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Journal Articles

JAK/STAT Inhibition Targets TP53 altered Primary Human Acute Myeloid Leukemia Stem Cells

Marie Lue Antony, PhD, Klara Noble-Orcutt, BS, MS, Yoonku Lee, MS, Oluwateniayo Ogunsan, Jeffrey Lee Jensen, MD PhD, Fiona He, MD, Zohar Sachs, MD PhD

Blood (2020) 136 (Supplement 1): 27–28.

https://doi.org/10.1182/blood-2020-142993

Published: 2020

Journal Articles

Clinical Value of Next Generation Sequencing in the Detection of Recurring Structural Rearrangements and Copy Number Abnormalities in Acute Myeloid Leukemia

Beth A Pitel, MS, Neeraj Sharma, PhD, Cinthya Zepeda-Mendoza, PhD, James B Smadbeck, PhD, Kathryn E. Pearce, MS, Stephanie A. Smoley, BA, Joselle Cook, MBBS, George Vasmatzis, PhD, Zohar Sachs, MD PhD, David S. Viswanatha, MD, Robert Jenkins, MD PhD, Xinjie Xu, PhD, Sheng Xiao, MD, Nicole Hoppman, PhD, Rhett P. Ketterling, MD, Jess Peterson, MD, Patricia Greipp, DO, Linda B Baughn, PhD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-139691

Published: 2020

Journal Articles

High Risk of Relapse with Intermediate Dose Cytarabine for Consolidation in Young Favorable Risk AML Patients Following Induction with 7+3

Bhaskar Kolla, MBBS, Nurul Aidah Abdul Halim, MBBS, Zohar Sachs, MD PhD, Erica D. Warlick, MD, Daniel J. Weisdorf, MD, Fiona He, MD, Lao Zhentang, MBBS, MRCP

Blood (2019) 134 (Supplement_1): 3432.

https://doi.org/10.1182/blood-2019-123306

Published: 2019

Journal Articles

Cell Type-Specific Effects of Crizotinib in Human Acute Myeloid Leukemia with TP53 Alterations

Marie Lue Antony, PhD, Klara Noble-Orcutt, Oluwateniayo Ogunsan, Fiona He, MD, Zohar Sachs, MD PhD

Blood (2019) 134 (Supplement_1): 2563.

https://doi.org/10.1182/blood-2019-130487

Published: 2019

Journal Articles

NRAS G12V -Mediated Self-Renewal Signaling in Self-Renewing AML Stem Cells.

Marie Lue Antony, PhD, Klara Noble-Orcutt, Karen Sachs, PhD, Anna Khoroshilov, Daniel Chang, Alexandria Hillesheim, Hesham Mohei, Merve Pamukcuoglu, MD, Christine Bergene, David A. Largaespada, PhD, Zohar Sachs, MD PhD

Blood (2018) 132 (Supplement 1): 2626.

https://doi.org/10.1182/blood-2018-99-119448

Published: 2018

Journal Articles

Single-Cell Transcriptional Profiling of Acute Myeloid Leukemia Identifies Prognostic Transcriptional Profiles at Diagnosis

Karen Sachs, PhD, Aaron Sarver, PhD, Klara Noble-Orcutt, Connor Navis, Alexandria Hillesheim, Ian Nykaza, Rebecca S. Larue, PhD, Conner Hansen, Nuri Temiz, Ngoc Ha, Michael A. Linden, MDPhD, David A. Largaespada, PhD, Zohar Sachs, MD PhD

Blood (2017) 130 (Supplement 1): 2704.

https://doi.org/10.1182/blood.V130.Suppl_1.2704.2704

Published: 2017

Journal Articles

Germline Calr Mutation and Thrombocytosis Presenting with Concomitant BCR-ABL1+ CML

Linda B. Baughn, PhD, Scott Gilles, MD, Elizabeth L. Courville, MD, Andrew C. Nelson, MD PhD, Zohar Sachs, MD PhD

Blood (2016) 128 (22): 5494.

https://doi.org/10.1182/blood.V128.22.5494.5494

Published: 2016

Journal Articles

Immunoproteasome Inhibition to Target AML with Activated RAS Pathways

Connor Navis, Klara Noble-Orcutt, Rebecca S LaRue, PhD, Conner Hansen, B.S., Ngoc Ha, B.S., Alexandria Hillesheim, Ryan Schulz, Do-Hyung Kim, David A Largaespada, PhD, Zohar Sachs, MD PhD

Blood (2016) 128 (22): 577.

https://doi.org/10.1182/blood.V128.22.577.577

Published: 2016

Journal Articles

Single-Cell Analysis Reveals Molecular Mechanisms of NRAS-Mediated Leukemia Stem Cell Self-Renewal in a Murine Model of AML

Rebecca S. Larue, PhD, Klara E Noble, B.S., Conner Hansen, B.S., Ngoc Ha, B.S., David A Largaespada, PhD, Zohar Sachs, MD PhD

Blood (2015) 126 (23): 3060.

https://doi.org/10.1182/blood.V126.23.3060.3060

Published: 2015

Journal Articles

Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia

Rebecca S. LaRue, PhD, Hanh Nguyen, Karen Sachs, Nurul Azyan Mohd Hassan, Ernesto Diaz-Flores, PhD, Susan K. Rathe, Aaron G. Sarver, Ph.D., Sean C. Bendall, Ngoc A. Ha, Miechaleen D. Diers, B.S., Garry P. Nolan, PhD, Kevin Shannon, MD, Zohar Sachs, MD, PhD, David A. Largaespada, PhD

Blood (2013) 122 (21): 819.

https://doi.org/10.1182/blood.V122.21.819.819

Published: 2013

Journal Articles

Relapse Prediction Post Allogeneic Hematopoietic Cell Transplant for Myelodysplastic Syndromes Is Not Improved with Use of the More Stringent Blast Percentage Categories in the Revised International Prognostic Scoring System

Leyla Shune, MD, Zohar Sachs, MD, PhD, Todd E. Defor, MS, Michelle Dolan, MD, Daniel J. Weisdorf, MD, Celalettin Ustun, MD, Erica D. Warlick, MD

Blood (2012) 120 (21): 2011.

https://doi.org/10.1182/blood.V120.21.2011.2011

Published: 2012

Journal Articles

Are IPSS-R and IPSS Cytogenetic Risk Stratification Informative At the Time of Allogeneic Hematopoietic Cell Transplantation?

Zohar Sachs, MD, PhD, Michelle Dollan, MD, Todd E De For, Phd, Leyla Shune, MD, Sarah Cooley, MD, Daniel J. Weisdorf, MD, Erica D. Warlick, MD, Celalettin Ustun

Blood (2012) 120 (21): 1400.

https://doi.org/10.1182/blood.V120.21.1400.1400

Published: 2012

Journal Articles

Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9 -Specified Gene Expression Signature

Zohar Sachs, MD, PhD, Hanh Nguyen, Nurul Azyan Mohd Hassan, Susan K Rathe, Karen Sachs, Ph. D., Ernesto Diaz-Flores, PhD, Sean C Bendall, PhD, Miechaleen D Diers, Garry P. Nolan, Ph. D., Kevin M. Shannon, MD, David A. Largaespada, PhD

Blood (2012) 120 (21): 5116.

https://doi.org/10.1182/blood.V120.21.5116.5116

Published: 2012

Journal Articles

Delineating Critical Effectors of Remission Induction in a Mouse Model of AML

Zohar Sachs, MD, PhD, Susan K. Rathe, Ernesto Diaz-Flores, PhD, Miechaleen D Diers, Kevin M. Shannon, MD, David A. Largaespada, PhD

Blood (2011) 118 (21): 5232.

https://doi.org/10.1182/blood.V118.21.5232.5232

Published: 2011

Journal Articles

Oncogene Withdrawal Selectively Alters Phosphoprotein States and Shifts Differentiation Status In Myeloid Leukemia Subpopulations

Zohar Sachs, MD, PhD, Ernesto Diaz-Flores, PhD, Miechaleen D Diers, Karen Sachs, Sean C Bendall, PhD, Harris G Fienberg, Susan K Rathe, Garry P. Nolan, Ph.D., Kevin Shannon, MD, David Largaespada, PhD

Blood (2010) 116 (21): 3160.

https://doi.org/10.1182/blood.V116.21.3160.3160

Published: 2010

NARROW

JAK/STAT Inhibition Targets TP53 altered Primary Human Acute Myeloid Leukemia Stem Cells

Clinical Value of Next Generation Sequencing in the Detection of Recurring Structural Rearrangements and Copy Number Abnormalities in Acute Myeloid Leukemia

High Risk of Relapse with Intermediate Dose Cytarabine for Consolidation in Young Favorable Risk AML Patients Following Induction with 7+3

Cell Type-Specific Effects of Crizotinib in Human Acute Myeloid Leukemia with TP53 Alterations

NRAS G12V -Mediated Self-Renewal Signaling in Self-Renewing AML Stem Cells.

Single-Cell Transcriptional Profiling of Acute Myeloid Leukemia Identifies Prognostic Transcriptional Profiles at Diagnosis

Germline Calr Mutation and Thrombocytosis Presenting with Concomitant BCR-ABL1+ CML

Immunoproteasome Inhibition to Target AML with Activated RAS Pathways

Single-Cell Analysis Reveals Molecular Mechanisms of NRAS-Mediated Leukemia Stem Cell Self-Renewal in a Murine Model of AML

Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia

Relapse Prediction Post Allogeneic Hematopoietic Cell Transplant for Myelodysplastic Syndromes Is Not Improved with Use of the More Stringent Blast Percentage Categories in the Revised International Prognostic Scoring System

Are IPSS-R and IPSS Cytogenetic Risk Stratification Informative At the Time of Allogeneic Hematopoietic Cell Transplantation?

Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9 -Specified Gene Expression Signature

Delineating Critical Effectors of Remission Induction in a Mouse Model of AML

Oncogene Withdrawal Selectively Alters Phosphoprotein States and Shifts Differentiation Status In Myeloid Leukemia Subpopulations

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American Society of Hematology

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ASH Publications

American Society of Hematology

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