD

Blood (2015) 126 (23): 838.

https://doi.org/10.1182/blood.V126.23.838.838

Published: 2015

Journal Articles

Proliferation-Independent Functions of the E2F-2 Transcription Factor during Terminal Erythroid Maturation

Kelsey Swartz, Gangjian Qin, MD, Alexander C Minella, MD

Blood (2014) 124 (21): 4356.

https://doi.org/10.1182/blood.V124.21.4356.4356

Published: 2014

Journal Articles

Atypical E2F Dependent Dysregulation Of Cell Cycling By Microrna-142 Regulates T-Cell Responses and Experimental Graft-Versus-Host Disease

Yaping Sun, M.D., Ph.D, Kay Oravecz-Wilson, PhD, Thomas Saunders, PhD, Ying Wang, MD, Tomomi Toubai, MD, PhD, Nathan Mathewson, BS, Chen Liu, MD. PhD, Guoqing Hou, PhD, Emily Cummings, BS, Charles Ross, MD, Pavan Reddy, MD

Blood (2013) 122 (21): 136.

https://doi.org/10.1182/blood.V122.21.136.136

Published: 2013

Journal Articles

A new twist to the GATA switch

Sjaak Philipsen

Blood (2013) 122 (20): 3391–3392.

https://doi.org/10.1182/blood-2013-09-527606

Published: 2013

Journal Articles

RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus

Phillip M. Garfin, MD, PhD, Patrick Viatour, PharmD, PhD, Dullei Min, PhD, Jerrod Bryson, PhD, Kenneth I. Weinberg, MD, Nancy R. Manley, PhD, Julien Sage, PhD

Blood (2012) 120 (21): 835.

https://doi.org/10.1182/blood.V120.21.835.835

Published: 2012

Journal Articles

The Dual Bromodomain Protein Brd2 Controls Primary B Cell Mitogenesis and Cell Cycle in Mice Reconstituted with Lentivirus-Transduced HSCs

Wanda P. Blanton, MD, Fangnian Wang, MD, PhD, Hongsheng Liu, DMD, Paul Romesser, Douglas Faller, Gerald Denis, MSc, PhD

Blood (2008) 112 (11): 2465.

https://doi.org/10.1182/blood.V112.11.2465.2465

Published: 2008

Journal Articles

Roscovitine Prevents Alloreactive T Cell Expansion and TNF-a-Mediated Proinflammatory Gene Expression and Protects against GvHD.

Lequn Li, MD, PhD, Hui Wang, MD, PhD, Roderick Bronson, MD, Vassiliki Boussiotis, MD, PhD

Blood (2008) 112 (11): 2341.

https://doi.org/10.1182/blood.V112.11.2341.2341

Published: 2008

Journal Articles

Codanin-1, the Protein Encoded by the Gene Mutated in Congenital Dyserythropoietic Anemia Type I ( CDAN1 ), Is Cell Cycle Regulated

Sharon Noy-Lotan, MSc, Orly Dgany, PhD, Roxane Lahmi, MSc, Nathaly Marcoux, PhD, Tanya Krasnov, MSc, Nissan Yissachar, MSc, Doron Ginsberg, PhD, Benny Motro, PhD, Peretz Resnitzky, MD, Isaac Yaniv, MD, Gary Kupfer, MD, Hannah Tamary, MD

Blood (2008) 112 (11): 483.

https://doi.org/10.1182/blood.V112.11.483.483

Published: 2008

Journal Articles

Coordinate Interstitial Deletion of Retinoblastoma ( RB1 ) and Neurobeachin ( NBEA ) Is a Recurring Event in Multiple Myeloma.

Julie O’Neal, AnnaLynn Molitoris, Feng Gao, Anjum Hassan, Ryan Monahan, Samantha Barrios, Kathy Weilbaecher, Ravi Vij, Michael H. Tomasson

Blood (2007) 110 (11): 2480.

https://doi.org/10.1182/blood.V110.11.2480.2480

Published: 2007

Journal Articles

Roscovitine Prevents TCR-Mediated T Cell Clonal Expansion In-Vitro and Protects Against GvHD In-Vivo.

Lequn Li, MD, PhD, Hui Wang, MD, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2007) 110 (11): 318.

https://doi.org/10.1182/blood.V110.11.318.318

Published: 2007

Journal Articles

A Novel p27 kip1 -Smad3 Regulated Pathway Is Involved in Induction of T Cell Tolerance.

Lequn Li, MD, PhD, Yoshiko Iwamoto, Alla Berezovskaya, Vassiliki A. Boussiotis, MD, PhD

Blood (2006) 108 (11): 867.

https://doi.org/10.1182/blood.V108.11.867.867

Published: 2006

Journal Articles

CD28 Costimulation Induces Transcription of SKP2 and CKS1 , the Substrate Recognition Components of the Skp1-Cullin-F-box Ubiquitin Ligase, SCF Skp2 .

Leonard J. Appleman, MD, PhD, Irene Chernova, Lequn Li, MD, PhD, Vassiliki Boussiotis, MD, PhD

Blood (2006) 108 (11): 869.

https://doi.org/10.1182/blood.V108.11.869.869

Published: 2006

Journal Articles

Defects in E2F1/2 Expression Are Associated with Abnormalities in Cell Cycle and Differentiation in EKLF-Deficient Erythroid Cells.

Andre M. Pilon, Murat O. Arcasoy, MD, Serena E. Vayda, Holly K. Dressman, PhD, James J. Bieker, PhD, David M. Bodine, PhD, Patrick G. Gallagher, MD

Blood (2006) 108 (11): 84.

https://doi.org/10.1182/blood.V108.11.84.84

Published: 2006

NARROW

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

In Vivo Genome-Wide Crispr Library Screen in a Xenograft Mouse Model of Tumor Growth and Metastasis of Multiple Myeloma

EZH2 Enables the Proliferation of Germinal Center B Cells and DLBCL through a Rb-E2F1 Positive Feedback Loop Involving Repression of CDKN1A

Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo

Discovery and Characterization of Promoter and Super-Enhancer-Associated Dependencies through E2F and BET Bromodomains in Multiple Myeloma

Proliferation-Independent Functions of the E2F-2 Transcription Factor during Terminal Erythroid Maturation

Atypical E2F Dependent Dysregulation Of Cell Cycling By Microrna-142 Regulates T-Cell Responses and Experimental Graft-Versus-Host Disease

A new twist to the GATA switch

RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus

The Dual Bromodomain Protein Brd2 Controls Primary B Cell Mitogenesis and Cell Cycle in Mice Reconstituted with Lentivirus-Transduced HSCs

Roscovitine Prevents Alloreactive T Cell Expansion and TNF-a-Mediated Proinflammatory Gene Expression and Protects against GvHD.

Codanin-1, the Protein Encoded by the Gene Mutated in Congenital Dyserythropoietic Anemia Type I ( CDAN1 ), Is Cell Cycle Regulated

Coordinate Interstitial Deletion of Retinoblastoma ( RB1 ) and Neurobeachin ( NBEA ) Is a Recurring Event in Multiple Myeloma.

Roscovitine Prevents TCR-Mediated T Cell Clonal Expansion In-Vitro and Protects Against GvHD In-Vivo.

A Novel p27 kip1 -Smad3 Regulated Pathway Is Involved in Induction of T Cell Tolerance.

CD28 Costimulation Induces Transcription of SKP2 and CKS1 , the Substrate Recognition Components of the Skp1-Cullin-F-box Ubiquitin Ligase, SCF Skp2 .

Defects in E2F1/2 Expression Are Associated with Abnormalities in Cell Cycle and Differentiation in EKLF-Deficient Erythroid Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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