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Journal Articles

Inhibition of MRP1 Induces Fetal Hemoglobin through NRF2 Activation to Protect Human Erythroid Cells from Sickling

Yannis Hara, Emily Kawabata, Viktor T. Lemgart, Paola G. Bronson, Alexandra Hicks, Sriram Krishnamoorthy, Nicholas Watkins, Robert Peters, David J. Roberts, Emanuele Di Angelantonio, John Danesh, William Astle, Dirk S. Paul, Samuel Lessard, Adam S. Butterworth

Blood (2022) 140 (Supplement 1): 952–953.

https://doi.org/10.1182/blood-2022-168169

Published: 2022

Journal Articles

SGK1 Inhibition Induces Fetal Hemoglobin in Erythroid Cells

Yannis Hara, Mark Stottlemyer, Kim Alving, Nis Halland, Alexandra Hicks, David R. Light

Blood (2021) 138 (Supplement 1): 963.

https://doi.org/10.1182/blood-2021-146071

Published: 2021

Journal Articles

Heme-Regulated eIF2α Kinase (HRI) Inhibition Decreases PKR Activation in HUDEP2 Cells

Yannis Hara, Dipti Gupta, Courtney Mercadante, Kim Alving, Yukio Nakamura, Sriram Krishnamoorthy, Alexandra Hicks, Melanie Demers

Blood (2021) 138 (Supplement 1): 2035.

https://doi.org/10.1182/blood-2021-144679

Published: 2021

Journal Articles

Catalytic Activity of Heme-Regulated eIF2 Alpha Kinase (HRI) Regulates Fetal Hemoglobin

Dipti Gupta, Yannis Hara, PhD, Samuel Lessard, PhD, Sarah Sturtevant, BSc, Yukio Nakamura, MD PhD, Sriram Krishnamoorthy, PhD, Melanie Demers, PhD, Alexandra Hicks, PhD

Blood (2020) 136 (Supplement 1): 7.

https://doi.org/10.1182/blood-2020-139991

Published: 2020