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Journal Articles

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Blood (2019) 134 (Supplement_1): 684.

https://doi.org/10.1182/blood-2019-127673

Published: 2019

Journal Articles

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Yuqi Zhu, Ye Yang, PhD, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2019) 134 (Supplement_1): 3102.

https://doi.org/10.1182/blood-2019-123815

Published: 2019

Journal Articles

Characterizing Dyskeratosis Congenita Caused By Parn Mutations in the Zebrafish

Anna Cordeiro, PhD, Adam P Deveau, MSc, Santhosh Dhanraj, PhD, Yigal Dror, MDFRCPC, Jason Berman, MD

Blood (2019) 134 (Supplement_1): 3744.

https://doi.org/10.1182/blood-2019-130147

Published: 2019

Journal Articles

RUNX1 Mutation Accompanied with Dysregulated Cellular Senescence in Lower-Risk Myelodysplastic Syndrome Patients Is Associated with Disease Progression

Monika Hruba, Jitka Vesela, Hana Votavova, PhD, Michaela Dostalova Merkerova, PhD MSc, David Kundrat, Katarina Szikszai, PhD, Marie Lauermanova, MD, Zuzana Zemanova, PhD, Anna Jonasova, MD PhD, Jaroslav Cermak, MD PhD, Monika Belickova, PhD

Blood (2019) 134 (Supplement_1): 4230.

https://doi.org/10.1182/blood-2019-131150

Published: 2019

Journal Articles

Bcor Mutations Cooperate with Tet2 Deficiency to Promote RAS Transformation of Mouse Hematopoietic Progenitors

Iman Fares, PhD, Rahul S. Vedula, MD, Shabbir M. Vahanvaty, Christopher S Waters, Marlise R. Luskin, MD, Priti Kumari, M.S., Marie McConkey, PhD, Anne Charles, BS, Kevin Copson, MA, Gregory A. Abel, MDMPH, Richard M. Stone, MD, Benjamin L. Ebert, MDPhD, R. Coleman Lindsley, MD PhD

Blood (2018) 132 (Supplement 1): 888.

https://doi.org/10.1182/blood-2018-99-120096

Published: 2018

Journal Articles

Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling

Lili Wang, MDPhD, Shanye Yin, PhD, Aina zurita Martinez, Fara Faye Regis, BS, Angela Brooks, PhD, Sarah E. M. Herman, PhD, Elisa Ten Hacken, PhD, Esther Obeng, MD PhD, Dean Campagna, BS, Mark D. Fleming, MD DPhil, Benjamin L. Ebert, MDPhD, Adrian Wiestner, MD, Ignaty Leshchiner, PhD, Gad Getz, PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2018) 132 (Supplement 1): 947.

https://doi.org/10.1182/blood-2018-99-117691

Published: 2018

Journal Articles

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Blood (2018) 132 (Supplement 1): 2748.

https://doi.org/10.1182/blood-2018-99-118183

Published: 2018

Journal Articles

Early HHV-6 Reactivation in CMV-Seronegative Cord Blood Transplant Recipients Is Associated with Inferior Relapse-Free and Overall Survival

Armin Rashidi, MD PhD, Maryam Ebadi, MD, Bassil Said, MD, Qing Cao, M.S., Jeffrey S. Miller, MD, Daniel J. Weisdorf, MD

Blood (2017) 130 (Supplement 1): 1935.

https://doi.org/10.1182/blood.V130.Suppl_1.1935.1935

Published: 2017

Journal Articles

Reduction of Dicer1 By Multiple Myeloma Cells in Mesenchymal Stem Cells Promotes Cellular Senescence and Tumor-Supporting Effect and Decreases the Differentiation

Juan Guo, Xiao Li, MD, Youshan Zhao, Chengming Fei, Chunkang Chang, PhD, Sida Zhao, Qingqing Zheng

Blood (2017) 130 (Supplement 1): 4399.

https://doi.org/10.1182/blood.V130.Suppl_1.4399.4399

Published: 2017

Journal Articles

Novel Role of CEBPÎ² As a Transcriptional Repressor of Transposable Elements

Devi Thiagarajan, Stephen Capone, BS, Anthony Colombo, Timothy Junius Triche, Jr., PhD, Giridharan Ramsingh, MD

Blood (2017) 130 (Supplement 1): 771.

https://doi.org/10.1182/blood.V130.Suppl_1.771.771

Published: 2017

Journal Articles

HUWE1 Inhibition As a Therapeutic Strategy to Target MYC in MM

Lisa J Crawford, BSc, PhD, Dharminder Chauhan, PhD, Alexandra E Irvine, PhD FRCPath

Blood (2017) 130 (Supplement 1): 3077.

https://doi.org/10.1182/blood.V130.Suppl_1.3077.3077

Published: 2017

Journal Articles

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Gang Xiao, PhD, Chao Hong, PhD, Huimin Geng, PhD, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 882.

https://doi.org/10.1182/blood.V130.Suppl_1.882.882

Published: 2017

Journal Articles

Feedback Regulation of STAT5 Is Critical to Balance MYC and BCL6-Dependent Transcriptional Programs That Regulate Cell Size and Glucose Metabolism

Zhengshan Chen, MD PhD, Huimin Geng, PhD, Lars Klemm, BSc, MSc, Lai N Chan, PhD, Brass Daniel, PhD, Warren S. Alexander, PhD, Cheryl L. Willman, MD, Markus Müschen, MD PhD

Blood (2016) 128 (22): 4069.

https://doi.org/10.1182/blood.V128.22.4069.4069

Published: 2016

Journal Articles

Endothelial JAK2 V617F Expression Drives Inflammation and Cellular Senescence; New Evidence for the Roles of Endothelial Cells in MPN-Related Clotting Abnormalities?

Megan E Cosgrove, PhD, Rakesh Suman, PhD, Helen J Harrison, RN, Gillian E Jackson, RN, Martin R Howard, MBChB, MD FRCP, FRCPath, Ian S Hitchcock, PhD

Blood (2016) 128 (22): 3134.

https://doi.org/10.1182/blood.V128.22.3134.3134

Published: 2016

Journal Articles

Inhibition of Both Activated p38 Mapkα and mTORC1 Potentiates the Effect of SR1 on Promoting Hematopoietic Reconstitution of E x V ivo Expanded Human Umbilical Cord Blood Hematopoietic Stem Cells

Xiao Ma, Xiaoyi Li, Danyue Peng, Huifang Wang, Lei Li, Hao Zhou, Daohong Zhou, Yi Luo, Lingbo Liu

Blood (2016) 128 (22): 2173.

https://doi.org/10.1182/blood.V128.22.2173.2173

Published: 2016

Journal Articles

DLX1 Affects Cell Cycle and Proliferation of Myeloid Leukemia Cells In Vitro and In Vivo

Katerina Rejlova, Miroslava Kardosova, Martina Slamova, Marketa Zaliova, Meritxell Alberich-Jorda, Jan Trka, MD PhD, Julia Starkova

Blood (2016) 128 (22): 1666.

https://doi.org/10.1182/blood.V128.22.1666.1666

Published: 2016

Journal Articles

Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function

Lili Wang, MD PhD, Rutendo Gambe, BS, Jean Fan, BS, Youzhong Wan, PhD, Angela N Brooks, PhD, Jing Sun, PhD, Esther A. Obeng, MD PhD, Donna S Neuberg, ScD, Matthew Meyerson, MD PhD, Mark D. Fleming, MD DPhil, Benjamin L. Ebert, MD, Ruben D. Carrasco, MD PhD, Catherine J Wu, MD

Blood (2015) 126 (23): 366.

https://doi.org/10.1182/blood.V126.23.366.366

Published: 2015

Journal Articles

Impaired Lysophosphatidic Acid Receptor 3 Signaling in Mesenchymal Stromal Cells Promotes Multiple Myeloma Progression through Cellular Senescence and Transdifferentiation into Tumor-Associated Fibroblasts

Masahiko Kanehira, DVM, PhD, Tohru Fujiwara, MD PhD, Shinji Nakajima, MD PhD, Yoko Okitsu, MD PhD, Yasushi Ohnishi, MD PhD, Noriko Fukuhara, MD PhD, Ryo Ichinohasama, MD PhD, Hideo Harigae, MD PhD

Blood (2015) 126 (23): 1764.

https://doi.org/10.1182/blood.V126.23.1764.1764

Published: 2015

Journal Articles

CLL Mesenchymal Stromal Cells Have Decreased Replicative Potential and Senescent Phenotype: Clinical and Biologic Implications

Wei Ding, MD PhD, Charla Secreto, Xiaosheng Wu, PhD, Esteban Braggio, PhD, Yuji Zhang, PhD, Stephanie A. Smoley, Tait D. Shanafelt, MD, Jaime Davila, PhD, Timothy G Call, MD, Daniel L. Van Dyke, PhD, Diane F. Jelinek, Neil E. Kay, MD

Blood (2014) 124 (21): 3282.

https://doi.org/10.1182/blood.V124.21.3282.3282

Published: 2014

Journal Articles

The Key Role of PML in IFN-α Induced Cellular Senescence of Human Mesenchymal Stromal Cells

Shan Fu, Jieping Wei, Binsheng Wang, He Huang, MDPhD

Blood (2014) 124 (21): 3611.

https://doi.org/10.1182/blood.V124.21.3611.3611

Published: 2014

NARROW

Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Characterizing Dyskeratosis Congenita Caused By Parn Mutations in the Zebrafish

RUNX1 Mutation Accompanied with Dysregulated Cellular Senescence in Lower-Risk Myelodysplastic Syndrome Patients Is Associated with Disease Progression

Bcor Mutations Cooperate with Tet2 Deficiency to Promote RAS Transformation of Mouse Hematopoietic Progenitors

Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Early HHV-6 Reactivation in CMV-Seronegative Cord Blood Transplant Recipients Is Associated with Inferior Relapse-Free and Overall Survival

Reduction of Dicer1 By Multiple Myeloma Cells in Mesenchymal Stem Cells Promotes Cellular Senescence and Tumor-Supporting Effect and Decreases the Differentiation

Novel Role of CEBPÎ² As a Transcriptional Repressor of Transposable Elements

HUWE1 Inhibition As a Therapeutic Strategy to Target MYC in MM

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Feedback Regulation of STAT5 Is Critical to Balance MYC and BCL6-Dependent Transcriptional Programs That Regulate Cell Size and Glucose Metabolism

Endothelial JAK2 V617F Expression Drives Inflammation and Cellular Senescence; New Evidence for the Roles of Endothelial Cells in MPN-Related Clotting Abnormalities?

Inhibition of Both Activated p38 Mapkα and mTORC1 Potentiates the Effect of SR1 on Promoting Hematopoietic Reconstitution of E x V ivo Expanded Human Umbilical Cord Blood Hematopoietic Stem Cells

DLX1 Affects Cell Cycle and Proliferation of Myeloid Leukemia Cells In Vitro and In Vivo

Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function

Impaired Lysophosphatidic Acid Receptor 3 Signaling in Mesenchymal Stromal Cells Promotes Multiple Myeloma Progression through Cellular Senescence and Transdifferentiation into Tumor-Associated Fibroblasts

CLL Mesenchymal Stromal Cells Have Decreased Replicative Potential and Senescent Phenotype: Clinical and Biologic Implications

The Key Role of PML in IFN-α Induced Cellular Senescence of Human Mesenchymal Stromal Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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