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Wolfgang Huber, PhD
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Journal Articles

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

Sophie A. Herbst, MSc, Mattias Vesterlund, Rozbeh Jafari, PhD, Ioannis Siavelis, Matthias Stahl, Eva Schitter, Alexander J. Helmboldt, Murat Iskar, Nora Liebers, MD, Felix Czernilofsky, Tobias Roider, MD, Peter-Martin Bruch, Junyan Lu, Sarah Richter, Georgios Mermelekas, Husen Muhammad Umer, Mareike Knoll, Carolin Kolb, Angela Lenze, Xiaofang Cao, Cecilia Österholm-Corbascio, Sebastian Scheinost, Matthias Ganzinger, Larry Mansouri, PhD, Katharina Kriegsmann, MD, Mark Kriegsmann, MD, Carsten Mueller-Tidow, MD, Peter Dreger, MD, Simon Anders, PhD, Marc Zapatka, Marco Herling, MD, Richard Rosenquist, MD, Stephan Stilgenbauer, MD, Thorsten Zenz, Wolfgang Huber, PhD, Eugen Tausch, MD, Janne Lehtiö, Sascha Dietrich, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137528
Published: 2020
Journal Articles

The U1 Spliceosomal RNA: A Novel Non-Coding Hotspot Driver Mutation Independently Associated with Clinical Outcome in Chronic Lymphocytic Leukemia

Ferran Nadeu, Shimin Shuai, Ander Diaz-Navarro, Irene López, Silvia Martín, Hiromichi Suzuki, Romina Royo, Guillem Clot, Julio Delgado, Tycho Baumann, Junyan Lu, PhD, Alba Navarro, Marta Kulis, Sachin A Kumar, Ana Gutierrez-Fernandez, Miguel Alcoceba, Marcos González, Enrique Colado, Angel Ramirez Payer, Cristina Capdevila, Miguel Osuna, Marta Aymerich, Rosó Mares, Monica Lopez-Guerra, Laura Magnano, Pablo Mozas, Alfredo Rivas-Delgado, Maria Jose Terol, Anna Enjuanes, Wolfgang Huber, PhD, Armando Lopez-Guillermo, Sílvia Beà, José I. Martin-Subero, Thorsten Zenz, MD, Michael D Taylor, Dolors Colomer, PhD, Xose S Puente, Lincoln D Stein, Elias Campo
Journal: Blood
Blood (2019) 134 (Supplement_1): 847.
https://doi.org/10.1182/blood-2019-130052
Published: 2019
Journal Articles

Transcriptional Profiling Reveals Strong Impact of Major Molecular Disease Subgroups and Mixed Epistasis in Chronic Lymphocytic Leukemia

Thorsten Zenz, MD, Almut Luetge, Junyan Lu, PhD, Huellein Jennifer, PhD, Sascha Dietrich, MD, Leopold Sellner, MD, Wolfgang Huber, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1742.
https://doi.org/10.1182/blood-2019-126388
Published: 2019
Journal Articles

Ex-Vivo Drug Response Profiling for Tailoring Treatment in Hematologic Malignancies: The Prospective Non-Interventional SMART-Trial

Nora Liebers, Peter-Martin Bruch, Agnes Gambietz, Holly Giles, BA, Junyan Lu, PhD, Mareike Knoll, Carolin Kolb, Peter Dreger, Carsten Mueller-Tidow, MD, Wolfgang Huber, PhD, Axel Benner, Thorsten Zenz, MD, Sascha Dietrich, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 376.
https://doi.org/10.1182/blood-2019-125324
Published: 2019
Journal Articles

Systematic Investigation of Microenvironmental Drug Resistance Mechanisms in Chronic Lymphocytic Leukemia

Peter-Martin Bruch, Holly Giles, BA, Carolin Kolb, Sophie Rabe, MSc, Tobias Roider, MD, Mareike Knoll, Mark Kriegsmann, MD, Katharina Kriegsmann, MD, Christiane Zgorzelski, Sebastian Scheinost, Lena Wagner, Carsten Müller-Tidow, MD, Thorsten Zenz, MD, Wolfgang Huber, PhD, Sascha Dietrich, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3363.
https://doi.org/10.1182/blood-2019-128392
Published: 2019
Journal Articles

Asymptomatic Multiple Myeloma - Background of Progression, Evolution, and Prognosis

Anja Seckinger, MD, Anna Jauch, PhD, Martina Emde, Susanne Beck, Marcel Mohr, Martin Granzow, PhD, Thomas Hielscher, Thierry Rème, MD, Reinhard Schnettler, Nassim Fard, Katrin Hinderhofer, Paul Theodor Pyl, Wolfgang Huber, PhD, Vladimir Benes, PhD, Anna Marciniak-Czochra, Véronique Pantesco, Anthony D. Ho, MD, Bernard Klein, Jens Hillengass, MD, Dirk Hose, MD
Journal: Blood
Blood (2016) 128 (22): 235.
https://doi.org/10.1182/blood.V128.22.235.235
Published: 2016
Journal Articles

Subgroups of T-Cell Prolymphocytic Leukemia (T-PLL) Discovered By High-Throughput Ex Vivo Drug Testing and Genetic Profiling

Emma I Andersson, MSc, Shady Adnan, MD MSc, Leopold Sellner, MD, Dorine Bellanger, Alexandra Schrader, Giuliano Crispatzu, Henan Zhang, MD, Carlos C Mateos, PhD, Edgar Faber, MD PhD, Steffen Koschmieder, MD, Tim H. Brummendorf, MD PhD, Krister Wennerberg, PhD, Wei Ding, MD PhD, Marc-Henri Stern, MD PhD, Marco Herling, MD, Simon Anders, PhD, Wolfgang Huber, PhD, Thorsten Zenz, MD, Satu Mustjoki, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 315.
https://doi.org/10.1182/blood.V126.23.315.315
Published: 2015
Journal Articles

Discovery of Novel Drug Sensitivities in T-Prolymphocytic Leukemia (T-PLL) By High-Throughput Ex Vivo Drug Testing and Genetic Profiling

Emma I Andersson, MSc, Leopold Sellner, MD, Malgorzata Oles, Tea Pemovska, MSc, Paavo Pietarinen, MSc, Anneli Lauhio, MD, Katarzyna Tomska, Carlos Cuesta-Mateos, MD PhD, Edgar Faber, Tim H. Brummendorf, MD PhD, Olli Kallioniemi, MD PhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD, Wolfgang Huber, PhD, Krister Wennerberg, PhD, Thorsten Zenz, MD, Satu Mustjoki, MDPhD
Journal: Blood
Blood (2014) 124 (21): 917.
https://doi.org/10.1182/blood.V124.21.917.917
Published: 2014
Journal Articles

Systematic Mapping Of Drug and Pathway Sensitivity In Chronic Lymphocytic Leukemia Identifies Synthetic Lethal Interactions Of Mutant p53

Leopold Sellner, MD, Oles Malgorzata, Mikolaj Slabicki, PhD, Carolin Blume, Hüllein Jennifer, Tatjana Stolz, Martin Sill, PhD, Sascha Dietrich, MD, Olaf Merkel, PhD, Anna Jauch, PhD, Manfred Hensel, MD, Davide Rossi, Zirlik Katja, MD, Martina Seiffert, PhD, Anthony D. Ho, MD, von Kalle Christof, MD, Hanno Glimm, MD, Wolfgang Huber, PhD, Thorsten Zenz, MD
Journal: Blood
Blood (2013) 122 (21): 173.
https://doi.org/10.1182/blood.V122.21.173.173
Published: 2013