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Tomoyuki Igawa
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Journal Articles

Pharmacology and Pharmacokinetics of NXT007; Emicizumab-Based Engineered Fixa/Fx Bispecific Antibody with Improved Properties

Kazuki Yamaguchi, Tetsuhiro Soeda, PhD, Motohiko Sato, Norihito Shibahara, PhD, Hikaru Koga, Mina Ichiki, Eri Joyashiki, Yuri Teranishi, Kei Nishimura, Hirotake Shiraiwa, Hidetomo Kitamura, PhD DVM, Tomoyuki Igawa, PhD, Hiroko Konishi, Takehisa Kitazawa, DVM
Journal: Blood
Blood (2020) 136 (Supplement 1): 19.
https://doi.org/10.1182/blood-2020-138958
Published: 2020
Journal Articles

SKY59: A Long-Lasting Engineered Anti-C5 Antibody for Subcutaneously Injectable Anti-Complement Therapy

Kenta Haraya, PhD, Zenjiro Sampei, PhD, Tatsuhiko Tachibana, PhD, Taku Fukuzawa, PhD, Siok Wan Gan, PhD, Meiri Shida-Kawazoe, PhD, Yuichiro Shimizu, PhD, Masaru Muraoka, PhD, Tomoyuki Igawa, PhD, Takehisa Kitazawa, DVM, Junichi Nezu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3611.
https://doi.org/10.1182/blood-2018-99-110145
Published: 2018
Journal Articles

Anti-factor IXa/X bispecific antibody ACE910 prevents joint bleeds in a long-term primate model of acquired hemophilia A

Atsushi Muto, Kazutaka Yoshihashi, Minako Takeda, Takehisa Kitazawa, Tetsuhiro Soeda, Tomoyuki Igawa, Zenjiro Sampei, Taichi Kuramochi, Akihisa Sakamoto, Kenta Haraya, Kenji Adachi, Yoshiki Kawabe, Keiji Nogami, Midori Shima, Kunihiro Hattori
Journal: Blood
Blood (2014) 124 (20): 3165–3171.
https://doi.org/10.1182/blood-2014-07-585737
Published: 2014
Includes: Supplemental data
Journal Articles

Hemostatic Effect of a Novel Bispecific Antibody (ACE910) Against Activated Factor IX and Factor X in an Acquired Hemophilia A Model

Atsushi Muto, Takehisa Kitazawa, DVM, Kazutaka Yoshihasi, DVM, PhD, Minako Takeda, DVM, Tetsuhiro Soeda, PhD, Tomoyuki Igawa, PhD, Zenjiro Sampei, Yuichiro Sakamoto, Yukiko Okuyama-Nishida, PhD, Hiroyuki Saito, Yoshiki Kawabe, PhD, Midori Shima, MD, PhD, Akira Yoshioka, MD, PhD, Kunihiro Hattori, PhD
Journal: Blood
Blood (2012) 120 (21): 42.
https://doi.org/10.1182/blood.V120.21.42.42
Published: 2012
Journal Articles

Generation of a Novel Bispecific Antibody (ACE910) Against Activated Factor IX and Factor X Mimicking the Function of Factor VIII Cofactor Activity

Tomoyuki Igawa, PhD, Zenjiro Sampei, Tetsuhiro Soeda, PhD, Yukiko Okuyama-Nishida, PhD, Chifumi Moriyama, Tetsuya Wakabayashi, Eriko Tanaka, Atsushi Muto, Tetsuo Kojima, PhD, Takehisa Kitazawa, DVM, Kazutaka Yoshihashi, DVM, PhD, Aya Harada, Miho Funaki, Kenta Haraya, Tachibana Tatsuhiko, PhD, Sachiyo Suzuki, Keiko Esaki, Yoshiaki Nabuchi, PhD, Kunihiro Hattori, PhD
Journal: Blood
Blood (2012) 120 (21): 1126.
https://doi.org/10.1182/blood.V120.21.1126.1126
Published: 2012
Journal Articles

Humanized Sc(Fv)2 Minibody against C-Mpl Successfully Increased Platelet Number in Monkey and Increased Engraftment of Human Umbilical Cord Blood Cells in NOD/SCID Mouse.

Takashi Yoshikubo, Yoshihiro Matsumoto, Masahiko Nanami, Takayuki Sakurai, Hiroyuki Tsunoda, Akihisa Kaneko, Yukiko Inagaki, Masashi Shiina, Mizuho Noguchi, Makoto Monnai, Souhei Ohyama, Yukihito Miura, Tetsuro Orita, Yasufumi Kikuchi, Tomoyuki Igawa, Kunihiro Hattori, Hisafumi Okabe
Journal: Blood
Blood (2008) 112 (11): 2322.
https://doi.org/10.1182/blood.V112.11.2322.2322
Published: 2008