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Journal Articles

MYC Oncogene Abrogates Natural Killer (NK) Cell-Mediated Immune Surveillance of B- and T- Lymphoid Malignancies By Suppressing STAT1/2-Type I IFN Signaling

Srividya Swaminathan, PhD, Line Dam Heftdal, MD, Daniel Liefwalker, PhD, Renumathy Dhanasekaran, MD, Anja Deutzmann, PhD, Crista Horton, BS, Adriane Mosley, BS, Mariola Liebersbach, BS, Andrew Gentles, PhD, Holden T. Maecker, PhD, Dean Felsher, MD PhD

Blood (2019) 134 (Supplement_1): 730.

https://doi.org/10.1182/blood-2019-122607

Published: 2019

Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Veronika Bachanova, MD PhD, David H. McKenna, MD, Xianghua Luo, PhD, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD MS, Erica D. Warlick, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Guy Brachya, PhD, Tony Peled, MSc, Jeffrey S. Miller, MD

Blood (2019) 134 (Supplement_1): 777.

https://doi.org/10.1182/blood-2019-130476

Published: 2019

Journal Articles

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Blood (2019) 134 (Supplement_1): 473.

https://doi.org/10.1182/blood-2019-127122

Published: 2019

Journal Articles

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

Karin Gustafsson, PhD, Nikolas Barkas, PhD, Ninib Baryawno, PhD, Elizabeth W Scadden, Nicolas Severe, PhD, Joel A Spencer, PhD, Hayalneh Gessessew, Kameron Kooshesh, Jimin Guo, PhD, Charles Lin, PhD, Peter Kharchenko, PhD, David T. Scadden, MD

Blood (2019) 134 (Supplement_1): 586.

https://doi.org/10.1182/blood-2019-126708

Published: 2019

Journal Articles

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Athanasios Papadas, MD, Evan Flietner, BS, Zachary Morrow, BS, Joshua Wiesner, Alexander Cicala, Adam Pagenkopf, BS, Chelsea L. Hope, PhD, Adhithi Rajagopalan, BS, Zhi Wen, PhD, Philip Emmerich, Dustin Deming, Shigeki Miyamoto, PhD, Peiman Hematti, MD, Natalie Scott Callander, MD, Alexander Rakhmilevich, Mario Otto, MD PhD, Christian M. Capitini, MD, Jing Zhang, PhD, Fotis Asimakopoulos, PhDMBBChir,

Blood (2019) 134 (Supplement_1): 1210.

https://doi.org/10.1182/blood-2019-131582

Published: 2019

Journal Articles

Enhancing Anti-Tumor Immunity and Responses to Immune Checkpoint Blockade By Suppressing Interleukin-10 in Chronic Lymphocytic Leukemia

Jacqueline R. Rivas, PhDBS, Sara S. Alhakeem, PhD, Joseph M. Eckenrode, PhD, Yinan Zhang, PhD, James P. Collard, BS, Gerhard C. Hildebrandt, MD, Roger A. Fleischman, MD PhD, Li Chen, PhD, Jon S. Thorson, PhD, Markos Leggas, PhD, Subbarao Bondada, PhD

Blood (2019) 134 (Supplement_1): 5486.

https://doi.org/10.1182/blood-2019-127178

Published: 2019

Journal Articles

Eomes and IL-10 Regulate Anti-Tumor Activity of T Cells in Chronic Lymphocytic Leukemia

Laura Llaó Cid, M.Sc, Philipp M Rößner, MD, Ekaterina Lupar, PhD, Bola S Hanna, PhD, Jérôme Paggetti, PhD, Etienne Moussay, PhD, Dolors Colomer, PhD, Sascha Dietrich, MD, Stephan Stilgenbauer, MD, Ana Izcue, PhD, Martina Seiffert, PhD

Blood (2019) 134 (Supplement_1): 4288.

https://doi.org/10.1182/blood-2019-128465

Published: 2019

Journal Articles

Telomere Shortening By Terc Knockout in the Eµ-TCL1 Transgenic Murine Model of CLL: Characterization of Disease Development and Survival

Billy Michael Chelliah Jebaraj, PhD, Annika Scheffold, PhD, André Lechel, Sarah-Fee Katz, PhD, Eugen Tausch, Johannes Bloehdorn, MD, Daniela Steinbrecher, PhD, Vanni Torresi, Christof Schneider, MD, Hartmut Döhner, MD, Daniel Mertens, PhD, Lenhard Rudolph, Stephan Stilgenbauer

Blood (2019) 134 (Supplement_1): 1732.

https://doi.org/10.1182/blood-2019-126878

Published: 2019

Journal Articles

Response to Bcma CAR-T Cells Correlates with Pretreatment Target Antigen Density and Is Improved By Small Molecule Inhibition of Gamma Secretase

Damian J. Green, MD, Margot Pont, PhD, Andrew J. Cowan, MD, Gabriel O Cole, Blythe Duke Sather, PhD, Anne M Nagengast, RN, Xaoling Song, Sushma Thomas, Brent L Wood, MD PhD, Michelle L Blake, PhD, Melissa G Works, PhD, Ted A Gooley, PhD, David G. Maloney, MD PhD, Stanley R. Riddell, MD

Blood (2019) 134 (Supplement_1): 1856.

https://doi.org/10.1182/blood-2019-129582

Published: 2019

Journal Articles

Development of an Allogeneic Anti-Bcma T Cell Therapy Utilizing a Novel Dimeric Antigen Receptor (DAR) Structure

Bei Bei Ding, PhD, John Dixon Gray, PhD, Nan Zhang, Yanliang Zhang, PhD, Xia Cao, MSc, Irina Krapf, MSc, Qingdong Mark Deng, Angel Wei, MD, Jerome B. Zeldis, MD PhD, Robert D. Knight, MD, Gunnar F. Kaufmann, PhD, Henry Ji, PhD, Wenzhong Guo, PhD

Blood (2019) 134 (Supplement_1): 1942.

https://doi.org/10.1182/blood-2019-131892

Published: 2019

Journal Articles

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Sara Piccinelli, Antonella Mancusi, PhD, Eni Hoxha, Loredana Ruggeri, MD, Franca Falzetti, MD, Alessandra Carotti, MD, Adelmo Terenzi, MD, Samanta Bonato, MD, Matteo Paradiso, MD, Tiziana Zei, Roberta Iacucci Ostini, Barbara Bigerna, Brunangelo Falini, MD PhD, Mauro Di Ianni, MD PhD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD

Blood (2019) 134 (Supplement_1): 1917.

https://doi.org/10.1182/blood-2019-125715

Published: 2019

Journal Articles

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies- Two-Year Follow-up of Multicenter Study in Singapore

Li Mei Poon, MBBS, MRCP, FRCPath, Yeh Ching Linn, MBBS, MRCP, Poh Lin Tan, Ziyi LIM, Balamurugan Vellayappan, Rajat Bhattacharyya, Ah Moy Tan, MD, Lip Kun Tan, MBBS, FRCP, FRCPath, Teck Guan Soh, Colin Phipps Diong, Wing H. Leung, MD PhD, Liang Piu Koh, MBBS, MRCP

Blood (2019) 134 (Supplement_1): 2039.

https://doi.org/10.1182/blood-2019-128014

Published: 2019

Journal Articles

Cytokine-Induced Memory-like (ML) NK Cells Persist for > 2 Months Following Adoptive Transfer into Leukemia Patients with a MHC-Compatible Hematopoietic Cell Transplant (HCT)

Jennifer A Foltz, PhD, Melissa M Berrien-Elliott, PhD, Carly Neal, B.S., Mark Foster, Ethan McClain, Tim Schappe, BS, Sweta Desai, Michelle Becker-Hapak, BS, Amanda F Cashen, MD, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 1954.

https://doi.org/10.1182/blood-2019-126004

Published: 2019

Journal Articles

Treatment with Acalibrutinib, Ibrutinib and CD19 CAR T Cells Restore the Number of Granulocytic Myeloid Derived Supressor Cells in CLL-Bearing Mice

Arantxa Romero-Toledo, MSc, Robin Sanderson, MRCP,FRCPath, John G. Gribben, MD DSc

Blood (2019) 134 (Supplement_1): 3032.

https://doi.org/10.1182/blood-2019-126697

Published: 2019

Journal Articles

In Vitro and in Vivo Activity of Melflufen in Amyloidosis

Ken Flanagan, PhD, Muntasir M Majumder, MSc, BPharm, Romika Kumari, PhD, Juho Miettinen, PhD, Ana Slipicevic, PhD, Sarah A. Holstein, MD PhD, Michelle L. Varney, MS, Minna Suvela, MSC, Fredrik Lehmann, PhD, Nina N. Nupponen, PhD, Caroline A Heckman, PhD

Blood (2019) 134 (Supplement_1): 3100.

https://doi.org/10.1182/blood-2019-125952

Published: 2019

Journal Articles

Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation

Jeffrey J. Bednarski, MD PhD, Clare Zimmerman, MD, Amanda F Cashen, MD, Sweta Desai, Mark Foster, Tim Schappe, BS, Ethan McClain, Michelle Becker-Hapak, BS, Melissa M Berrien-Elliott, PhD, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 3307.

https://doi.org/10.1182/blood-2019-126982

Published: 2019

Journal Articles

T-Cell Reconstitution after Unrelated Donor HSCT Using Immunotherapy with CD25/71 Allodepleted Donor T Cells: Results of the Randomised Icat Study

Blood (2019) 134 (Supplement_1): 1995.

https://doi.org/10.1182/blood-2019-124404

Published: 2019

Journal Articles

CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity

Tim Sauer, MD, Kathan Parikh, Sandhya Sharma, Bilal Omer, MD, Stephen Gottschalk, MD, Cliona M. Rooney, PhD

Blood (2019) 134 (Supplement_1): 1932.

https://doi.org/10.1182/blood-2019-125534

Published: 2019

Journal Articles

Influence of CD27 - CD28 - T-Cells on the Therapeutic Outcome in Adult Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma after CART-Infusion

Nina Worel, MD, Katharina Pfistershammer, Winfried Pickl, Marion Heinz, RN, MPhil, Martina Schlager, Beate Pribitzer, Andreas Tanzmann, MD, Ulrich Jaeger, MD, Georg Hopfinger

Blood (2019) 134 (Supplement_1): 1935.

https://doi.org/10.1182/blood-2019-126191

Published: 2019

Journal Articles

Prophylactic Itacitinib (INCB039110) for the Prevention of Cytokine Release Syndrome Induced By Chimeric Antigen Receptor T-Cells (CAR-T-cells) Therapy

Eduardo Huarte, PhD, Roddy S O'Connor, PhD, Melissa Parker, Taisheng Huang, Michael C. Milone, Paul Smith

Blood (2019) 134 (Supplement_1): 1934.

https://doi.org/10.1182/blood-2019-128288

Published: 2019

NARROW

MYC Oncogene Abrogates Natural Killer (NK) Cell-Mediated Immune Surveillance of B- and T- Lymphoid Malignancies By Suppressing STAT1/2-Type I IFN Signaling

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Enhancing Anti-Tumor Immunity and Responses to Immune Checkpoint Blockade By Suppressing Interleukin-10 in Chronic Lymphocytic Leukemia

Eomes and IL-10 Regulate Anti-Tumor Activity of T Cells in Chronic Lymphocytic Leukemia

Telomere Shortening By Terc Knockout in the Eµ-TCL1 Transgenic Murine Model of CLL: Characterization of Disease Development and Survival

Response to Bcma CAR-T Cells Correlates with Pretreatment Target Antigen Density and Is Improved By Small Molecule Inhibition of Gamma Secretase

Development of an Allogeneic Anti-Bcma T Cell Therapy Utilizing a Novel Dimeric Antigen Receptor (DAR) Structure

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies- Two-Year Follow-up of Multicenter Study in Singapore

Cytokine-Induced Memory-like (ML) NK Cells Persist for > 2 Months Following Adoptive Transfer into Leukemia Patients with a MHC-Compatible Hematopoietic Cell Transplant (HCT)

Treatment with Acalibrutinib, Ibrutinib and CD19 CAR T Cells Restore the Number of Granulocytic Myeloid Derived Supressor Cells in CLL-Bearing Mice

In Vitro and in Vivo Activity of Melflufen in Amyloidosis

Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation

T-Cell Reconstitution after Unrelated Donor HSCT Using Immunotherapy with CD25/71 Allodepleted Donor T Cells: Results of the Randomised Icat Study

CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity

Influence of CD27 - CD28 - T-Cells on the Therapeutic Outcome in Adult Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma after CART-Infusion

Prophylactic Itacitinib (INCB039110) for the Prevention of Cytokine Release Syndrome Induced By Chimeric Antigen Receptor T-Cells (CAR-T-cells) Therapy

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American Society of Hematology

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American Society of Hematology

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