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Yun Huang, PhD
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Journal Articles

Tet2 Inactivation Enhances the Anti-Tumor Activity of Tumor-Infiltrating Lymphocytes (TILs) to Curtail Melanoma Growth

Minjung Lee, PhD, Jianfang Li, PhD, Shaohai Fang, MS, Joanna Zhang, Anh Tran Tram Vo, Wei Han, MS, Hongxiang Zeng, PhD, Sevinj Isgandarova, Margarita Martinez Moczygemba, PhD, Yubin Zhou, PhD, Jia Li, PhD, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27.
https://doi.org/10.1182/blood-2020-137242
Published: 2020
Journal Articles

Highly-Sensitive DNA Hydroxymethylation Analysis in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, Hui Yang, MD PhD, Caleb Class, PhD, Stefan Siwko, Yubin Zhou, PhD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-137733
Published: 2020
Journal Articles

Tet2 Deficiency Rejuvenates Hematopoietic Stem and Progenitor Cells during Ageing

Tingting Hong, Shengli Li, PhD, Shaohai Fang, MS, Anna Guzman, Wei Han, MS, Yubin Zhou, PhD, Leng Han, PhD, Margaret Goodell, PhD, Yun Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37.
https://doi.org/10.1182/blood-2020-141705
Published: 2020
Journal Articles

Comprehensive DNA 5-Hydroxymethylation Landscapes in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, MS, Caleb Class, PhD, Hui Yang, PhDMD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2996.
https://doi.org/10.1182/blood-2019-128599
Published: 2019
Journal Articles

A Combination Strategy Targeting Enhancer Plasticity Exerts Synergistic Lethality Against Beti-Resistant Leukemia Cells

Lei Guo, PhD, Jia Li, PhD, Hongxiang Zeng, PhD, Anna Guzman, Tingting Li, MD, Minjung Lee, MS, Yubin Zhou, PhD, Clifford Stephan, Peter J.A Davies, Margaret Goodell, PhD, Deqiang Sun, PhD, Mark A. Dawson, PhD MBBS, Yun Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5053.
https://doi.org/10.1182/blood-2019-130586
Published: 2019
Journal Articles

Antibiotics Treatment Ameliorates TET2 Loss of Function Associated Hematological Malignancies

Hongxiang Zeng, PhD, Hailan He, MS, Jia Li, PhD, Wei Han, MS, Anna Guzman, Deqiang Sun, PhD, Katherine Y. King, MD PhD, Margaret A. Goodell, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2610.
https://doi.org/10.1182/blood-2018-99-116424
Published: 2018
Journal Articles

Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction

Shaohai Fang, MS, Yang Xiao, PhD, Jia Li, PhD, Tingting Li, MD, Hongxiang Zeng, PhD, Wei Han, MS, Yubin Zhou, PhD, Deqiang Sun, PhD, James M. Martin, MD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2394.
https://doi.org/10.1182/blood-2018-99-115358
Published: 2018
Journal Articles

Synthetic Lethality of Combinatory Inhibition of BET and CDK7 in BET(i) Resistant Leukemia Cells

Lei Guo, PhD, Jia Li, PhD, Shaohai Fang, MS, Minjung Lee, MS, Hongxiang Zeng, PhD, Tingting Li, MD, Wei Han, MS, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1354.
https://doi.org/10.1182/blood-2018-99-116634
Published: 2018
Journal Articles

Disruption of TET2 Dioxygenase Enhances Antitumor Efficiency in CD8+ Tumor Infiltrating Lymphocytes

Minjung Lee, MS, Hongxiang Zeng, PhD, Jia Li, PhD, Wei Han, MS, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 860.
https://doi.org/10.1182/blood-2018-99-115405
Published: 2018
Journal Articles

TCF3-Hlf Hijacks ERG to Activate Leukemia-Critical Super-Enhancers in t(17;19) Leukemia

Yun Huang, PhD, Brice Mouttet, Hans-Jörg Warnatz, PhD, Maria Pamela Dobay, PhD, Blerim Marovca, Silvia Jenni, PhD, Martin Schrappe, MD PhD, Martin Stanulla, MD PhD, Marie-Laure Yaspo, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 561.
https://doi.org/10.1182/blood.V130.Suppl_1.561.561
Published: 2017
Journal Articles

Dnmt3a and Tet2 interact to Repress differentiation lineage-specific transcriptional factors in Hematopoietic Stem Cells By the Regulation of Epigenome

Xiaotian Zhang, BS, Mira Jeong, PhD, Jianzhong Su, Myung Gon Ko, PhD, Yun Huang, PhD, Hyun Jung Park, Anjana Rao, PhD, Wei Li, PhD, Margaret A. Goodell, PhD
Journal: Blood
Blood (2014) 124 (21): 242.
https://doi.org/10.1182/blood.V124.21.242.242
Published: 2014
Journal Articles

Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a

Mira Jeong, Ph.D., Deqiang Sun, Min Luo, Ph.D., Yun Huang, PhD, Myunggon Ko, PhD, Lucas Chavez, Grant A Challen, PhD, Benjamin Rodriguez, Xiaotian Zhang, B.S, Liubin Yang, Hui Wang, Ph.D., Rui Chen, Ph.D., Rebecca Hannah, Ph.D., Sang-Bae Kim, Ju-Seog Lee, Berthold Gottgens, Ph.D., Preethi Gunaratne, Lucy A Godley, Gretchen Darlington, Ph.D., Anjana Rao, PhD, Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2013) 122 (21): 2406.
https://doi.org/10.1182/blood.V122.21.2406.2406
Published: 2013
Journal Articles

TET2: Mechanism and Functional Consequences of Hydroxymethylation

Anjana Rao, PhD, Myunggon Ko, PhD, William Pastor, Yun Huang, PhD
Journal: Blood
Blood (2011) 118 (21): SCI-32.
https://doi.org/10.1182/blood.V118.21.SCI-32.SCI-32
Published: 2011
Journal Articles

Mechanisms of Defective Hydroxylation of 5-Methylcytosine in MDS Include Pathways Other Than TET2 and IDH1/2

Anna M Jankowska, PhD, Yun Huang, PhD, Myunggon Ko, PhD, Utz J Pape, PhD, Hideki Makishima, MD, PhD, Hadrian Szpurka, PhD, Fabiola Traina, MD, PhD, Valeria Visconte, PhD, Ramon V Tiu, MD, Mikkael A Sekeres, MD, Anjana Rao, PhD, Jaroslaw P Maciejewski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 462.
https://doi.org/10.1182/blood.V118.21.462.462
Published: 2011