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Tony Taldone, PhD
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Journal Articles

Harnessing the Epichaperome As a Therapeutic Approach in Multiple Myeloma

Eloisi Caldas Lopes, PhD, Tai Wang, PhD, David S Jayabalan, MSc, Tony Taldone, PhD, Jorge Monge, MD, Jorge Contreras, MD, Yip Winnie, Vicenta Trujillo, PhD, Panchal Palak, Nicholas Lombardi, Sharma Sahil, PhD, Digwal Chander, PhD, Morton Coleman, MD, Gabriela Chiosis, PhD, Ruben Niesvizky, MD, Monica L. Guzman, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4399.
https://doi.org/10.1182/blood-2019-125267
Published: 2019
Journal Articles

PTPN11 Mutated Acute Myeloid Leukemia (AML) Features an Abundant Epichaperome Network and Is Sensitive to the Epichaperome Inhibitor PU-H71

Justin D. Kaner, MD, Montreh Tavakkoli, MA,MD, Lisa Toudic, Brett M. Stevens, PhD, Craig T Jordan, PhD, Tony Taldone, PhD, Gabriela Chiosis, PhD, Ellen K. Ritchie, MD, Pinkal Desai, MDMPH, Michael B. Samuel, MD, Sangmin Lee, MD, Gail J. Roboz, MD, Monica L. Guzman, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3935.
https://doi.org/10.1182/blood-2019-128276
Published: 2019
Journal Articles

Epichaperome Abundance Predicts Response to the Epichaperome Inhibitor, Puh-71, in Acute Myeloid Leukemia

Montreh Tavakkoli, MA,MD, Justin D. Kaner, MD, Sharma Sahil, PhD, Tony Taldone, PhD, Swathi Merugu, PhD, Gabriela Chiosis, PhD, Gail J. Roboz, MD, Monica L. Guzman, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5145.
https://doi.org/10.1182/blood-2019-125175
Published: 2019
Journal Articles

HSP90 Facilitates Oncogene-Induced Metabolic Reprogramming in B-Cell Lymphomas

Maria Nieves Calvo Vidal, PhD, Jan Krumsiek, PhD, Jayeshkumar Patel, MS, Shao Ning Yang, Jude M Phillip, DPhil, Rossella Marullo, MD PhD, Tony Taldone, PhD, Giorgio Inghirami, MD, Ari Melnick, MD, Gabriela Chiosis, PhD, Leandro Cerchietti, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 645.
https://doi.org/10.1182/blood.V130.Suppl_1.645.645
Published: 2017
Journal Articles

Targeting the Hsp90 Oncoproteome in Burkitt Lymphoma

Lisa Giulino Roth, MD, Herman van Besien, Anna Rodina, PhD, Tony Taldone, PhD, Hediye Erdjument-Bromage, PhD, Matthew J. Barth, MD, Gabriela Chiosis, PhD, Ethel Cesarman
Journal: Blood
Blood (2015) 126 (23): 592.
https://doi.org/10.1182/blood.V126.23.592.592
Published: 2015
Journal Articles

A Hyperactive Signalosome Results in High Sensitivity to HSP90 Inhibitors in AML

Hongliang Zong, MD PhD, Tony Taldone, PhD, Gail J. Roboz, MD, Gabriela Chiosis, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2015) 126 (23): 2567.
https://doi.org/10.1182/blood.V126.23.2567.2567
Published: 2015
Journal Articles

Combination Therapy Using JAK2 and HSP90 Inhibitors Increased Efficacy in Myelofibrosis in Vivo

Ross L. Levine, Priya Koppikar, Sachie Marubayashi, Neha Bhagwat, Tony Taldone, PhD, Christopher Y. Park, MD, PhD, Gabriela Chiosis, PhD
Journal: Blood
Blood (2012) 120 (21): 805.
https://doi.org/10.1182/blood.V120.21.805.805
Published: 2012
Journal Articles

Anti-Apoptotic Bcl2 and Bcl-Xl Proteins Involved in Stroma-Induced Drug Tolerance to Hsp70 and Hsp90 Inhibitors in Leukemia and B-Cell Lymphoma

Eloisi Caldas Lopes, Fabian M Correa, Ling-Bo Shen, Jae-Hung Shieh, PhD, Tony Taldone, PhD, Gabriela Chiosis, PhD, Malcolm A.S. Moore, PhD
Journal: Blood
Blood (2012) 120 (21): 4900.
https://doi.org/10.1182/blood.V120.21.4900.4900
Published: 2012
Journal Articles

HSP70 Inhibitor, YK5, Ablates Blast, Progenitor and Stem Cell Populations in Primary Acute Myelogenous Leukemia Cells

Juan Felipe Rico, MD, Krishan K. Sharma, Yanlong Kang, PhD, Tony Taldone, PhD, Hardik Patel, Sarah Brennan, PhD, Hongliang Zong, MD, PhD, Michael W. Becker, MD, Gail J. Roboz, MD, Gabriela Chiosis, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2011) 118 (21): 2493.
https://doi.org/10.1182/blood.V118.21.2493.2493
Published: 2011
Journal Articles

FLT3-ITD+ AML Blast, Progenitor and Stem Cell Populations Demonstrate Higher Sensitivity to the Hsp90 Inhibitor PU-H71,

Hongliang Zong, MD, PhD, Tony Taldone, PhD, James H. Ahn, Sarah Brennan, PhD, Jeanne P. De Leon, Michael W. Becker, MD, Gail J. Roboz, MD, Gabriela Chiosis, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2011) 118 (21): 3500.
https://doi.org/10.1182/blood.V118.21.3500.3500
Published: 2011