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Journal Articles

Characterization of Allogeneic T Cells Expressing Inducible Caspase-9 Following Adoptive Transfer in Children Receiving an HLA-Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Myeloid Malignancies

Joanne Shaw, PhD, Xiaoou Zhou, MD PhD, An Lu, Valentina Bertaina, Daria Pagliara, MD PhD, Melissa Aldinger, PharmD, David M. Spencer, PhD, Franco Locatelli, Aaron Foster, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4534.
https://doi.org/10.1182/blood-2018-99-119779
Published: 2018
Journal Articles

Differential Expression of Inducible Caspase-9 (iC9) in Allogeneic T Cells Allows Selective Depletion of Activated T Cells Following Exposure to Rimiducid and Permits In Vivo Allodepletion

Xiaoou Zhou, MD PhD, An Lu, Kelly L Sharp, Margie Harris, Madhavi Anumula, MS, J. Bayle, PhD, David M. Spencer, PhD, Aaron Foster, PhD, Joanne Shaw, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3496.
https://doi.org/10.1182/blood-2018-99-119285
Published: 2018
Journal Articles

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

Clinical Trials & Observations
Xiaoou Zhou, Gianpietro Dotti, Robert A. Krance, Caridad A. Martinez, Swati Naik, Rammurti T. Kamble, April G. Durett, Olga Dakhova, Barbara Savoldo, Antonio Di Stasi, David M. Spencer, Yu-Feng Lin, Hao Liu, Bambi J. Grilley, Adrian P. Gee, Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner
Journal: Blood
Blood (2015) 125 (26): 4103–4113.
https://doi.org/10.1182/blood-2015-02-628354
Published: 2015
Includes: Supplemental data
Journal Articles

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

Clinical Trials & Observations
Xiaoou Zhou, Antonio Di Stasi, Siok-Keen Tey, Robert A. Krance, Caridad Martinez, Kathryn S. Leung, April G. Durett, Meng-Fen Wu, Hao Liu, Ann M. Leen, Barbara Savoldo, Yu-Feng Lin, Bambi J. Grilley, Adrian P. Gee, David M. Spencer, Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner, Gianpietro Dotti
Journal: Blood
Blood (2014) 123 (25): 3895–3905.
https://doi.org/10.1182/blood-2014-01-551671
Published: 2014
Includes: Supplemental data