Page 1 | Search Results | Blood | American Society of Hematology

1-17 of 17

Sort by

Sort Order Select

Journal Articles

Bone Marrow Stroma Protects FLT3 Acute Myeloid Leukemia (AML) through CYP3A4-Mediated Drug Metabolization of FLT3 Tyrosine Kinase Inhibitors (TKIs)

Yu-Ting Chang, MS, Daniela Hernandez, MD, Gabriel Ghiaur, MD PhD, Mark J. Levis, MD, Richard J. Jones, MD

Blood (2017) 130 (Supplement 1): 2519.

https://doi.org/10.1182/blood.V130.Suppl_1.2519.2519

Published: 2017

Journal Articles

Concomitant Use of Midostaurin with Strong CYP3A4 Inhibitors: An Analysis from the Ratify Trial

Taoufik Ouatas, PhD, Vincent Duval, PharmD, Karen Sinclair, PhD, Noah Berkowitz, MD PhD

Blood (2017) 130 (Supplement 1): 3814.

https://doi.org/10.1182/blood.V130.Suppl_1.3814.3814

Published: 2017

Journal Articles

Comorbidity Burden and Use of Concomitant Medications at CML Diagnosis: A Retrospective Analysis of 470 Patients from the Polish Adult Leukemia Group (PALG) Registry

Joanna Gora-Tybor, Tomasz Sacha, Joanna Waclaw, Joanna Niesiobedzka, Olga Grzybowska-Izydorczyk, Ewa Medras, Izabela Deren-Wagemann, Elzbieta Patkowska, Ilona Seferynska, Krzysztof Lewandowski, Anna Wache, Beata Blajer-Olszewska, Marzena Watek, Krzysztof Warzocha, Krzysztof Jamroziak

Blood (2016) 128 (22): 1909.

https://doi.org/10.1182/blood.V128.22.1909.1909

Published: 2016

Journal Articles

First-in-Human Phase 1a Study of the Safety, Pharmacokinetics, and Pharmacodynamics of the Noncovalent Bruton Tyrosine Kinase (BTK) Inhibitor SNS-062 in Healthy Subjects

Linda L. Neuman, MD MBA, Renee Ward, MD PhD, David Arnold, Daniel L. Combs, BS, Deena Gruver, MS, Wendy Hill, MBA, Josué Mfopou Kunjom, MD PhD, Langdon L. Miller, MD, Judith A. Fox, PhD

Blood (2016) 128 (22): 2032.

https://doi.org/10.1182/blood.V128.22.2032.2032

Published: 2016

Journal Articles

The constitutive androstane receptor is a novel therapeutic target facilitating cyclophosphamide-based treatment of hematopoietic malignancies

Duan Wang, Linhao Li, Hui Yang, Stephen S. Ferguson, Maria R. Baer, Ronald B. Gartenhaus, Hongbing Wang

Blood (2013) 121 (2): 329–338.

https://doi.org/10.1182/blood-2012-06-436691

Published: 2013

Includes: Supplemental data

Journal Articles

Association Between CYP3A4 Polymorphisms, Trough Imatinib Plasma Concentration and Cytogenetic Response in Chronic Phase Chronic Myeloid Leukemia (CML-CP)

Vikram Gota, MD, PGDCT, Anupam Sharma, MSc, Amey Paradkar, Anand Patil, M.Pharm, Navin Khattry, MD, DM, Hari Menon, MD, DM, Anuradha Choughule, PhD, Pratibha Amare, PhD, Shripad Banavali, Brijesh Arora, MD, DM

Blood (2012) 120 (21): 3788.

https://doi.org/10.1182/blood.V120.21.3788.3788

Published: 2012

Journal Articles

Influence of Genetic Polymorphisms in CYP1A2 , CYP2C19, CYP3A4 , GSTP1 , MDR1 and PSMB5 Genes in Toxicity and Response to Induction Therapy in Multiple Myeloma Patients Included in the Trial of the Spanish PETHEMA/GEM 05 for Newly Diagnosed MM Elderly Patients (Age 65 or More)

Blood (2011) 118 (21): 1412.

https://doi.org/10.1182/blood.V118.21.1412.1412

Published: 2011

Journal Articles

Population Pharmacokinetics of Busulfan in Patients with Beta Thalassaemia Major Undergoing HSCT Reveals Body Weight, GSTA1 and CYP3A4 Promoter Polymorphisms as Main Covariates Explaining the Inter-Individual Variation.

Poonkuzhali Balasubramanian, Ph.D, John Carl Panetta, Ph.D, Salamun Desire, M.Sc, Shaji R Velayudhan, Ph.D, Vikram Mathews, MD, Biju George, MD, Auro Viswabandya, MD, Mammen Chandy, MD, Alok Srivastava, MD

Blood (2009) 114 (22): 3349.

https://doi.org/10.1182/blood.V114.22.3349.3349

Published: 2009

Journal Articles

Pharmacogenetic study in Hodgkin lymphomas reveals the impact of UGT1A1 polymorphisms on patient prognosis

Vincent Ribrag, Serge Koscielny, Olivier Casasnovas, Cecile Cazeneuve, Pauline Brice, Franck Morschhauser, Jean Gabarre, Aspasia Stamatoullas, Gilbert Lenoir, Gilles Salles

Blood (2009) 113 (14): 3307–3313.

https://doi.org/10.1182/blood-2008-03-148874

Published: 2009

Journal Articles

Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas

Cristina Rodríguez-Antona, Susanna Leskelä, Magdalena Zajac, Marta Cuadros, Javier Alvés, Maria Victoria Moneo, Carmen Martín, Juan Cruz Cigudosa, Amancio Carnero, Mercedes Robledo, Javier Benitez, Beatriz Martínez-Delgado

Blood (2007) 110 (9): 3345–3351.

https://doi.org/10.1182/blood-2007-02-075036

Published: 2007

Includes: Supplemental data

Journal Articles

Influence of Genetic Single Nucleotide Polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 Genes on Survival and Treatment Related Toxicity in Patients with Multiple Myeloma Treated in the HOVON 24 Trial.

Pieter Sonneveld, MD, Celine Schilthuizen, Henk Lokhorst, MD, Edo Vellenga, MD, Reinier Raymakers, MD, Yvonne de Knegt, Eric Kamst, MSc, Bronno van der Holt, MSc

Blood (2005) 106 (11): 505.

https://doi.org/10.1182/blood.V106.11.505.505

Published: 2005

Journal Articles

Drug Metabolism and Disposition Genes in Israeli HIV Patients: MDR1 and CYP3A4 Polymorphisms May Affect Susceptibility to HIV but Not the Course of the Disease.

Meirav Kedmi, MD, Sara Bar Cohen, PhD, Michelle Hauzi, RN, Shlomo Maayan, MD, Deborah Rund, MD

Blood (2005) 106 (11): 1434.

https://doi.org/10.1182/blood.V106.11.1434.1434

Published: 2005

Journal Articles

Regulatory Proteins Bind at the Polymorphic NFSE Element of CYP3A4.

Tal David-Kalish, BA, RN, Deborah Rund, MD, Elad Malik, MD, Sara Bar Cohen, PhD

Blood (2005) 106 (11): 4453.

https://doi.org/10.1182/blood.V106.11.4453.4453

Published: 2005

Journal Articles

The Correlation between CYP3A4 Genetic Polymorphism and Children with Acute Leukemia.

Xiao-jun Yuan, MD, PhD, Long-jun Gu, MD, Hui-jun Zhao, MD, Jing-yan Tang, MD, PhD

Blood (2005) 106 (11): 4508.

https://doi.org/10.1182/blood.V106.11.4508.4508

Published: 2005

Journal Articles

Polymorphisms in Drug Metabolism/Disposition Genes and Increased Susceptibility to Adult De Novo AML: MDR1 and CYP3A4.

Meirav Kedmi, MD, Sara B. Cohen, PhD, Deborah Rund, MD

Blood (2004) 104 (11): 2078.

https://doi.org/10.1182/blood.V104.11.2078.2078

Published: 2004

Journal Articles

Study on the Phenotype Polymorphism of CYP3A4 Gene in Chinese Children with Acute Leukemia.

Xiao-jun Yuan, Ph.D, Long-Jun Gu, M.D, Hui-jun Zhao, M.D, Jin-cai Zhao, Jing-Yan Tang, M.D, Hui-liang Xue, M.D.

Blood (2004) 104 (11): 4376.

https://doi.org/10.1182/blood.V104.11.4376.4376

Published: 2004

Journal Articles

Pluripotent Unrestricted Somatic Stem Cells (USSC) from Cord Blood Generate Hepatocytes in Vivo, but In Vitro Convert into Immature Endodermal Precursors: The Critical Role of the Biological Niche.

Sandra Sensken, Juergen Enczmann, Ph.D., Thorsten Trapp, Ph.D., Esmail Zanjani, Ph.D., Peter Wernet, MD, Gesine Koegler, Ph.D.

Blood (2004) 104 (11): 3596.

https://doi.org/10.1182/blood.V104.11.3596.3596

Published: 2004

NARROW

Bone Marrow Stroma Protects FLT3 Acute Myeloid Leukemia (AML) through CYP3A4-Mediated Drug Metabolization of FLT3 Tyrosine Kinase Inhibitors (TKIs)

Concomitant Use of Midostaurin with Strong CYP3A4 Inhibitors: An Analysis from the Ratify Trial

Comorbidity Burden and Use of Concomitant Medications at CML Diagnosis: A Retrospective Analysis of 470 Patients from the Polish Adult Leukemia Group (PALG) Registry

First-in-Human Phase 1a Study of the Safety, Pharmacokinetics, and Pharmacodynamics of the Noncovalent Bruton Tyrosine Kinase (BTK) Inhibitor SNS-062 in Healthy Subjects

The constitutive androstane receptor is a novel therapeutic target facilitating cyclophosphamide-based treatment of hematopoietic malignancies

Association Between CYP3A4 Polymorphisms, Trough Imatinib Plasma Concentration and Cytogenetic Response in Chronic Phase Chronic Myeloid Leukemia (CML-CP)

Influence of Genetic Polymorphisms in CYP1A2 , CYP2C19, CYP3A4 , GSTP1 , MDR1 and PSMB5 Genes in Toxicity and Response to Induction Therapy in Multiple Myeloma Patients Included in the Trial of the Spanish PETHEMA/GEM 05 for Newly Diagnosed MM Elderly Patients (Age 65 or More)

Population Pharmacokinetics of Busulfan in Patients with Beta Thalassaemia Major Undergoing HSCT Reveals Body Weight, GSTA1 and CYP3A4 Promoter Polymorphisms as Main Covariates Explaining the Inter-Individual Variation.

Pharmacogenetic study in Hodgkin lymphomas reveals the impact of UGT1A1 polymorphisms on patient prognosis

Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas

Influence of Genetic Single Nucleotide Polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 Genes on Survival and Treatment Related Toxicity in Patients with Multiple Myeloma Treated in the HOVON 24 Trial.

Drug Metabolism and Disposition Genes in Israeli HIV Patients: MDR1 and CYP3A4 Polymorphisms May Affect Susceptibility to HIV but Not the Course of the Disease.

Regulatory Proteins Bind at the Polymorphic NFSE Element of CYP3A4.

The Correlation between CYP3A4 Genetic Polymorphism and Children with Acute Leukemia.

Polymorphisms in Drug Metabolism/Disposition Genes and Increased Susceptibility to Adult De Novo AML: MDR1 and CYP3A4.

Study on the Phenotype Polymorphism of CYP3A4 Gene in Chinese Children with Acute Leukemia.

Pluripotent Unrestricted Somatic Stem Cells (USSC) from Cord Blood Generate Hepatocytes in Vivo, but In Vitro Convert into Immature Endodermal Precursors: The Critical Role of the Biological Niche.

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only