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Journal Articles

IL-33 Induces Paneth Cell Production of EGF and Soluble ST2, Regulating Epithelial Regeneration after Intestinal Injury

Marco Calafiore, YA-Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Chang, Suze Jansen, Anastasiya Egorova, Shuichiro Takashima, Jason Kuttiyara, Takahiro Ito, Jonathan Serody, Susumu Nakae, Heth Turnquist, Johan van Es, Hans Clevers, Caroline A. Lindemans, Bruce R Blazar, Alan M. Hanash

Blood (2023) 142 (Supplement 1): 346.

https://doi.org/10.1182/blood-2023-191189

Published: 2023

Journal Articles

Donor-Derived Amphiregulin Drives CD4 + T Cell Expansion and Promotes Tissue Pathology after Experimental Allogeneic BMT

Takahiro Ito, Shuichiro Takashima, Marco Calafiore, Ya-Yuan Fu, Anastasiya Egorova, Jason Kuttiyara, Winston Chang, Paola Vinci, Viktor Arnhold, Dietmar Zaiss, Alan M. Hanash

Blood (2022) 140 (Supplement 1): 1152–1153.

https://doi.org/10.1182/blood-2022-168793

Published: 2022

Journal Articles

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Shuichiro Takashima, MD PhD, Maria L. Martin, PhD, Suze A. Jansen, Ya-Yuan Fu, PhD, Anastasiya Egorova, Chen Liu, MD PhD, Richard Kolesnick, MD, Caroline A. Lindemans, MD, Alan M. Hanash, MD PhD

Blood (2019) 134 (Supplement_1): 585.

https://doi.org/10.1182/blood-2019-130811

Published: 2019

Journal Articles

Nrf2 regulates CD4 + T cell–induced acute graft-versus-host disease in mice

Blood (2018) 132 (26): 2763–2774.

https://doi.org/10.1182/blood-2017-10-812941

Published: 2018

Includes: Supplemental data

Journal Articles

Nrf2 Is a Critical Mediator of CD4 T Cell-Induced Acute Graft-Versus-Host Disease

Jennifer Tsai, MD PhD, Enrico Velardi, PhD BS, Yusuke Shono, MD PhD, Kimon Argyropoulos, MD, Odette M. Smith, BA, Amina Lazrak, BS, Chen Liu, MD PhD, George F Murphy, MD, Ya-Yuan Fu, PhD, Alan M. Hanash, Robert R. Jenq, MD, Jarrod A Dudakov, PhD, Marcel R.M. van den Brink, MD PhD

Blood (2017) 130 (Supplement 1): 205.

https://doi.org/10.1182/blood.V130.Suppl_1.205.205

Published: 2017

Journal Articles

High Expression of Lymphoid Enhancer-Binding Factor 1 ( LEF1 ) Is Related to Ummutated Status of Igvh and Is an Unfavorable Prognostic Marker for Aggressive CLL Patients

Wei Wu, Huayuan Zhu, Yuan Fu, Jiadai Xu, Wenyi Shen, Wei Xu, MD, PhD, Peng Liu, Jianyong Li, MD, PhD

Blood (2012) 120 (21): 4573.

https://doi.org/10.1182/blood.V120.21.4573.4573

Published: 2012

Journal Articles

The Expression of LEF1 Gene and its Clinical Significance in Chinese Patients with Acute Myeloid Leukemia

Yuan Fu, Huayuan Zhu, Wei Wu, Jiadai Xu, Wenyi Shen, Wei Xu, MD, PhD, Peng Liu, Jianyong Li, MD, PhD

Blood (2012) 120 (21): 4621.

https://doi.org/10.1182/blood.V120.21.4621.4621

Published: 2012

Journal Articles

Mouse hematopoietic cell–targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging–like phenotype

Charlie Mantel, Steven Messina-Graham, Akira Moh, Scott Cooper, Giao Hangoc, Xin-Yuan Fu, Hal E. Broxmeyer

Blood (2012) 120 (13): 2589–2599.

https://doi.org/10.1182/blood-2012-01-404004

Published: 2012

Includes: Supplemental data

Journal Articles

STAT3 Is Required for Notch-Induced Leukemogenesis, and Functions As a Critical Survival Effector in T-Cell Leukemia

Jixin Ding, PhD, Ana L. Batista, PhD, Sonia Rodriguez-Rodriguez, PhD, Lin Wang, PhD, Wenjun Zhang, PhD, Akira Moh, PhD, Xin-Yuan Fu, PhD, Weinian Shou, PhD, Nadia Carlesso, MD, PhD, Angelo A Cardoso, MD, PhD

Blood (2011) 118 (21): 920.

https://doi.org/10.1182/blood.V118.21.920.920

Published: 2011

Journal Articles

STAT3 Deletion In Hematopoietic Tissue Causes Mitochondrial Dysfunction with Increased ROS Leading to LT-Repopulating Stem Cell Depletion, Erythroid Dysplasia, Peripheral Neutrophilia, and a Rapid Aging-Like Phenotype.

Charlie Mantel, Steve Messina-Graham, Akira Moh, PhD, Xin-Yuan Fu, PhD, Hal E. Broxmeyer, PhD

Blood (2010) 116 (21): 2621.

https://doi.org/10.1182/blood.V116.21.2621.2621

Published: 2010

Journal Articles

The Earliest Stages of Loss of Stem Cell Self-Renewal in-Vivo Is Linked to Upregulated Biosynthesis of “Quiet” Mitochondria and Is Influenced by CXCR4 Activation and STAT3 Gene Deletion.

Charlie Mantel, Steven Messina-Graham, Akira Moh, PhD, Xin-Yuan Fu, PhD, Hal E. Broxmeyer, PhD

Blood (2009) 114 (22): 2546.

https://doi.org/10.1182/blood.V114.22.2546.2546

Published: 2009

Journal Articles

Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3

Seiji Fukuda, Pratibha Singh, Akira Moh, Mariko Abe, Edward M. Conway, H. Scott Boswell, Seiji Yamaguchi, Xin-Yuan Fu, Louis M. Pelus

Blood (2009) 114 (2): 394–403.

https://doi.org/10.1182/blood-2008-11-188714

Published: 2009

Includes: Supplemental data

Journal Articles

STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34 pos cells into tumor-competent dendritic cells

Peter A. Cohen, Gary K. Koski, Brian J. Czerniecki, Kevin D. Bunting, Xin-Yuan Fu, Zhengqi Wang, Wen-Jun Zhang, Charles S. Carter, Mohamed Awad, Christopher A. Distel, Hassan Nagem, Christopher C. Paustian, Terrence D. Johnson, John F. Tisdale, Suyu Shu

Blood (2008) 112 (5): 1832–1843.

https://doi.org/10.1182/blood-2007-12-130138

Published: 2008

Includes: Supplemental data

Journal Articles

STAT3 Deletion after Birth Results in Marked Decreases in Absolute Numbers and Cell Cycling Status of Marrow and Spleen Myeloid Progenitor Cells, and STAT3 Is a Critical Molecule in Mediating Synergistically Stimulated Progenitor Cell Proliferation.

Hal E. Broxmeyer, PhD, Scott Cooper, BSc, Giao Hangoc, DVM, Wenjun Zhang, PhD, Akira Moh, PhD, Thomas Welte, PhD, Xin-Yuan Fu, PhD

Blood (2005) 106 (11): 1346.

https://doi.org/10.1182/blood.V106.11.1346.1346

Published: 2005

NARROW

IL-33 Induces Paneth Cell Production of EGF and Soluble ST2, Regulating Epithelial Regeneration after Intestinal Injury

Donor-Derived Amphiregulin Drives CD4 + T Cell Expansion and Promotes Tissue Pathology after Experimental Allogeneic BMT

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Nrf2 regulates CD4 + T cell–induced acute graft-versus-host disease in mice

Nrf2 Is a Critical Mediator of CD4 T Cell-Induced Acute Graft-Versus-Host Disease

High Expression of Lymphoid Enhancer-Binding Factor 1 ( LEF1 ) Is Related to Ummutated Status of Igvh and Is an Unfavorable Prognostic Marker for Aggressive CLL Patients

The Expression of LEF1 Gene and its Clinical Significance in Chinese Patients with Acute Myeloid Leukemia

Mouse hematopoietic cell–targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging–like phenotype

STAT3 Is Required for Notch-Induced Leukemogenesis, and Functions As a Critical Survival Effector in T-Cell Leukemia

STAT3 Deletion In Hematopoietic Tissue Causes Mitochondrial Dysfunction with Increased ROS Leading to LT-Repopulating Stem Cell Depletion, Erythroid Dysplasia, Peripheral Neutrophilia, and a Rapid Aging-Like Phenotype.

The Earliest Stages of Loss of Stem Cell Self-Renewal in-Vivo Is Linked to Upregulated Biosynthesis of “Quiet” Mitochondria and Is Influenced by CXCR4 Activation and STAT3 Gene Deletion.

Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3

STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34 pos cells into tumor-competent dendritic cells

STAT3 Deletion after Birth Results in Marked Decreases in Absolute Numbers and Cell Cycling Status of Marrow and Spleen Myeloid Progenitor Cells, and STAT3 Is a Critical Molecule in Mediating Synergistically Stimulated Progenitor Cell Proliferation.

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American Society of Hematology

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American Society of Hematology

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