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Yangbing Zhao, PhD MD
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Journal Articles

First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma

Edward A. Stadtmauer, MD FACP, Adam D. Cohen, MD, Kristy Weber, MD, Simon F Lacey, PhD, Vanessa E. Gonzalez, J. Joseph Melenhorst, PhD, Joseph A Fraietta, PhD, Gabriela Plesa, MD, Joanne Shea, Tina Matlawski, RN, Amanda Cervini, RN, Patricia Mangan, CRNP, Avery Gaymon, Stephanie Desjardins, Eric Lancaster, MD, January Salas-Mckee, Megan M. Suhoski, PhD, Andrew Fesnak, MD, Matthew O'Rourke, Anne Lamontagne, Don L. Siegel, MD PhD, Regina M Young, PhD, Anne Chew, PhD, Christopher L Nobles, PhD, Frederic D. Bushman, PhD, Howard Y. Chang, MD PhD, Ansuman T. Satpathy, MD PhD, Yangbing Zhao, PhD MD, Wei-Ting Hwang, PhD, Elizabeth O. Hexner, MDMS, Carl H June, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 49.
https://doi.org/10.1182/blood-2019-122374
Published: 2019
Journal Articles

Clinical Evidence That Deficiency of the Methylcytosine Dioxygenase TET2 Gene Promotes the Clonal Expansion and Therapeutic Efficacy of CD19-Directed T Cells

Joseph A Fraietta, PhD, Christopher L Nobles, PhD, Morgan A Sammons, PhD, Shannon A. Carty, MD, Stefan M Lundh, BS, Tyler Reich, Alexandria P Cogdill, BS, MB, Mercy Gohil, Jennifer J.D. Morrissette, PhD, Irina Kulikovskaya, Farzana Nazimuddin, MS, Minnal Gupta, Yan Wang, PhD, Xiaojun Liu, Regina M Young, PhD, David E Ambrose, Martha S Jordan, PhD, Katherine T Marcucci, PhD, Bruce L Levine, PhD, Yangbing Zhao, PhD MD, Michael Kalos, PhD, David L Porter, MD, Simon F Lacey, PhD BS, Shelley L Berger, PhD BS, Frederic D Bushman, PhD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1909.
https://doi.org/10.1182/blood.V130.Suppl_1.1909.1909
Published: 2017
Journal Articles

A Novel Small Animal Model to Test on-Target Off-Tumor Cytoxicity of Adoptive Immune Therapies

Mauro Castellarin, PhD, Joseph A. Fraietta, PhD, Jihyun Lee, PhD, John Scholler, Yangbing Zhao, PhD MD, Carl H. June, MD
Journal: Blood
Blood (2015) 126 (23): 5432.
https://doi.org/10.1182/blood.V126.23.5432.5432
Published: 2015
Journal Articles

Improved Anti-Leukemia Activities of Adoptively Transferred T Cells Expressing Bites

Xiaojun Liu, Master, David M. Barrett, MD PhD, Shuguang Jiang, PhD, Chongyun Fang, PhD, Stephan A. Grupp, MD PhD, Carl H. June, MD, Yangbing Zhao, PhD MD
Journal: Blood
Blood (2015) 126 (23): 4431.
https://doi.org/10.1182/blood.V126.23.4431.4431
Published: 2015
Journal Articles

Multiplex Cripsr/Cas9 Genome Editing to Generate Potent Universal CART and PD1-Deficient Cells Against Leukemia

Jiangtao Ren, PhD, Xiaojun Liu, Master, Chongyun Fang, PhD, Shuguang Jiang, PhD, Carl H. June, MD, Yangbing Zhao, PhD MD
Journal: Blood
Blood (2015) 126 (23): 4280.
https://doi.org/10.1182/blood.V126.23.4280.4280
Published: 2015