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Journal Articles

Early Safety and Feasibility Results from a Phase II Trial of De-Escalated Ptcy and Ruxolitinib for Gvhd Prophylaxis in Older Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

Sameem Abedin, Fateeha Furqan, Lyndsey Runaas, Walter Longo, Nirav N. Shah, Timothy S. Fenske, Marcelo C. Pasquini, William R Drobyski, Xue-Zhong Yu, Mehdi Hamadani

Blood (2024) 144 (Supplement 1): 1039.

https://doi.org/10.1182/blood-2024-200832

Published: 2024

Journal Articles

An Interleukin 27 Dependent Lysosomal Thiol Reductase Regulates Regulatory T Cell Survival and Mitochondrial Fitness during Graft Versus Host Disease

Jonathan Florentin, Alison Moe, Ravi K Shah, Jacek Zielonka, Mark Castleberry, Alex Myers, Marlenny Vargas-Cortes, Jessica L Schmeling, Anthony E Zamora, William R Drobyski

Blood (2024) 144 (Supplement 1): 261.

https://doi.org/10.1182/blood-2024-198173

Published: 2024

Journal Articles

Retinoic Acid Regulates Donor Myeloid Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation in Mice

Xinlei Li, Jianwei Zheng, Dian Zhou, Rachel Limpert, Brian Taylor, Linlu Tian, Xue-Zhong Yu, William R. Drobyski, Xiao Chen

Blood (2022) 140 (Supplement 1): 4482.

https://doi.org/10.1182/blood-2022-162723

Published: 2022

Journal Articles

Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease

Cheng Yin Yuan, Vivian Zhou, Garrett Sauber, Todd Stollenwerk, Richard Komorowski, Alicia López, Rosa María Tolón, Julian Romero, Cecilia J. Hillard, William R. Drobyski

Blood (2021) 137 (9): 1241–1255.

https://doi.org/10.1182/blood.2020004871

Published: 2021

Includes: Supplemental data

Journal Articles

Pathogenic Bhlhe40 + GM-CSF + CD4 + T cells promote indirect alloantigen presentation in the GI tract during GVHD

Clint Piper, Vivian Zhou, Richard Komorowski, Aniko Szabo, Benjamin Vincent, Jonathan Serody, Maria-Luisa Alegre, Brian T. Edelson, Reshma Taneja, William R. Drobyski

Blood (2020) 135 (8): 568–581.

https://doi.org/10.1182/blood.2019001696

Published: 2020

Includes: Supplemental data

Journal Articles

Recipient Signaling through the Cannabinoid Type 2 Receptor Regulates IL-6 Independent Neuroinflammation during Graft Versus Host Disease

Alison Moe, PhD, Garrett Sauber, BS, Vivian Zhou, PhD, Anissa Lapitz, BS, Cecilia Hillard, PhD, William R. Drobyski, MD

Blood (2019) 134 (Supplement_1): 195.

https://doi.org/10.1182/blood-2019-122746

Published: 2019

Journal Articles

Single Cell Immune Profiling of Colitogenic T Cells during Acute Graft Versus Host Disease Reveals Two Novel Transcriptionally Distinct CD4+ GM-CSF+ Lineages

Clinton Piper, BS, Achia Khatun, BS, Yao Chen, BS, Ryan Zander, PhD, Weiguo Cui, MD PhD, William R. Drobyski, MD

Blood (2019) 134 (Supplement_1): 197.

https://doi.org/10.1182/blood-2019-127095

Published: 2019

Journal Articles

A Bhlhe40/GM-CSF Axis Potentiates Gastrointestinal Tract Inflammation during Acute Graft Versus Host Disease

Clint Piper, BS, Vivan Zhou, PhD, Brian T. Edelson, MD PhD, Reshma Taneja, William R. Drobyski, MD

Blood (2018) 132 (Supplement 1): 62.

https://doi.org/10.1182/blood-2018-99-110807

Published: 2018

Journal Articles

Bim regulates the survival and suppressive capability of CD8 + FOXP3 + regulatory T cells during murine GVHD

Kimberle Agle, Benjamin G. Vincent, Clint Piper, Ludovic Belle, Vivian Zhou, Warren Shlomchik, Jonathan S. Serody, William R. Drobyski

Blood (2018) 132 (4): 435–447.

https://doi.org/10.1182/blood-2017-09-807156

Published: 2018

Includes: Supplemental data

Journal Articles

Bim Regulates the Survival and Suppressive Capability of CD8+ Foxp3+ Regulatory T Cells during Graft Versus Host Disease

Benjamin G. Vincent, MD, Kimberle A. Agle, PhD, Ludovic Belle, PhD, Vivan Zhou, PhD, Clint Piper, BS, Warren D Shlomchik, MD, Jonathan S Serody, MD, William R. Drobyski, MD

Blood (2017) 130 (Supplement 1): 209.

https://doi.org/10.1182/blood.V130.Suppl_1.209.209

Published: 2017

Journal Articles

Ixazomib for Chronic Graft-Versus-Host Disease (cGVHD) Prophylaxis in Patients Undergoing Allogeneic Transplantation (alloHCT): Preliminary Results of a Phase I/II Study

Saurabh Chhabra, MD, Parameswaran Hari, MD MRCP, MS, Alexis Visotcky, Nirav N Shah, MD, J. Douglas Rizzo, MD, Wael Saber, MD MS, Anita D'Souza, MBBS, Binod Dhakal, MBBS, Ashish Anshu, MS, PhD, Robert Thompson, Timothy S. Fenske, MD, Bronwen E. Shaw, PhD MRCP, FRCPath, William R. Drobyski, MD, Marcelo C. Pasquini, MD, Mehdi Hamadani, MD

Blood (2017) 130 (Supplement 1): 1974.

https://doi.org/10.1182/blood.V130.Suppl_1.1974.1974

Published: 2017

Journal Articles

Impact of Obesity on Outcomes of Elderly Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Myeloid Malignancies

Ensi Voshtina, DO, Aniko Szabo, PhD, Mehdi Hamadani, MD, Tim S. Fenske, MD, Anita D'Souza, MBBS, MD, Wael Saber, MD MS, William R. Drobyski, MD, Parameswaran Hari, MBBS, MD MRCP, Nirav N. Shah, MD MSHP

Blood (2016) 128 (22): 4667.

https://doi.org/10.1182/blood.V128.22.4667.4667

Published: 2016

Journal Articles

Host Interleukin 6 and Indoleamine 2,3 Dioxygenase Regulate Inflammation in the Brain during Graft Versus Host Disease

Ludovic Belle, PhD, Erin Koester, MS, Emily Hansen, PhD, Michael Lawlor, PhD, Cecilia Hillard, PhD, William R. Drobyski, MD

Blood (2016) 128 (22): 2145.

https://doi.org/10.1182/blood.V128.22.2145.2145

Published: 2016

Journal Articles

Tocilizumab Is Highly Active for Severe Steroid-Refractory Acute Graft-Versus-Host Disease of the Gastrointestinal Tract

Alex Ganetsky, PharmD, BCOP, Noelle V Frey, MD, Alison W Loren, MD MS, Elizabeth O. Hexner, MD, James K Mangan, MD PhD, Saar I Gill, MBBS, PhD, Selina Luger, MD, Adam D. Cohen, MD, Daria V Babushok, MDPhD, Edward A Stadtmauer, MD, Jacqueline Smith, CRNP, William R. Drobyski, MD, Sarah K Kraus, PharmD, Colleen Timlin, PharmD, BCOP, David L. Porter, MD

Blood (2016) 128 (22): 2245.

https://doi.org/10.1182/blood.V128.22.2245.2245

Published: 2016

Journal Articles

Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression

Ludovic Belle, Kimberle Agle, Vivian Zhou, Cheng Yin-Yuan, Richard Komorowski, Daniel Eastwood, Brent Logan, Jie Sun, Nico Ghilardi, Daniel Cua, Calvin B. Williams, Melanie Gaignage, Reece Marillier, Jacques van Snick, William R. Drobyski

Blood (2016) 128 (16): 2068–2082.

https://doi.org/10.1182/blood-2016-02-698241

Published: 2016

Journal Articles

Blockade of Interleukin 27 Signaling Attenuates Graft Versus Host Disease By Augmenting CD4 + and CD8 + Regulatory T Cell Reconstitution

Ludovic Belle, PhD, Kimberle A. Agle, PhD, Vivian Zhou, PhD, Vanessa Yuan, MS, Jie Sun, PhD, Nico Ghilardi, PhD, Jacques van Snick, PhD, William R. Drobyski, MD

Blood (2015) 126 (23): 150.

https://doi.org/10.1182/blood.V126.23.150.150

Published: 2015

Journal Articles

Coordinate Expression of Beta 2 Integrins and the Interleukin 23 Receptor Define a Pathogenic CD4+ T Cell Population That Induces Colonic Inflammation during Graft Versus Host Disease

Kimberle Agle, PhD, Vivian Zhou, PhD, Xiao Chen, MD PhD, Amy Beres, PhD, Richard Komorowski, MD, Carolyn Taylor, PhD, Dipica Haribhai, Calvin Williams, MD PhD, James Verbsky, MDPhD, Wendy Blumenschein, PhD, Svetlana Sadekova, PhD, Eddie Bowman, PhD, Casey Weaver, MD, Daniel Cua, PhD, William R. Drobyski, MD

Blood (2014) 124 (21): 537.

https://doi.org/10.1182/blood.V124.21.537.537

Published: 2014

Journal Articles

A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease

Xiao Chen, Joseph Dodge, Richard Komorowski, William R. Drobyski

Blood (2013) 121 (19): 3970–3980.

https://doi.org/10.1182/blood-2012-08-445130

Published: 2013

Journal Articles

A Critical Role for the Retinoic Acid Signaling Pathway in the Pathophysiology of Gastrointestinal Graft-Versus-Host Disease

Xiao Chen, MD, PhD, Joseph Dodge, William R. Drobyski, MD

Blood (2012) 120 (21): 341.

https://doi.org/10.1182/blood.V120.21.341.341

Published: 2012

Journal Articles

Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease

Hemalatha Rangarajan, Maryam Yassai, Hariharan Subramanian, Richard Komorowski, Megan Whitaker, Jack Gorski, William R. Drobyski

Blood (2012) 119 (26): 6354–6364.

https://doi.org/10.1182/blood-2012-01-401596

Published: 2012

Includes: Supplemental data

NARROW

Early Safety and Feasibility Results from a Phase II Trial of De-Escalated Ptcy and Ruxolitinib for Gvhd Prophylaxis in Older Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

An Interleukin 27 Dependent Lysosomal Thiol Reductase Regulates Regulatory T Cell Survival and Mitochondrial Fitness during Graft Versus Host Disease

Retinoic Acid Regulates Donor Myeloid Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation in Mice

Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease

Pathogenic Bhlhe40 + GM-CSF + CD4 + T cells promote indirect alloantigen presentation in the GI tract during GVHD

Recipient Signaling through the Cannabinoid Type 2 Receptor Regulates IL-6 Independent Neuroinflammation during Graft Versus Host Disease

Single Cell Immune Profiling of Colitogenic T Cells during Acute Graft Versus Host Disease Reveals Two Novel Transcriptionally Distinct CD4+ GM-CSF+ Lineages

A Bhlhe40/GM-CSF Axis Potentiates Gastrointestinal Tract Inflammation during Acute Graft Versus Host Disease

Bim regulates the survival and suppressive capability of CD8 + FOXP3 + regulatory T cells during murine GVHD

Bim Regulates the Survival and Suppressive Capability of CD8+ Foxp3+ Regulatory T Cells during Graft Versus Host Disease

Ixazomib for Chronic Graft-Versus-Host Disease (cGVHD) Prophylaxis in Patients Undergoing Allogeneic Transplantation (alloHCT): Preliminary Results of a Phase I/II Study

Impact of Obesity on Outcomes of Elderly Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Myeloid Malignancies

Host Interleukin 6 and Indoleamine 2,3 Dioxygenase Regulate Inflammation in the Brain during Graft Versus Host Disease

Tocilizumab Is Highly Active for Severe Steroid-Refractory Acute Graft-Versus-Host Disease of the Gastrointestinal Tract

Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression

Blockade of Interleukin 27 Signaling Attenuates Graft Versus Host Disease By Augmenting CD4 + and CD8 + Regulatory T Cell Reconstitution

Coordinate Expression of Beta 2 Integrins and the Interleukin 23 Receptor Define a Pathogenic CD4+ T Cell Population That Induces Colonic Inflammation during Graft Versus Host Disease

A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease

A Critical Role for the Retinoic Acid Signaling Pathway in the Pathophysiology of Gastrointestinal Graft-Versus-Host Disease

Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease

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American Society of Hematology

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American Society of Hematology

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