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Journal Articles

HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation

Dijiong Wu, MD, Man Li, PhD, Lianjun Zhang, PhD, Jing Qi, PhD, Chun-Wei David Chen, PhD, Xin He, PhD, Yinghui Zhu, PhD, Haojie Dong, PhD, Jie Sun, PhD, Ling Li, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD

Blood (2019) 134 (Supplement_1): 642.

https://doi.org/10.1182/blood-2019-124134

Published: 2019

Journal Articles

The Translational Switch of MYC Protein Aliases in Myeloma Tumor Cells

Erming Tian, PhD MBA, Jeffery R. Sawyer, Ricky D. Edmondson, Maurizio Zangari, MD, Christopher P. Wardell, PhD MSc, BSc, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Frits van Rhee, MD PhD

Blood (2019) 134 (Supplement_1): 4390.

https://doi.org/10.1182/blood-2019-131850

Published: 2019

Journal Articles

Biology of t(6;11) Fusion Proteins and Their Role in MLL -Rearranged Acute Leukemia Lineage Determination

Arpita Kundu, PhD, Eric Kowarz, PhD, Jennifer Reis, Rolf Marschalek, PhD

Blood (2019) 134 (Supplement_1): 5033.

https://doi.org/10.1182/blood-2019-123070

Published: 2019

Journal Articles

High-Resolution Next-Generation Whole Genome Optical Mapping As a Novel Molecular Diagnostic Tool for Comprehensive Assessment of Structural Chromosomal Variations in Myelodysplastic Syndromes

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban-Bravo, MD, Koji Sasaki, MD, Rajyalakshmi Luthra, PhD, Hui Yang, PhDMD, Gokce A. Toruner, MD PhD, Keyur P. Patel, MBBS, PhD, Saradhi Mallampati, DVM, PhD, Hagop M. Kantarjian, MD, Carlos E. Bueso-Ramos, MD PhD, L. Jeffrey Medeiros, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 5438.

https://doi.org/10.1182/blood-2019-131971

Published: 2019

Journal Articles

Novel KMT2A Partner Gene NUTM2A Revealed By Anchored Multiplex PCR in ALL

Svetlana Lebedeva, Elena Zerkalenkova, PhD, Olga Soldatkina, Michael Maschan, MD PhD, Alexey A. Maschan, MD, Galina Novichkova, MD PhD, Yulia Olshanskaya, MD PhD

Blood (2019) 134 (Supplement_1): 5203.

https://doi.org/10.1182/blood-2019-126602

Published: 2019

Journal Articles

Anti-MiR-126 Therapy for Inv(16) Acute Myeloid Leukemia

Lianjun Zhang, PhD, Le Xuan Truong Nguyen, PhD, Dijiong Wu, MD, Casey J Brewer, PhD, Xin He, PhD, Man Li, PhD, Dandan Zhao, MD, Guerry Jeanne Cook, PhD, Jing Qi, PhD, Herman Wu, BS, Bin Zhang, PhD, Ling Li, PhD, Marcin Kortylewski, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD

Blood (2019) 134 (Supplement_1): 3914.

https://doi.org/10.1182/blood-2019-123468

Published: 2019

Journal Articles

Dose-Adjusted EPOCH and Rituximab (DA-EPOCH-R) Treatment in Dual Expressor Diffuse Large B-Cell and Double/Triple Hit Lymphomas: TP53 Mutations Influence on Clinical Outcome

Anna Dodero, MD, Anna Guidetti, MD, Fabrizio Marino, MD, Cristiana Carniti, PhD, Stefania Banfi, Alessandra Tucci, MD, Monica Balzarotti, Antonello Domenico Cabras, MD, Valentina Monti, PhD, Liliana Franca Devizzi, MD, Lucia Farina, MD, Maria Chiara Di Chio, MD, Giuseppe Rossi, Carmelo Carlo-Stella, MD, Paolo Corradini

Blood (2019) 134 (Supplement_1): 4116.

https://doi.org/10.1182/blood-2019-124350

Published: 2019

Journal Articles

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Jonathan Miller, MD PhD, Ryan Hiltenbrand, MS, Tamara Lamprecht, BS, Aman Seth, MS, Sherif Abdelhamed, PhD, Ilaria Iacobucci, PhD, Charles G. Mullighan, MBBS, MD, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): 3775.

https://doi.org/10.1182/blood-2019-130768

Published: 2019

Journal Articles

Chromoplexy and Chromothripsis Are Important Prognostically in Myeloma and Deregulate Gene Function By a Range of Mechanisms

Cody Ashby, PhD, Eileen M Boyle, MD MSc, Brian A Walker, PhD, Michael A Bauer, PhD, Katie Rose Ryan, PhD, Judith Dent, Anjan Thakurta, Erin Flynt, Faith E. Davies, MD, Gareth Morgan, MD PhD

Blood (2019) 134 (Supplement_1): 3767.

https://doi.org/10.1182/blood-2019-130335

Published: 2019

Journal Articles

Impact and Outcomes of RAS gene Mutations in Core Binding Factor Acute Myeloid Leukemia

Hassan Awada, Ashwin Kishtagari, MBBS, Teodora Kuzmanovic, Jibran Durrani, Cassandra M Kerr, MS, Manja Meggendorfer, PhD, Anjali S. Advani, MD, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Torsten Haferlach, MD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 2720.

https://doi.org/10.1182/blood-2019-131301

Published: 2019

Journal Articles

A Phase Ib/II Study of the Histone Methyltransferase Inhibitor Pinometostat in Combination with Azacitidine in Patients with 11q23-Rearranged Acute Myeloid Leukemia

Kamal Menghrajani, MD, Sheng F Cai, MD PhD, Sean M. Devlin, PhD, Scott A. Armstrong, MD PhD, Richard Piekarz, MD PhD MS, BA, Michelle Rudek, PharmD, PhD, Martin S. Tallman, MD, Eytan M. Stein, MD

Blood (2019) 134 (Supplement_1): 2655.

https://doi.org/10.1182/blood-2019-121926

Published: 2019

Journal Articles

CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies

Blood (2019) 134 (Supplement_1): 2066.

https://doi.org/10.1182/blood-2019-131318

Published: 2019

Journal Articles

Svd-SRS: A Highly Specific Algorithm for Identifying Somatic Genomic Rearrangements in Haematological Malignancy

Lloyd Ian Bibby, MSc, BSc, Bernard Ramsahoye, MB, ChB, PhD FRCPath, MRCP

Blood (2019) 134 (Supplement_1): 2086.

https://doi.org/10.1182/blood-2019-124719

Published: 2019

Journal Articles

3D Telomeric Fingerprint of Advanced Cutaneous T-Cell Lymphoma

Marc Nicolas Bienz, MD MSc, Cheryl Taylor-Kashton, Naciba Benlimame, PhD, Tina Petrogiannis-Haliotis, MD PhD, Kevin Pehr, MD, Sabine Mai, PhD, Hans Knecht, MD

Blood (2019) 134 (Supplement_1): 1501.

https://doi.org/10.1182/blood-2019-124559

Published: 2019

Journal Articles

DNA Methylation-Based Classification Highlights the Role of the JAK-STAT Pathway in Acute Myeloid Leukemia

Brian Giacopelli, BS, Min Wang, Ada C Cleary, Yue-zhong Wu, MSc, Anna Reister Schultz, James S. Blachly, MD, Ann-Kathrin Eisfeld, MD, Kevin R Coombes, Clara D. Bloomfield, MD, Brian J. Druker, Jeffrey W. Tyner, John C. Byrd, MD, Christopher C. Oakes, PhD

Blood (2019) 134 (Supplement_1): 1413.

https://doi.org/10.1182/blood-2019-126212

Published: 2019

Journal Articles

CRISPR/Cas9 Generation of Npm1-Alk in Transplantable Murine Hematopoietic Stem Cells Accurately Models ALK-Positive Lymphoma in Recipients

Soumya Sundara Rajan, MSc, Lingxiao Li, PhD, Kranthi Kunkalla, Amit Dipak Amin, PhD, Nitin Agarwal, Francisco Vega, MD PhD, Jonathan H. Schatz, MD

Blood (2018) 132 (Supplement 1): 779.

https://doi.org/10.1182/blood-2018-99-114692

Published: 2018

Journal Articles

MLL-USP2 : An Underestimated New Entity of MLL -Rearranged Leukemia Identified By NGS Analysis

Claus Meyer, PhD, Bruno Lopes, PhD, Aurélie Caye-Eude, PharmD, Hélène Cavé, PharmD, PhD, Chloé Arfeuille, PhD, Rosemary Sutton, PhD, Nicola Venn, BSc, Patrizia Larghero, PhD, Seung Hwan Oh, MD, Grigory Tsaur, MD PhD, Marketa Zaliova, Jan Zuna, Vesa Juvonen, PhD, Renate Panzer-Grümayer, MD, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD, Mariana Emerenciano, PhD, Rolf Marschalek, PhD

Blood (2018) 132 (Supplement 1): 3920.

https://doi.org/10.1182/blood-2018-99-112594

Published: 2018

Journal Articles

Normal and Aberrant NKL-Code in B-Cell Development and Lymphoma

Stefan Nagel, PhD, MacLeod A.F. Roderick, PhD, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, MD PhD

Blood (2018) 132 (Supplement 1): 3901.

https://doi.org/10.1182/blood-2018-99-110286

Published: 2018

Journal Articles

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Bo-Rui Chen, PhD, Anagha Deshpande, PhD, Maria Kleppe, PhD, Narayana Yeddula, PhD, Sunnie Yoh, PhD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Sumit Chanda, PhD, Aniruddha J. Deshpande, PhD

Blood (2018) 132 (Supplement 1): 544.

https://doi.org/10.1182/blood-2018-99-119210

Published: 2018

Journal Articles

Genetic Heterogeneity and Evolution in Lymphoid Malignancies

Charles G. Mullighan, MBBS, MD

Blood (2018) 132 (Supplement 1): SCI-34.

https://doi.org/10.1182/blood-2018-99-109499

Published: 2018

NARROW

HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation

The Translational Switch of MYC Protein Aliases in Myeloma Tumor Cells

Biology of t(6;11) Fusion Proteins and Their Role in MLL -Rearranged Acute Leukemia Lineage Determination

High-Resolution Next-Generation Whole Genome Optical Mapping As a Novel Molecular Diagnostic Tool for Comprehensive Assessment of Structural Chromosomal Variations in Myelodysplastic Syndromes

Novel KMT2A Partner Gene NUTM2A Revealed By Anchored Multiplex PCR in ALL

Anti-MiR-126 Therapy for Inv(16) Acute Myeloid Leukemia

Dose-Adjusted EPOCH and Rituximab (DA-EPOCH-R) Treatment in Dual Expressor Diffuse Large B-Cell and Double/Triple Hit Lymphomas: TP53 Mutations Influence on Clinical Outcome

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Chromoplexy and Chromothripsis Are Important Prognostically in Myeloma and Deregulate Gene Function By a Range of Mechanisms

Impact and Outcomes of RAS gene Mutations in Core Binding Factor Acute Myeloid Leukemia

A Phase Ib/II Study of the Histone Methyltransferase Inhibitor Pinometostat in Combination with Azacitidine in Patients with 11q23-Rearranged Acute Myeloid Leukemia

CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies

Svd-SRS: A Highly Specific Algorithm for Identifying Somatic Genomic Rearrangements in Haematological Malignancy

3D Telomeric Fingerprint of Advanced Cutaneous T-Cell Lymphoma

DNA Methylation-Based Classification Highlights the Role of the JAK-STAT Pathway in Acute Myeloid Leukemia

CRISPR/Cas9 Generation of Npm1-Alk in Transplantable Murine Hematopoietic Stem Cells Accurately Models ALK-Positive Lymphoma in Recipients

MLL-USP2 : An Underestimated New Entity of MLL -Rearranged Leukemia Identified By NGS Analysis

Normal and Aberrant NKL-Code in B-Cell Development and Lymphoma

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Genetic Heterogeneity and Evolution in Lymphoid Malignancies

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American Society of Hematology

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American Society of Hematology

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