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Journal Articles

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Murakami Shohei, PhD, Masayuki Yamamoto, MD PhD, Hozumi Motohashi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2351.
https://doi.org/10.1182/blood.V126.23.2351.2351
Published: 2015
Journal Articles

Keap1-Nrf2 System: Potential Role in Prevention of Sickle Cell Disease Organs Damages and Inflammation

Nadine Keleku-Lukwete, MD, Mikiko Suzuki, PhD, Akihito Otsuki, DDS, Kouhei Tsuchida, Saori Katayama, MD, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, MDPhD, Osamu Tanabe, MDPhD, James Doug Engel, PhD, Masue Imaizumi, MDPhD, Masayuki Yamamoto, MD PhD
Journal: Blood
Blood (2015) 126 (23): 411.
https://doi.org/10.1182/blood.V126.23.411.411
Published: 2015
Journal Articles

The Triterpenoid 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid and Its Derivatives Inhibit Mitochondrial Lon Protease Activity: A Potential Novel Pathway for the Induction of Lymphoma Cell Death.

Steven H. Bernstein, MD, Bin Lin, PhD, Shannon Hilchey, PhD, N. Villaluna, L. Chen, K. Madura, Kim Morse, Hollie Metcalf, Michael Andreeff, MD, PhD, Paul S Brookes, PhD, Carolyn K Suzuki, PhD
Journal: Blood
Blood (2009) 114 (22): 414.
https://doi.org/10.1182/blood.V114.22.414.414
Published: 2009
Journal Articles

Preferential Inhibition of Malignant Cell Growth by CDDO in Waldenström Macroglobulinemia.

Sherine F. Elsawa, PhD, Anne J. Novak, Ph.D., Marina Konopleva, M.D., Ph.D., Michael Andreeff, M.D., Ph.D., Thomas E. Witzig, M.D., Stephen M. Ansell, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2528.
https://doi.org/10.1182/blood.V108.11.2528.2528
Published: 2006
Journal Articles

Triterpenoids Display Single Agent Activity in a Mouse Model of CLL/SBL.

Christina L. Kress, BS, Marina Konopleva, Ph.D., Maryla Krajewska, M.D., Vanesa Martinez-Garcia, B.S., Sophie Lefebvre, Ph.D., Marc L. Hyer, Ph.D., Teresa McQueen, B.S., Michael Andreeff, Ph.D., John C. Reed, MD,Ph.D, Juan Zapata, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2530.
https://doi.org/10.1182/blood.V108.11.2530.2530
Published: 2006
Journal Articles

The Triterpenoids 2-cyano-3,12-dioxooleana-1,9-dien-28-oic Acid (CDDO) and Their Imidazole (CDDO-Im) and Dinitrile Derivatives (DI-CDDO) Elicit Apoptosis through a Novel Mitochondrial Pathway.

Paul Brookes, PhD, Andrew Tompkins, Kimberly Morse, Shannon Hilchey, PhD, Suhail Salim, Denise Ray, PhD, Richard Phipps, PhD, Steven H. Bernstein, MD
Journal: Blood
Blood (2005) 106 (11): 2426.
https://doi.org/10.1182/blood.V106.11.2426.2426
Published: 2005
Journal Articles

CDDO and CDDO-Im Reduce Tumor Burden in a Transgenic Mouse Model of CLL.

Juan M. Zapata, Ph.D., Christina L. Kress, BS, Marina Konopleva, Ph.D., Maryla Krajewska, M.D., Ph.D., Mark Hyer, Ph.D., Teresa McQueen, BS, Michael Andreeff, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3477.
https://doi.org/10.1182/blood.V104.11.3477.3477
Published: 2004
Journal Articles

Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells

Irene M. Pedersen, Juan M. Zapata, Temesgen Samuel, Fiona L. Scott, Guy S. Salvesen, Tadashi Honda, Gordon W. Gribble, Nanjoo Suh, Michael B. Sporn, Thomas J. Kipps, John C. Reed
Journal: Blood
Blood (2004) 104 (4): 932.
https://doi.org/10.1182/blood-2003-11-3774
Published: 2004
Journal Articles

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti–multiple myeloma (MM) activity and overcome bortezomib resistance

Dharminder Chauhan, Guilan Li, Klaus Podar, Teru Hideshima, Reshma Shringarpure, Laurence Catley, Constantine Mitsiades, Nikhil Munshi, Yu Tzu Tai, Nanjoo Suh, Gordon W. Gribble, Tadashi Honda, Robert Schlossman, Paul Richardson, Michael B. Sporn, Kenneth C. Anderson
Journal: Blood
Blood (2004) 103 (8): 3158–3166.
https://doi.org/10.1182/blood-2003-08-2873
Published: 2004