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Journal Articles

The Treatment Pathways, Patient Characteristics and Outcomes in Patients with CD30-Expressing Lymphoma from China: A Multi-Center, Non-Interventional, Retrospective Study

Yi Miao, Wenyu Li, Kaiyang Ding, Fei Li, Xiaojing Yan, Xiaoxi Zhou, Caixia Li, Guohui Cui, Liqun Zou, Bing Xiu, Xiangxiang Zhou, Liansheng Zhang, Fuling Zhou, Hongmei Jing, Jianli Wang, Ziheng Guo, Jianyong Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 6372.
https://doi.org/10.1182/blood-2024-201339
Published: 2024
Journal Articles

Tandem CD19/20 CAR-T Showed Durable Efficacy in Patients with Relapsed/Refractory B-Cell Lymphoma: Interim Results from a Multicenter Phase I/II Trial

Jia Wei, Xiaoxi Zhou, Hui Luo, Yang Cao, Jiaqi Guo, Jie Zhao, Lifang Huang, Ang Zhang, Lihong Liu, Weiwei Tian, Yicheng Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3132.
https://doi.org/10.1182/blood-2024-205207
Published: 2024
Journal Articles

Study of PC-002 (Sepantronium Bromide), a First-in-Class Inhibitor of Deubiquitinases (DUBs) Targeting Myc Degradation in Relapsed/Refractory c-Myc Rearranged High-Grade B Cell Lymphoma (HGBCL): Updated Phase 2 Results

Sung-Soo Yoon, Zhiming Li, Seokjin Kim, Ki-Seong Eom, Keshu Zhou, Sung-Nam Lim, Xiaoxi Zhou, Ye Guo, Sung Yong Oh, Huilai Zhang, Hagop Youssoufian, Vernon Jiang, Zanchun Huang, Georgina Kilfoil, Xin Wang, Zhixiang Cao, Xiang LI, Yihai Lin, Alexander Wu, Yiyou Chen, Yuqin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 3120.
https://doi.org/10.1182/blood-2024-206700
Published: 2024
Journal Articles

A Phase 2 Clinical Trial of Anti-CD19 CAR-T (pCAR-19B) in Chinese Pediatric and Young Adult with Relapsed/Refractory (R/R) CD19+ B-ALL: The First Pivotal Study in an Asian Population

Ruidong Zhang, Yang Cao, Xiaofan Zhu, Zhenya Hong, Jianwen Xiao, Fei Li, Ju Gao, Hongling Peng, Yongmin Tang, Runming Jin, Sixi Liu, Yajuan Cui, Shaoyan Hu, Min Yu, Xiaojun Xu, Xiaoyan Wu, Xiaoxi Lu, Huirong Mai, Xiaoxi Zhou, Yingzi Zhang, Zhi Yang, Yufeng Huang, Xiao He, Liang Huang, Cheng Qian, Yicheng Zhang, Tianyou Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4205.
https://doi.org/10.1182/blood-2024-206408
Published: 2024
Journal Articles

Phase 1 Dose Escalation Study of the Anti-CD7 CAR-T Therapy in Relapsed/Refractory T-Cell Acute Leukemia and Lymphoblastic Lymphoma

Jiali Cheng, Jue Wang, Xia Mao, Wei Mu, Shijia Sun, Xiaoxi Zhou, Liang Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6863.
https://doi.org/10.1182/blood-2023-184370
Published: 2023
Journal Articles

Functional Diversification and Dynamics of CAR-T Cells in B-ALL Patients

Zongcheng Li, Lei Zhao, Yuanyuan Zhang, Li Zhu, Wei Mu, Tong Ge, Jin Jin, Jiaqi Tan, Jiali Cheng, Jue Wang, Na Wang, Xiaoxi Zhou, Liting Chen, Zhilin Chang, Chen Liu, Bian Zhilei, Bing Liu, Lilin Ye, Yu Lan, Liang Huang, Jianfeng Zhou
Journal: Blood
Blood (2023) 142 (Supplement 1): 4851.
https://doi.org/10.1182/blood-2023-178624
Published: 2023
Journal Articles

CD19/CD22 CAR T-Cell Therapy Following Autologous Transplantation Is an Optimizing Strategy in Relapsed/Refractory Central Nervous System Lymphoma

Qiuxia Yu, Daizi Gang, Jue Wang, Liang Huang, Chunrui Li, Yicheng Zhang, Xiaoxi Zhou, Yang Cao
Journal: Blood
Blood (2023) 142 (Supplement 1): 6855.
https://doi.org/10.1182/blood-2023-180363
Published: 2023
Journal Articles

Treatment of Relapsed/Refractory Hgbcl and Bukitt's Lymphoma with c-Myc Rearrangement: A Multi-Center, Open-Label, Phase 2 Study of PC-002 (SepB), a First-in-Class Deubiquitinase Inhibitor Inducing Myc Degradation

Sung-Soo Yoon, Zhiming Li, Keshu Zhou, Xiaoxi Zhou, Ye Guo, Huilai Zhang, Ki-Seong Eom, Seok Jin Kim, Sung Yong Oh, Sung-Nam Lim, Hagop Youssoufian, Vernon Jiang, Zhanchun Huang, Georgina Kilfoil, Xin Wang, Zhixiang Cao, Xiang LI, Yihai Lin, Alexander Wu, Yiyou Chen, Yuqin Song
Journal: Blood
Blood (2023) 142 (Supplement 1): 1754.
https://doi.org/10.1182/blood-2023-190995
Published: 2023
Journal Articles

MIP3α As an Early Prognostic Predictor for Patients with B-Cell Malignancies Receiving CD19/CD22-Redirected CAR T-Cell Cocktail Therapy

Jin Jin, Jiali Cheng, Na Wang, Liang Huang, Xiaoxi Zhou, Liting Chen, Hui Luo, Tianjiao Liu, Jiao Meng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10265–10266.
https://doi.org/10.1182/blood-2022-156710
Published: 2022
Journal Articles

The Safety and Efficacy of p CAR-19B, a Scfv Humanlized CD19-Directed CAR-T for Patients with Relapsed/Refactory (R/R) CD19+ B-ALL

Zhenya Hong, Zhi Yang, Xiaoxi Zhou, Gaoxiang Wang, Mi Zhou, Yingzi Zhang, Peiling Zhang, Jinjin Huang, Li Meng, Haitao Ruan, Min Xiao, Yunyan Li, Linling Wang, Meiling Wang, Wei Zhu, Qianzhen Zhang, Junjie Shen, Jianfeng Zhou, Cheng Qian, Liang Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 4625–4626.
https://doi.org/10.1182/blood-2022-162134
Published: 2022
Journal Articles

A phase 1 study of a novel fully human BCMA-targeting CAR (CT103A) in patients with relapsed/refractory multiple myeloma

Clinical Trials & Observations
Di Wang, Jue Wang, Guang Hu, Wen Wang, Yi Xiao, Haodong Cai, Lijun Jiang, Li Meng, Yongkun Yang, Xiaoxi Zhou, Zhenya Hong, Zheng Yao, Min Xiao, Liting Chen, Xia Mao, Li Zhu, Jin Wang, Lugui Qiu, Chunrui Li, Jianfeng Zhou
Journal: Blood
Blood (2021) 137 (21): 2890–2901.
https://doi.org/10.1182/blood.2020008936
Published: 2021
Includes: Supplemental data
Journal Articles

CD19/CD22 CAR-T Cell Cocktail Therapy Following Autologous Transplantation in Patients with Relapsed/Refractory B-Cell Lymphomas

Yang Cao, Yi Xiao, Na Wang, MD PhD, Gaoxiang Wang, MDPhD, Xiaoxi Zhou, MDPhD, Liang Huang, MD, Liting Chen, PhD, Min Xiao, MD PhD, Tongcun Zhang, PhD, Yicheng Zhang, Jianfeng Zhou, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11.
https://doi.org/10.1182/blood-2020-140308
Published: 2020
Journal Articles

Efficacy and safety of CAR19/22 T-cell cocktail therapy in patients with refractory/relapsed B-cell malignancies

Clinical Trials & Observations
Na Wang, Xuelian Hu, Wenyue Cao, Chunrui Li, Yi Xiao, Yang Cao, Chaojiang Gu, Shangkun Zhang, Liting Chen, Jiali Cheng, Gaoxiang Wang, Xiaoxi Zhou, Miao Zheng, Xia Mao, Lijun Jiang, Di Wang, Qiuxiang Wang, Yaoyao Lou, Haodong Cai, Dandan Yan, Yicheng Zhang, Tongcun Zhang, Jianfeng Zhou, Liang Huang
Journal: Blood
Blood (2020) 135 (1): 17–27.
https://doi.org/10.1182/blood.2019000017
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Fully Human Bcma Targeting CAR T Cell Therapy in Relapsed/Refractory Multiple Myeloma

Chunrui Li, MD PhD, Jue Wang, MD PhD, Di Wang, MD PhD, Guang Hu, Yongkun Yang, Xiaoxi Zhou, MD PhD, Li Meng, MD PhD, Zhenya Hong, MD PhD, Liting Chen, PhD, Xia Mao, MD PhD, Min Xiao, MD PhD, Jianfeng Zhou, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 929.
https://doi.org/10.1182/blood-2019-128468
Published: 2019
Journal Articles

CAR22/19 Cocktail Therapy for Patients with Refractory/Relapsed B-Cell Malignancies

Liang Huang, MDPhD, Na Wang, MD PhD, Yang Cao, Chunrui Li, MDPhD, Yi Xiao, MD PhD, Min Xiao, MD PhD, Xiaoxi Zhou, MD, PhD, Gaoxiang Wang, MDPhD, Zhenya Hong, MD, PhD, Miao Zhen, MD, PhD, Weixu Meng, MD PhD, Bin Zhang, PhD, Yicheng Zhang, MDPhD, Guido Marcucci, Tongcun Zhang, PhD, Jianfeng Zhou, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1408.
https://doi.org/10.1182/blood-2018-99-113714
Published: 2018
Journal Articles

Transmembrane TNF-α preferentially expressed by leukemia stem cells and blasts is a potent target for antibody therapy

Xiaoxi Zhou, Shiqiu Zhou, Baihua Li, Qinlu Li, Lili Gao, Dan Li, Quan Gong, Li Zhu, Jue Wang, Na Wang, Liang Huang, Lei Zhao, Zhuoya Li, Jianfeng Zhou
Journal: Blood
Blood (2015) 126 (12): 1433–1442.
https://doi.org/10.1182/blood-2015-01-624833
Published: 2015
Includes: Supplemental data