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Journal Articles

Improving CAR-T Cell Function through a Targeted Cytokine Delivery System Utilizing CAR Target-Modified Extracellular Vesicles

Yuanyuan Zhang, Meijuan Huang, Tianjiao Liu, Yuhang Cheng, Dengju Li, Yang Cao, Wei Mu, Liting Chen, Li Zhu, Tongjuan Li, Liang Huang, Jia Wei, Lei Zhao, Jue Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3419.
https://doi.org/10.1182/blood-2024-206731
Published: 2024
Journal Articles

Prediction of Organs Toxicity during CAR T-Cell Therapy By Using Cell-Free DNA Markers

Liting Chen, Qiyang Han, Yan Zhang, Guodan Zeng, Yuekun Fang, Man Zhang, Jia Wei, Yicheng Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4782.
https://doi.org/10.1182/blood-2024-194685
Published: 2024
Journal Articles

3D Live Imaging and Phenotyping of the Subcellular Cytotoxicity in CAR-T Cell Immunotherapy

Liting Chen, Zhaofei Wang, Jie Wang, Jin Jin, Jia Wei, Yicheng Zhang, Peng Fei
Journal: Blood
Blood (2024) 144 (Supplement 1): 4781.
https://doi.org/10.1182/blood-2024-193597
Published: 2024
Journal Articles

Reflecting In Vivo Spatio-Temporal Distribution Characteristics of CAR-T Cells through Real-World Clinical Samples

Man Zhang, Liting Chen, Caixia Chen, Jia Wei, Yicheng Zhang, Yi Xiao
Journal: Blood
Blood (2024) 144 (Supplement 1): 7125.
https://doi.org/10.1182/blood-2024-194628
Published: 2024
Journal Articles

Soluble PD-L1 Predicts Poor Outcome and Disease Progression in Patients with De Novo Myelodysplastic Syndromes

Xingcheng Yang, Xiaoying Zhang, Juan Peng, Lifang Huang, Shaolong He, Zhiqiong Wang, Liting Chen, Chunrui Li, Ling Ma, Jia Wei
Journal: Blood
Blood (2023) 142 (Supplement 1): 6448.
https://doi.org/10.1182/blood-2023-190744
Published: 2023
Journal Articles

Functional Diversification and Dynamics of CAR-T Cells in B-ALL Patients

Zongcheng Li, Lei Zhao, Yuanyuan Zhang, Li Zhu, Wei Mu, Tong Ge, Jin Jin, Jiaqi Tan, Jiali Cheng, Jue Wang, Na Wang, Xiaoxi Zhou, Liting Chen, Zhilin Chang, Chen Liu, Bian Zhilei, Bing Liu, Lilin Ye, Yu Lan, Liang Huang, Jianfeng Zhou
Journal: Blood
Blood (2023) 142 (Supplement 1): 4851.
https://doi.org/10.1182/blood-2023-178624
Published: 2023
Journal Articles

MIP3α As an Early Prognostic Predictor for Patients with B-Cell Malignancies Receiving CD19/CD22-Redirected CAR T-Cell Cocktail Therapy

Jin Jin, Jiali Cheng, Na Wang, Liang Huang, Xiaoxi Zhou, Liting Chen, Hui Luo, Tianjiao Liu, Jiao Meng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10265–10266.
https://doi.org/10.1182/blood-2022-156710
Published: 2022
Journal Articles

Updated Results of Fumanba-1: A Phase 1b/2 Study of a Novel Fully Human B-Cell Maturation Antigen-Specific CAR T Cells (CT103A) in Patients with Relapsed and/or Refractory Multiple Myeloma

Chunrui Li, Di Wang, Baijun Fang, Yongping Song, He Huang, Jianyong Li, Dehui Zou, Bing Chen, Jing Liu, Yujun Dong, Hanyun Ren, Kai Hu, Peng Liu, Xi Zhang, Jian-Qing Mi, Zhenyu Li, Kaiyang Ding, Jue Wang, Liting Chen, Aining Xu, Songbai Cai, Jingwen Zeng, Jingjing Guo, Hongyu Gui, Wen Wang, Lugui Qiu
Journal: Blood
Blood (2022) 140 (Supplement 1): 7435–7436.
https://doi.org/10.1182/blood-2022-166465
Published: 2022
Journal Articles

A Phase 1/2 Study of a Novel Fully Human B-Cell Maturation Antigen-Specific CAR T Cells (CT103A) in Patients with Relapsed and/or Refractory Multiple Myeloma

Chunrui Li, Di Wang, Yongping Song, Jianyong Li, He Huang, Bing Chen, Jing Liu, Kai Hu, Hanyun Ren, Xi Zhang, Zhenyu Li, Dehui Zou, Qingsong Yin, Lijuan Chen, Yongxian HU, Yong Xu, Qian Cheng, Yuelu Guo, Yujun Dong, Li Gao, Aining Xu, Songbai Cai, Wen Wang, Ming Wu, Jue Wang, Liting Chen, Jianfeng Zhou, Lugui Qiu
Journal: Blood
Blood (2021) 138 (Supplement 1): 547.
https://doi.org/10.1182/blood-2021-152576
Published: 2021
Journal Articles

A phase 1 study of a novel fully human BCMA-targeting CAR (CT103A) in patients with relapsed/refractory multiple myeloma

Clinical Trials & Observations
Di Wang, Jue Wang, Guang Hu, Wen Wang, Yi Xiao, Haodong Cai, Lijun Jiang, Li Meng, Yongkun Yang, Xiaoxi Zhou, Zhenya Hong, Zheng Yao, Min Xiao, Liting Chen, Xia Mao, Li Zhu, Jin Wang, Lugui Qiu, Chunrui Li, Jianfeng Zhou
Journal: Blood
Blood (2021) 137 (21): 2890–2901.
https://doi.org/10.1182/blood.2020008936
Published: 2021
Includes: Supplemental data
Journal Articles

CD19/CD22 CAR-T Cell Cocktail Therapy Following Autologous Transplantation in Patients with Relapsed/Refractory B-Cell Lymphomas

Yang Cao, Yi Xiao, Na Wang, MD PhD, Gaoxiang Wang, MDPhD, Xiaoxi Zhou, MDPhD, Liang Huang, MD, Liting Chen, PhD, Min Xiao, MD PhD, Tongcun Zhang, PhD, Yicheng Zhang, Jianfeng Zhou, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11.
https://doi.org/10.1182/blood-2020-140308
Published: 2020
Journal Articles

Efficacy and safety of CAR19/22 T-cell cocktail therapy in patients with refractory/relapsed B-cell malignancies

Clinical Trials & Observations
Na Wang, Xuelian Hu, Wenyue Cao, Chunrui Li, Yi Xiao, Yang Cao, Chaojiang Gu, Shangkun Zhang, Liting Chen, Jiali Cheng, Gaoxiang Wang, Xiaoxi Zhou, Miao Zheng, Xia Mao, Lijun Jiang, Di Wang, Qiuxiang Wang, Yaoyao Lou, Haodong Cai, Dandan Yan, Yicheng Zhang, Tongcun Zhang, Jianfeng Zhou, Liang Huang
Journal: Blood
Blood (2020) 135 (1): 17–27.
https://doi.org/10.1182/blood.2019000017
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Fully Human Bcma Targeting CAR T Cell Therapy in Relapsed/Refractory Multiple Myeloma

Chunrui Li, MD PhD, Jue Wang, MD PhD, Di Wang, MD PhD, Guang Hu, Yongkun Yang, Xiaoxi Zhou, MD PhD, Li Meng, MD PhD, Zhenya Hong, MD PhD, Liting Chen, PhD, Xia Mao, MD PhD, Min Xiao, MD PhD, Jianfeng Zhou, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 929.
https://doi.org/10.1182/blood-2019-128468
Published: 2019
Journal Articles

Autonomous Ca 2+ Oscillations Reflect Oncogenic Signaling in B-ALL Cells

Kohei Kume, PhD, Liting Chen, PhD, Jaewoong Lee, PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1253.
https://doi.org/10.1182/blood-2019-130708
Published: 2019
Journal Articles

Dynamic Assembly of a Feedback Complex to Regulate Oncogenic B-Cell Receptor-Signaling

Jaewoong Lee, PhD, Kohei Kume, PhD, Zhengshan Chen, MD PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Liting Chen, PhD, Lai N Chan, PhD, Lars Klemm, MS, Chun-Wei David Chen, PhD, Ning Ma, PhD, Wing C. Chan, MD, Stephen J Forman, MD, Francesca Zammarchi, PhD, Patrick Van Berkel, PhD, Ari Melnick, MD, Vu N Ngo, PhD, Huimin Geng, PhD, Selina M. Luger, MD FRCPC, Mark Litzow, MD, Michael T McManus, PhD, Nagarajan Vaidehi, PhD, Elisabeth M. Paietta, PhD, Eric Meffre, PhD, David M. Weinstock, MD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 393.
https://doi.org/10.1182/blood-2019-131270
Published: 2019
Journal Articles

Droplet Digital PCR Monitoring of TP53 Mutated Circulating Tumor DNA Levels in Lymphoma Patients

Xiaolu Long, Jia Gu, Yaoyao Lou, Qian Xu, Haodong Cai, MD, Wei Zhang, MD, Kefeng Shen, Min Xiao, MD PhD, Yicheng Zhang, MD PhD, Liting Chen, PhD, Jianfeng Zhou, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4106.
https://doi.org/10.1182/blood-2018-99-113825
Published: 2018
Journal Articles

Autonomous Ca 2+ Oscillations Reflect Oncogenic BCR-Signaling in Multiple B-Cell Malignancies and Are Essential for Survival and Proliferation

Kohei Kume, PhD, Liting Chen, PhD, Jae-Woong Lee, PhD, Markus Muschen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1373.
https://doi.org/10.1182/blood-2018-99-117315
Published: 2018
Journal Articles

Ca 2+ Oscillations and NFATC1 -Activation Enable Oncogenic Signaling in Pre-B Cell Transformation and Leukemogenesis

Kohei Kume, PhD, Liting Chen, PhD, Jaewoong Lee, PhD, Markus Muschen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2500.
https://doi.org/10.1182/blood.V130.Suppl_1.2500.2500
Published: 2017