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Journal Articles

Barriers to Successful Implementation of Precision Medicine to the Treatment of Refractory AML: Lessons Learned

Blood (2017) 130 (Supplement 1): 4622.

https://doi.org/10.1182/blood.V130.Suppl_1.4622.4622

Published: 2017

Journal Articles

Results from the U.S. Life after Stopping TKIs (LAST) Study

Blood (2017) 130 (Supplement 1): 2903.

https://doi.org/10.1182/blood.V130.Suppl_1.2903.2903

Published: 2017

Journal Articles

Rates of CR with and without Measurable Residual Disease after Induction Treatment with "7+3" or Azacitidine/Decitabine for Newly-Diagnosed AML

Todd Yezefski, MD, Roland B. Walter, MD PhD, Pamela S. Becker, MD PhD, Paul C. Hendrie, MD PhD, Vivian Oehler, MD, Mary-Elizabeth M. Percival, MD MS, Elihu H. Estey, MD

Blood (2016) 128 (22): 2792.

https://doi.org/10.1182/blood.V128.22.2792.2792

Published: 2016

Journal Articles

A Precision Medicine Approach Incorporating Both Molecular and In Vitro Functional Data to Treat Patients with Relapsed/Refractory Acute Myeloid Leukemia

Blood (2016) 128 (22): 4043.

https://doi.org/10.1182/blood.V128.22.4043.4043

Published: 2016

Journal Articles

Age-Related Changes in the Interaction of Acute Myeloid Leukemia with the Bone Marrow Microenvironment Correlate with Response to Treatment and Survival: A Role for L-Selectin

Joe C Huang, MD, Yifan Lu, B.S., Julia Sidorova, PhD, Sylvia Chien, Vivian Oehler, MD, Kenneth J Kopecky, PhD, Pamela S. Becker, MD PhD

Blood (2016) 128 (22): 5063.

https://doi.org/10.1182/blood.V128.22.5063.5063

Published: 2016

Journal Articles

MS4A3: A New Player in Leukemic Stem Cell Survival in Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Jamshid S. Khorashad, MD PhD, Anupriya Agarwal, PhD, Clinton C. Mason, PhD, Russell Bell, PhD, Anna Senina, MS, Anthony D. Pomicter, MS, Fan Yu, MD, Hannah M. Redwine, Amber D. Bowler, Phillip M. Clair, MS, Srinivas K. Tantravahi, MD, Shannon K. McWeeney, Brian J. Druker, MD, Derek L. Stirewalt, Vivian Oehler, MD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2016) 128 (22): 934.

https://doi.org/10.1182/blood.V128.22.934.934

Published: 2016

Journal Articles

Clinical Evaluation of Xpert® BCR-ABL Ultra, an Automated and Standardized Cartridge-Based Assay for the Quantification of BCR-ABL1

Michael J. Mauro, MD, Richard D. Press, MD PhD, David S. Snyder, MD, Qin Huang, MD PhD, Javier Pinilla-Ibarz, Dahui Qin, MD PhD, Christina Lockwood, PhD, Jacqueline E. Payton, MD PhD, Geoffrey L. Uy, MD, Matt E. Kalaycio, MD, Ramon V. Tiu, MD BS, Vivian Oehler, MD, Gwo-Jen Day, PhD, Wendy Wong, Michael P. Bates, MD, Jerald P. Radich

Blood (2015) 126 (23): 5170.

https://doi.org/10.1182/blood.V126.23.5170.5170

Published: 2015

Journal Articles

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

Emilia L. Lim, Diane L. Trinh, MSc, Rhonda E. Ries, MA, Yussanne Ma, PhD, James Topham, Maya D. Hughes, MD, Erin Pleasance, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, Yongjun Zhao, PhD, Daniela S. Gerhard, PhD, Vivian Oehler, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD PhD, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD

Blood (2015) 126 (23): 687.

https://doi.org/10.1182/blood.V126.23.687.687

Published: 2015

Journal Articles

Big Data Approach to Identify Molecular Basis for Drug Sensitivity Phenotypes in Acute Myeloid Leukemia

Su-In Lee, PhD, Benjamin Logsdon, PhD, Akanksha Saxena, BS, Vivian Oehler, MD, Chris P. Miller, PhD, C. Anthony Blau, MD, Pamela S. Becker, MD PhD

Blood (2014) 124 (21): 265.

https://doi.org/10.1182/blood.V124.21.265.265

Published: 2014

Journal Articles

Functional miRNA Expression Library Screen Identifies miRNAs That Alter Proliferation and Differentiation in Acute Myeloid Leukemia

Valerie A. Morris, PhD, Carrie Cummings, Soheil Meshinchi, MD PhD, Vivian Oehler, MD

Blood (2014) 124 (21): 3541.

https://doi.org/10.1182/blood.V124.21.3541.3541

Published: 2014

Journal Articles

BCR-ABL Testing Frequency Lower Than NCCN Recommendations in Lab Network Review of CML Patients

Carol Smyth, MB, Jason Bhan, MD, Tatiana Sorokina, MSc, Niyati Parikh, MSc, Vivian Oehler, MD, Jerald Radich, MD

Blood (2014) 124 (21): 1807.

https://doi.org/10.1182/blood.V124.21.1807.1807

Published: 2014

Journal Articles

Krüppel-like Factors KLF4 and KLF2 Regulate microRNA-150 Expression in Myeloid Leukemias

Valerie A. Morris, PhD, Carrie Cummings, Brendan Korb, Sean M. Boaglio, Vivian Oehler, MD

Blood (2014) 124 (21): 874.

https://doi.org/10.1182/blood.V124.21.874.874

Published: 2014

Journal Articles

Feasibility Trial of Individualized Therapy for Relapsed or Refractory Acute Myeloid Leukemia Based on a High Throughput in Vitro Drug Sensitivity Assay

Pamela S. Becker, MD PhD, Vivian Oehler, MD, Elihu H. Estey, MD, Timothy Martins, PhD, Andrea Perdue, PA-C, Jodie David, RN, Sylvia Chien, Paul C. Hendrie, MD PhD, Fabiana Ostronoff, MD, C. Anthony Blau, MD

Blood (2014) 124 (21): 3748.

https://doi.org/10.1182/blood.V124.21.3748.3748

Published: 2014

Journal Articles

Characterization of Mesenchymal Stromal Cells (MSCs) Derived From Acute Myeloid Leukemia (AML) Bone Marrow

Soumit K. Basu, MD, PhD, Xin Zhao, MD, Sylvia Chien, Min Fang, MD, PhD, Vivian Oehler, MD, Pamela S Becker, MD, PhD

Blood (2011) 118 (21): 2558.

https://doi.org/10.1182/blood.V118.21.2558.2558

Published: 2011

Journal Articles

PF-04449913 Reverts Multi Drug Resistance (MDR) by a Strong Down-Regulation of ABCA2 and BCL2 on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Blood (2011) 118 (21): 1429.

https://doi.org/10.1182/blood.V118.21.1429.1429

Published: 2011

Journal Articles

Phase 1 Dose-Escalation Study of PF-04449913, An Oral Hedgehog (Hh) Inhibitor, in Patients with Select Hematologic Malignancies

Catriona Jamieson, Jorge E. Cortes, Vivian Oehler, MD, Michele Baccarani, MD, Hagop M. Kantarjian, Cristina Papayannidis, Kristen N. Rice, MD, Xiaoxi Zhang, Naveed Shaik, Rachel Courtney, PhD, Wendy J. Levin, MD, MS, Giovanni Martinelli, MD

Blood (2011) 118 (21): 424.

https://doi.org/10.1182/blood.V118.21.424.424

Published: 2011

Journal Articles

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Blood (2011) 118 (21): 1535.

https://doi.org/10.1182/blood.V118.21.1535.1535

Published: 2011

Journal Articles

Prognostic Implications of the IDH1 synonymous SNP rs11554137 In Pediatric and Adult AML: a Children's Oncology Group and Southwest Oncology Group Study

Blood (2010) 116 (21): 2737.

https://doi.org/10.1182/blood.V116.21.2737.2737

Published: 2010

Journal Articles

Over-Expression of Novel IRF8 Splice Variants Is Associated with a Significant Decrease In Relapse-Free Survival In Adult AML Patients.

Era L. Pogosova-Agadjanyan, Kenneth J. Kopecky, PhD, Hana Lee, Jeanne E. Anderson, MD, John E. Godwin, MD, MS, Alan F. List, Soheil Meshinchi, MD, PhD, Vivian Oehler, MD, Stephen H. Petersdorf, MD, Cheryl L. Willman, MD, Frederick R. Appelbaum, MD, Jerald P. Radich, MD, Derek L. Stirewalt, MD

Blood (2010) 116 (21): 1679.

https://doi.org/10.1182/blood.V116.21.1679.1679

Published: 2010

Journal Articles

The Gamma Catenin/CBP Complex Maintains Survivin Transcription In β-Catenin Deficient/Depleted Cancer Cells.

Yong-Mi Kim, MD, MPH, PhD, Hong Ma, Ph.D., Vivian Oehler, MD, Enzi Jiang, MD, PhD, Cu Nguyen, David P. Masiello, MD, Han Liu, Yi Zhao, MD, PhD, Jerald P. Radich, MD, Michael Kahn

Blood (2010) 116 (21): 1218.

https://doi.org/10.1182/blood.V116.21.1218.1218

Published: 2010

NARROW

Barriers to Successful Implementation of Precision Medicine to the Treatment of Refractory AML: Lessons Learned

Results from the U.S. Life after Stopping TKIs (LAST) Study

Rates of CR with and without Measurable Residual Disease after Induction Treatment with "7+3" or Azacitidine/Decitabine for Newly-Diagnosed AML

A Precision Medicine Approach Incorporating Both Molecular and In Vitro Functional Data to Treat Patients with Relapsed/Refractory Acute Myeloid Leukemia

Age-Related Changes in the Interaction of Acute Myeloid Leukemia with the Bone Marrow Microenvironment Correlate with Response to Treatment and Survival: A Role for L-Selectin

MS4A3: A New Player in Leukemic Stem Cell Survival in Chronic Myeloid Leukemia

Clinical Evaluation of Xpert® BCR-ABL Ultra, an Automated and Standardized Cartridge-Based Assay for the Quantification of BCR-ABL1

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

Big Data Approach to Identify Molecular Basis for Drug Sensitivity Phenotypes in Acute Myeloid Leukemia

Functional miRNA Expression Library Screen Identifies miRNAs That Alter Proliferation and Differentiation in Acute Myeloid Leukemia

BCR-ABL Testing Frequency Lower Than NCCN Recommendations in Lab Network Review of CML Patients

Krüppel-like Factors KLF4 and KLF2 Regulate microRNA-150 Expression in Myeloid Leukemias

Feasibility Trial of Individualized Therapy for Relapsed or Refractory Acute Myeloid Leukemia Based on a High Throughput in Vitro Drug Sensitivity Assay

Characterization of Mesenchymal Stromal Cells (MSCs) Derived From Acute Myeloid Leukemia (AML) Bone Marrow

PF-04449913 Reverts Multi Drug Resistance (MDR) by a Strong Down-Regulation of ABCA2 and BCL2 on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Phase 1 Dose-Escalation Study of PF-04449913, An Oral Hedgehog (Hh) Inhibitor, in Patients with Select Hematologic Malignancies

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Prognostic Implications of the IDH1 synonymous SNP rs11554137 In Pediatric and Adult AML: a Children's Oncology Group and Southwest Oncology Group Study

Over-Expression of Novel IRF8 Splice Variants Is Associated with a Significant Decrease In Relapse-Free Survival In Adult AML Patients.

The Gamma Catenin/CBP Complex Maintains Survivin Transcription In β-Catenin Deficient/Depleted Cancer Cells.

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American Society of Hematology

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American Society of Hematology

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