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Journal Articles

Unfractionated Heparin Resourced from Bovine, Ovine, and Porcine Origin Is Bioequivalent

Nikunj Thakkar, Kannan Meganathan, Yash Gupta, Gia Kapur, Jeanine M. Walenga, Debra Hoppensteadt, Walter Jeske, Pradeep Aggarwal, Jawed Fareed

Blood (2024) 144 (Supplement 1): 5577.

https://doi.org/10.1182/blood-2024-211016

Published: 2024

Journal Articles

The Inter-Relationship between Thrombo-Inflammatory Biomarkers and Cellular Indices of Inflammation in Early-Stage Lung Cancer Patients

Mark Jaradeh, Brett Curran, Kostantinos Poulikidis, Adrian Rodrigues, Walter Jeske, James Lubawski, Jeanine Walenga, Jawed Fareed, Zaid M. Abdelsattar, Wickii T. Vigneswaran

Blood (2022) 140 (Supplement 1): 11400–11401.

https://doi.org/10.1182/blood-2022-171085

Published: 2022

Journal Articles

USP Standardized Mixtures of Bovine, Ovine and Porcine Heparin Exhibit Comparable Biologic Effects to Referenced Single Sourced Heparins and May be Interchangeable,

Guy Olson, Walter Jeske, Omer Iqbal, Ambar Farooqui, Fakiha Siddiqui, Debra Hoppensteadt, Ahmed Kouta, Jawed Fareed, Eduardo Ramacciotti

Blood (2021) 138 (Supplement 1): 1067.

https://doi.org/10.1182/blood-2021-147995

Published: 2021

Journal Articles

Validation of the Bioequivalence of USP Potency Adjusted Porcine, Ovine, and Bovine Heparins

Nausheen Baig, Ahmed Kouta, Walter Jeske, PhD, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Omer Iqbal, MD, Fakiha Siddiqui, Mamdouh Bakhos, MD, Jawed Fareed, PhD

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-142861

Published: 2020

Journal Articles

Assay Dependent Reversal of the Oral and Parenteral Anti-Xa Agents By Andexanet Alfa

Fakiha Siddiqui, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Walter Jeske, PhD, Alfonso J Tafur, MD MS, Eduardo Ramacciotti, PhD MD, Jawed Fareed, PhD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142653

Published: 2020

Journal Articles

Potency Equated Porcine and Bovine Mucosal Heparin Are Bioequivalent in Terms of Biochemical and Pharmacological Effects

Nausheen Baig, Ahmed Kouta, Fakiha Siddiqui, Ambar Farooqui, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Cassie Bacher, Sharan Krishnappan, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 3665.

https://doi.org/10.1182/blood-2019-126075

Published: 2019

Journal Articles

Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma

Debra Hoppensteadt, PhD, Emily Bontekoe, Fakiha Siddiqui, Ambar Farooqui, Omer Iqbal, MD, Walter Jeske, PhD, Jeanine Walenga, PhD, Alfonso J Tafur, MD MS, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 3374.

https://doi.org/10.1182/blood-2019-131221

Published: 2019

Journal Articles

Bovine Heparin Demonstrates the Same Interaction with HIT Antibodies As Porcine Heparin

Jeanine Walenga, PhD, Walter Jeske, PhD, Sabrina Bertini, Giulia Risi, Michelle Sung, BS, Ambar Farooqui, Cassie Bacher, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Bruce Lewis, Mamdouh Bakhos, MD

Blood (2019) 134 (Supplement_1): 2351.

https://doi.org/10.1182/blood-2019-127304

Published: 2019

Journal Articles

Comparative Studies on the Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies

Ambar Farooqui, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Cassie Bacher, Jeanine Walenga, PhD, Ahmed Kouta, Walter Jeske, PhD, Bruce Lewis, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 2446.

https://doi.org/10.1182/blood-2019-131825

Published: 2019

Journal Articles

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Ahmed Kouta, Walter Jeske, PhD, Rick Duff, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 165.

https://doi.org/10.1182/blood-2019-131943

Published: 2019

Journal Articles

Andexanet Alpha Differentially Neutralizes the Anticoagulant, Antiprotease and Thrombin Generation Inhibitory Effects of Unfractionated Heparin, Enoxaparin and Fondaparinux

Fakiha Siddiqui, Alfonso J Tafur, MD MS, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Walter Jeske, PhD, Emily Bontekoe, Ahmed Kouta, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 1158.

https://doi.org/10.1182/blood-2019-127072

Published: 2019

Journal Articles

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban By Andexanet Alfa As Measured By Whole Blood Thromboelastographic Analysis

Siddharth Mehrotra, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Alfonso J Tafur, MD MS, Bruce Lewis, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 1155.

https://doi.org/10.1182/blood-2019-131907

Published: 2019

Journal Articles

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

Fakiha Siddiqui, Siddharth Mehrotra, Vishnu Venkitasubramony, Rithik Raina, Lorenzo Storino Ramacciotti, Jack Bontekoe, BS, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 2520.

https://doi.org/10.1182/blood-2018-99-116993

Published: 2018

Journal Articles

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Michelle Sung, BS, Jeanine Walenga, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Mamdouh Bakhos, MD

Blood (2018) 132 (Supplement 1): 2540.

https://doi.org/10.1182/blood-2018-99-118781

Published: 2018

Journal Articles

Bovine Heparin Compared to Porcine Heparin to Demonstrate Bioequivalence

Marco Khiella, Walter Jeske, PhD, Jeanine Walenga, PhD, Omer Iqbal, MD, Rajan Laddu, Fakiha Siddiqui, Mamdouh Bakhos, MD

Blood (2018) 132 (Supplement 1): 1253.

https://doi.org/10.1182/blood-2018-99-118809

Published: 2018

Journal Articles

Differential Modulation of Plasminogen Activator Mediated Thrombolysis By Recombinant Thrombomodulin and Activated Protein C

Jawed Fareed, PhD, Zafar Siddiqui, Sanchayana Raghuvir, Sid Mehrota, Omer Iqbal, Walter Jeske, Debra Hoppensteadt, PhD, Kosuke Tanaka, Kazuhisa Tsuruta

Blood (2017) 130 (Supplement 1): 4865.

https://doi.org/10.1182/blood.V130.Suppl_1.4865.4865

Published: 2017

Journal Articles

Biochemical and Pharmacological Differentiation of APC and Recombinant Thrombomodulin with Reference to the Effect on the Hemostatic and Fibrinolytic Processes

Jawed Fareed, PhD, Debra Hoppensteadt, PhD, Walter Jeske, Omer Iqbal, Schuharazad Abro, Destini Clarizio, Sanchayana Raghuvir, Rachael Wasmund, Kosuke Tanaka, Kazuhisa Tsuruta

Blood (2017) 130 (Supplement 1): 4871.

https://doi.org/10.1182/blood.V130.Suppl_1.4871.4871

Published: 2017

Journal Articles

Inhibition of Thrombin and Its Generation By Recombinant Thrombomodulin and Activated Protein C in Whole Blood and Plasma Based Systems

Jawed Fareed, PhD, Debra Hoppensteadt, PhD, Walter Jeske, Jeanine Walenga, Paula D'Almeida Maia, BA, BS, Kosuke Tanaka, Kazuhisa Tsuruta

Blood (2017) 130 (Supplement 1): 4915.

https://doi.org/10.1182/blood.V130.Suppl_1.4915.4915

Published: 2017

Journal Articles

Use of a Synthetic Collagen to Monitor Platelet Function in Patients Receiving Dual Antiplatelet Therapy

Walter Jeske, Vicki Escalante, Wendy Klein, Carol Kartje, Jeanine Walenga, Mamdouh Bakhos

Blood (2017) 130 (Supplement 1): 4911.

https://doi.org/10.1182/blood.V130.Suppl_1.4911.4911

Published: 2017

Journal Articles

Zika and Chikungunya Virus and Risk for Venous Thromboembolism

Eduardo Ramacciotti, Leandro Agati, Valeria Aguiar, Thomas Wakefield, Anthony Comerota, MD, Jeanine Walenga, Walter Jeske, Jawed Fareed, PhD

Blood (2017) 130 (Supplement 1): 4883.

https://doi.org/10.1182/blood.V130.Suppl_1.4883.4883

Published: 2017

NARROW

Unfractionated Heparin Resourced from Bovine, Ovine, and Porcine Origin Is Bioequivalent

The Inter-Relationship between Thrombo-Inflammatory Biomarkers and Cellular Indices of Inflammation in Early-Stage Lung Cancer Patients

USP Standardized Mixtures of Bovine, Ovine and Porcine Heparin Exhibit Comparable Biologic Effects to Referenced Single Sourced Heparins and May be Interchangeable,

Validation of the Bioequivalence of USP Potency Adjusted Porcine, Ovine, and Bovine Heparins

Assay Dependent Reversal of the Oral and Parenteral Anti-Xa Agents By Andexanet Alfa

Potency Equated Porcine and Bovine Mucosal Heparin Are Bioequivalent in Terms of Biochemical and Pharmacological Effects

Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma

Bovine Heparin Demonstrates the Same Interaction with HIT Antibodies As Porcine Heparin

Comparative Studies on the Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Andexanet Alpha Differentially Neutralizes the Anticoagulant, Antiprotease and Thrombin Generation Inhibitory Effects of Unfractionated Heparin, Enoxaparin and Fondaparinux

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban By Andexanet Alfa As Measured By Whole Blood Thromboelastographic Analysis

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Bovine Heparin Compared to Porcine Heparin to Demonstrate Bioequivalence

Differential Modulation of Plasminogen Activator Mediated Thrombolysis By Recombinant Thrombomodulin and Activated Protein C

Biochemical and Pharmacological Differentiation of APC and Recombinant Thrombomodulin with Reference to the Effect on the Hemostatic and Fibrinolytic Processes

Inhibition of Thrombin and Its Generation By Recombinant Thrombomodulin and Activated Protein C in Whole Blood and Plasma Based Systems

Use of a Synthetic Collagen to Monitor Platelet Function in Patients Receiving Dual Antiplatelet Therapy

Zika and Chikungunya Virus and Risk for Venous Thromboembolism

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American Society of Hematology

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American Society of Hematology

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