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Journal Articles

Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability

Rami Abu-Fanne, Victoria Stepanova, Rustem I. Litvinov, Suhair Abdeen, Khalil Bdeir, Mohamed Higazi, Emad Maraga, Chandrasekaran Nagaswami, Alexander R. Mukhitov, John W. Weisel, Douglas B. Cines, Abd Al-Roof Higazi

Blood (2019) 133 (5): 481–493.

https://doi.org/10.1182/blood-2018-07-861237

Published: 2019

Includes: Supplemental data

Journal Articles

Contact system sends defensins to the rescue

Laura D. Healy, Owen J. T. McCarty

Blood (2019) 133 (5): 385–386.

https://doi.org/10.1182/blood-2018-12-887547

Published: 2019

Journal Articles

Hierarchical Differences in Defensin Gene Expression in Plasmacytoid Dendritic Cells and Progenitor Cells from Five Different Hematopoietic Stem Cell Transplant Graft Types

Cynthia R. Giver, PhD, Ernestine Anna Mahar, B.S., Sakura Hosoba, MD, Jeanne Kowalski, PhD, Sandra Seby, MSc, Xinyan A. Zhang, PhD MPH, Steven M. Devine, MD, Edmund K. Waller, MD

Blood (2017) 130 (Supplement 1): 1924.

https://doi.org/10.1182/blood.V130.Suppl_1.1924.1924

Published: 2017

Journal Articles

Quantification of Erythroblast- and Myelocyte-Derived mRNAs in Plasma Exosomes As an Indicator of Bone Marrow Status in Patients with Various Types of Anemias and Myeloproliferative Disorders

Masato Mitsuhashi, MD PhD, Taku Murakami, PhD, Teodora Kuzmanovic, Cassandra M. Hirsch, BSc, Hideki Makishima, MD, PhD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 5070.

https://doi.org/10.1182/blood.V128.22.5070.5070

Published: 2016

Journal Articles

Human Neutrophil Peptides (HNPs) Enhance Thrombus Formation Under Flow By Inhibiting Proteolytic Activity of Plasma ADAMTS13 Metalloprotease

Vikram G. Pillai, PhD, Jialing Bao, PhD, Jenny McDaniel, MD, Catherine B. Zander1, PhD, Wenjing Cao, MD, PhD, Khalil Bdeir, PhD, Douglas B. Cines, MD, X. Long Zheng, MD PhD

Blood (2015) 126 (23): 105.

https://doi.org/10.1182/blood.V126.23.105.105

Published: 2015

Journal Articles

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

Yiming Huang, MD, Mary J Elliott, BS, Thomas O Miller, BS, Janina Ratajczak, MD PhD, Larry D Bozulic, PhD, Yujie Wen, MD PhD, Hong Xu, MD, Mariusz Z Ratajczak, MD PhD, Suzanne T. Ildstad, MD

Blood (2014) 124 (21): 1106.

https://doi.org/10.1182/blood.V124.21.1106.1106

Published: 2014

Journal Articles

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases in Vivo

Andreas Glenthoj, MDPhD, Katrin Nickles, DMD, Jack B Cowland, PhD, Niels Borregaard, MDPhD

Blood (2014) 124 (21): 1400.

https://doi.org/10.1182/blood.V124.21.1400.1400

Published: 2014

Journal Articles

Inhibition of ADAMTS13 Activity By Human Neutrophil Peptide 1 (HNP-1): Potential Link Between Inflammation, Onset of Thrombotic Thrombocytopenic Purpura, and Other Thrombosis

Jialing Bao, PhD, Khalil Bdeir, PhD, Don L. Siegel, MD, PhD, Douglas B. Cines, MD, X. Long Zheng, MD, PhD

Blood (2014) 124 (21): 599.

https://doi.org/10.1182/blood.V124.21.599.599

Published: 2014

Journal Articles

Eriguchi Y, Takashima S, Oka H, et al. Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins. Blood . 2012;120(1): 223-231 .

Blood (2014) 124 (7): 1201.

https://doi.org/10.1182/blood-2014-07-586628

Published: 2014

Journal Articles

Superoxide Dismutase 2 (Sod2) Expression Is Highly Decreased In Chronic Myeloid Leukemia (CML): Contribution To Genetic Instability In Bcr-Abl-Expressing Leukemic Cells

Sandrine Girerd, Lucie Tosca, PharmD, PhD, Olivier Herault, MD, PhD, Christine Vignon, PhD, Denis Biard, PhD, Fatima Dkhissi, PhD, Clémentine Bouneau, Djamel Aggoune, Angelina Bertrand, Marie Laure Bonnet, Nathalie Sorel, PhD, Gerard Tachdjian, MD, PhD, François Guilhot, MD, Joelle Guilhot, PhD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, MD, PhD

Blood (2013) 122 (21): 3980.

https://doi.org/10.1182/blood.V122.21.3980.3980

Published: 2013

Journal Articles

Human and Murine β-Defensin-Derived Peptides Induce Rapid Mobilization Of Murine Hematopoietic Stem and Progenitor Cells Via Activation Of CXCR4 Signaling and CXCL12 Release

Amir Schajnovitz, PhD, Alexander Kalinkovich, MD, PhD, Kfir Lapid, PhD, Alexander Berchanski, PhD, Tomer Itkin, PhD, Aya Ludin, DMD, PhD, Shiri Gur-Cohen, MSc, Karin Golan, MSc, Borja Saez, PhD, Orit Kollet, PhD, Kerstin Ahrens, PhD, Ehrahrdt Proksch, MD, PhD, Aviva Lapidot, PhD, Matityahu Fridkin, PhD, David T. Scadden, MD, Tsvee Lapidot, PhD

Blood (2013) 122 (21): 890.

https://doi.org/10.1182/blood.V122.21.890.890

Published: 2013

Journal Articles

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Migration and homing—evidence That Cationic Antimicrobial Peptides (C3a, LL-37, and β2-defensin) Prime (enhance) the Responsiveness of These Cells to a Low SDF-1 Gradient by Promoting Secretion of ATP, Indicating the Involvement of an Autocrine Purinergic Loop in Their Migration.

Gabriela Schneider, Ph.D., ChiHwa Kim, Ph.D., Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2012) 120 (21): 2989.

https://doi.org/10.1182/blood.V120.21.2989.2989

Published: 2012

Journal Articles

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Homing - an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1

Gabriela Schneider, Ph.D., Kim ChiHwa, PhD, Ahmed Abdel-Latif, MD, Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2012) 120 (21): 1247.

https://doi.org/10.1182/blood.V120.21.1247.1247

Published: 2012

Journal Articles

Intestinal Microbiota: From Inflammatory Bowel Disease to Bone Marrow Transplantation

Ernst Holler, PhD, Peter Oefner, Karin Landfried, MD, Josef Koestler, Elisabeth Huber, MD, Katrin Peter, Julia Ammer, MD, Gerhard Rogler, Marina Kreutz, Rainer Spang, Thomas Hehlgans, Matthias Edinger, Daniel Wolff, Andre Gessner, Reinhard Andreesen

Blood (2012) 120 (21): SCI-50.

https://doi.org/10.1182/blood.V120.21.SCI-50.SCI-50

Published: 2012

Journal Articles

Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins

Yoshihiro Eriguchi, Shuichiro Takashima, Hideyo Oka, Sonoko Shimoji, Kiminori Nakamura, Hidetaka Uryu, Shinji Shimoda, Hiromi Iwasaki, Nobuyuki Shimono, Tokiyoshi Ayabe, Koichi Akashi, Takanori Teshima

Blood (2012) 120 (1): 223–231.

https://doi.org/10.1182/blood-2011-12-401166

Published: 2012

Journal Articles

Processing of α-Defensin in Subcellular Fractionations of Promyelocytic Cell Line PLB-985

Andreas Glenthøj, Jack B Cowland, Niels Borregaard

Blood (2011) 118 (21): 2163.

https://doi.org/10.1182/blood.V118.21.2163.2163

Published: 2011

Journal Articles

-52G/A Gene Variant in the β-Defensin-1 ( DEBF1 ) Influences the Development of Severe Acute Graft Versus Host Disease (aGvHD) After Allogeneic Stem Cell Transplantation (Allo-SCT). Functional Association of This Variant with a Low Anti- Inflammatory Response

Beatriz Martin-Antonio, Damià Romero, David Gallardo, MD, PhD, Anna Bosch, Ildefonso Espigado, MD, PhD, Ismael Buno, Carolina Martinez-Laperche, Antonio Jimenez-Velasco, Rafael De La Camara, MD, Salut Brunet, Nieto B Jose, Jose Román, Maria Suarez-LLedo, Francesc Fernandez-Avilés, Carmen Martinez, Montserrat Rovira, Alvaro Urbano-Ispizua, MD

Blood (2011) 118 (21): 3052.

https://doi.org/10.1182/blood.V118.21.3052.3052

Published: 2011

Journal Articles

Serglycin participates in retention of α-defensin in granules during myelopoiesis

Andreas Glenthøj, Jack B. Cowland, Niels H. Heegaard, Maria T. Larsen, Niels Borregaard

Blood (2011) 118 (16): 4440–4448.

https://doi.org/10.1182/blood-2011-06-362947

Published: 2011

Includes: Supplemental data

Journal Articles

Graft-Versus-Host Disease Alters Intestinal Microbial Ecology by Inhibiting Production of Enteric Defensins

Yoshihiro Eriguchi, Shuichiro Takashima, Noriko Miyake, Yoji Nagasaki, Nobuyuki Shimono, Koichi Akashi, Takanori Teshima

Blood (2010) 116 (21): 244.

https://doi.org/10.1182/blood.V116.21.244.244

Published: 2010

Journal Articles

In Vitro Generation of NK22 Cells From Hematopoietic Stem Cells

Qin Tang, MS, Ahn Yong-Oon, Ph.D., Peter Southern, Ph.D., Bruce R. Blazar, MD, Jeffrey S Milller, MD, Michael Verneris, MD

Blood (2010) 116 (21): 108.

https://doi.org/10.1182/blood.V116.21.108.108

Published: 2010

NARROW

Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability

Contact system sends defensins to the rescue

Hierarchical Differences in Defensin Gene Expression in Plasmacytoid Dendritic Cells and Progenitor Cells from Five Different Hematopoietic Stem Cell Transplant Graft Types

Quantification of Erythroblast- and Myelocyte-Derived mRNAs in Plasma Exosomes As an Indicator of Bone Marrow Status in Patients with Various Types of Anemias and Myeloproliferative Disorders

Human Neutrophil Peptides (HNPs) Enhance Thrombus Formation Under Flow By Inhibiting Proteolytic Activity of Plasma ADAMTS13 Metalloprotease

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases in Vivo

Inhibition of ADAMTS13 Activity By Human Neutrophil Peptide 1 (HNP-1): Potential Link Between Inflammation, Onset of Thrombotic Thrombocytopenic Purpura, and Other Thrombosis

Eriguchi Y, Takashima S, Oka H, et al. Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins. Blood . 2012;120(1): 223-231 .

Superoxide Dismutase 2 (Sod2) Expression Is Highly Decreased In Chronic Myeloid Leukemia (CML): Contribution To Genetic Instability In Bcr-Abl-Expressing Leukemic Cells

Human and Murine β-Defensin-Derived Peptides Induce Rapid Mobilization Of Murine Hematopoietic Stem and Progenitor Cells Via Activation Of CXCR4 Signaling and CXCL12 Release

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Homing - an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1

Intestinal Microbiota: From Inflammatory Bowel Disease to Bone Marrow Transplantation

Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins

Processing of α-Defensin in Subcellular Fractionations of Promyelocytic Cell Line PLB-985

-52G/A Gene Variant in the β-Defensin-1 ( DEBF1 ) Influences the Development of Severe Acute Graft Versus Host Disease (aGvHD) After Allogeneic Stem Cell Transplantation (Allo-SCT). Functional Association of This Variant with a Low Anti- Inflammatory Response

Serglycin participates in retention of α-defensin in granules during myelopoiesis

Graft-Versus-Host Disease Alters Intestinal Microbial Ecology by Inhibiting Production of Enteric Defensins

In Vitro Generation of NK22 Cells From Hematopoietic Stem Cells

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American Society of Hematology

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