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Xinrui Yuan
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Journal Articles

Targeting Poly(U) Binding Splicing Factor 60 (PUF60): A Small-Molecule Inhibitor Shows Anti-Leukemic Activity and Impacts Cell Cycle in Leukemia Models

Xinrui Yuan, Mona Kazemi Sabzvar, Amol D Patil, Arda Durmaz, Jaroslaw Maciejewski, Valeria Visconte, Chao-Yie Yang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7470.
https://doi.org/10.1182/blood-2024-210241
Published: 2024
Journal Articles

Small-Molecule U2 Auxiliary Factor Homology Motif (UHM) Domain Inhibitors Cause Splicing Pattern Changes in U2AF1 Mutant Leukemia Cells and Induce Sub-G1 Cell Cycle Arrest

Chao-Yie Yang, Xinrui Yuan, Mona Kazemi Sabzvar, Arda Durmaz, Krishnapriya Chinnaswamy, Jeanne Stuckey, Seth J Corey, Jaroslaw P. Maciejewski, Valeria Visconte
Journal: Blood
Blood (2023) 142 (Supplement 1): 115.
https://doi.org/10.1182/blood-2023-190365
Published: 2023
Journal Articles

Novel Chemical Series of Anti-ST2 Small Molecules Suppress Allogeneic T Cells Proliferation While Increasing Treg Cells and Improve Gvhd and Survival In Vivo

Chao-Yie Yang, Xinrui Yuan, Hua Jiang, Jason C. Rech, Denggang Fu, Aaron Robida, Krishani Rajanayake, Hebao Yuan, Bo Wen, Duxin Sun, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Sophie Paczesny
Journal: Blood
Blood (2022) 140 (Supplement 1): 10675–10677.
https://doi.org/10.1182/blood-2022-163374
Published: 2022