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Journal Articles

Cytokine-Induced Memory-like (ML) NK Cells Persist for > 2 Months Following Adoptive Transfer into Leukemia Patients with a MHC-Compatible Hematopoietic Cell Transplant (HCT)

Jennifer A Foltz, PhD, Melissa M Berrien-Elliott, PhD, Carly Neal, B.S., Mark Foster, Ethan McClain, Tim Schappe, BS, Sweta Desai, Michelle Becker-Hapak, BS, Amanda F Cashen, MD, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 1954.

https://doi.org/10.1182/blood-2019-126004

Published: 2019

Journal Articles

Romidepsin in Combination with Gemcitabine, Oxaliplatin, and Dexamethasone Shows Durable Responses in Aggressive Lymphomas

Neha Mehta-Shah, MD, Peter A. Riedell, MD, Nancy L. Bartlett, MD, Amanda F Cashen, MD, Brad S. Kahl, MD, Todd A Fehniger, MD PhD, Chaz Moreno, Jingxia Liu, MS, PhD, Kenneth R. Carson, MD PhD

Blood (2019) 134 (Supplement_1): 1550.

https://doi.org/10.1182/blood-2019-124185

Published: 2019

Journal Articles

Potently Cytotoxic Natural Killer Cell Potential Initially Emerges from Erythro-Myeloid Progenitors during Mammalian Development

Carissa Dege, PhD, Katherine H Fegan, MS, J Philip Creamer, IV, BA,BS, Melissa M Berrien-Elliott, PhD, Stephanie A. Luff, PhD, Julia A Wagner, PhD, Paul D. Kingsley, PhD, Kathleen E. McGrath, PhD, Todd A Fehniger, MD PhD, James Palis, MD, Christopher M. Sturgeon, PhD

Blood (2019) 134 (Supplement_1): 2464.

https://doi.org/10.1182/blood-2019-130347

Published: 2019

Journal Articles

Chimeric Antigen Receptor Modified Memory-like (CAR-ML) NK Cells Exhibit Potent Responses to NK-Resistant Tumors

Melissa M Berrien-Elliott, PhD, Margery Gang, Nancy M Marin Agudelo, PhD, Lynne M Marsala, Mark Foster, Carly Neal, B.S., Wong Pamela, B.S., Wei M Meng, B.S., Maximilian M Schaettler, B.S., Tim Schappe, BS, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 869.

https://doi.org/10.1182/blood-2019-127546

Published: 2019

Journal Articles

System-Level Disease-Driven Immune Signatures in Patients with Diffuse Large B-Cell Lymphoma Associated with Poor Survival

Astrid Tschan-Plessl, MD, Eivind Heggernes Ask, Thea Johanne Gjerdingen, Michelle Saetersmoen, Hanna Julie Hoel, Merete Thune Wiiger, Msc, Johanna Olweus, Björn E Wahlin, MD PhD, Amir Horowitz, PhD, Todd A Fehniger, MD PhD, Harald Holte, MD PhD, Arne Kolstad, MD PhD, Karl-Johan Malmberg, MD PhD

Blood (2019) 134 (Supplement_1): 2897.

https://doi.org/10.1182/blood-2019-131359

Published: 2019

Journal Articles

Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation

Jeffrey J. Bednarski, MD PhD, Clare Zimmerman, MD, Amanda F Cashen, MD, Sweta Desai, Mark Foster, Tim Schappe, BS, Ethan McClain, Michelle Becker-Hapak, BS, Melissa M Berrien-Elliott, PhD, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 3307.

https://doi.org/10.1182/blood-2019-126982

Published: 2019

Journal Articles

Primary Human NK Cell Gene-Editing Reveals a Critical Role for NKG2A in Cytokine-Induced Memory-like NK Cell Responses

Melissa M Berrien-Elliott, PhD, Wong Pamela, B.S., Carly Neal, B.S., Julia A Wagner, PhD, Michelle Becker-Hapak, BS, Tim Schappe, BS, Matthew L. Cooper, PhD, Emily M Mace, PhD, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 3237.

https://doi.org/10.1182/blood-2019-129162

Published: 2019

Journal Articles

Memory-Like Natural Killer Cells

Melissa M Berrien-Elliott, PhD, Julia A Wagner, BS, Amanda F Cashen, MD, Todd A Fehniger, MD PhD

Blood (2018) 132 (Supplement 1): SCI-8.

https://doi.org/10.1182/blood-2018-99-109537

Published: 2018

Journal Articles

Romidepsin in Combination with Gemcitabine, Oxaliplatin, and Dexamethasone Shows Durable Responses in Aggressive Lymphomas Including AITL and DLBCL: Phase I Results

Neha Mehta-Shah, MD, Peter A Riedell, MD, Nancy L. Bartlett, MD, Amanda F Cashen, MD, Brad S Kahl, MD, Todd A Fehniger, MD PhD, Chaz Moreno, Kenneth R. Carson, MD PhD

Blood (2018) 132 (Supplement 1): 2929.

https://doi.org/10.1182/blood-2018-99-113611

Published: 2018

Journal Articles

Risk Factors for the Development of and Outcomes of Patients Who Develop Severe Cytokine Release Syndrome after Peripheral Blood Haploidentical Donor Transplant

Ramzi Abboud, MD, Michael Slade, BA, Wenners Ballard, III, MD, Jesse Keller, MD, John F DiPersio, MD PhD, Peter Westervelt, MD PhD, Camille N. Abboud, MD, Todd A Fehniger, MD PhD, Kathryn Trinkaus, Rizwan Romee, MD

Blood (2016) 128 (22): 3419.

https://doi.org/10.1182/blood.V128.22.3419.3419

Published: 2016

Journal Articles

Exome Sequencing of Hodgkin's and Non-Hodgkin Composite Lymphomas Identifies Shared Somatic Mutations Indicative of Common Founding Precursors

Felicia Gomez, PhD, Matthew Matlock, BA, Kilannin Krysiak, PhD, Yi-Shan Lee, MD, Eric J. Duncavage, MD, Michelle O'Laughlin, BS, Malachi Griffith, PhD, Todd A Fehniger, MD PhD, Lukas D. Wartman, MD, Obi L. Griffith, PhD

Blood (2016) 128 (22): 5285.

https://doi.org/10.1182/blood.V128.22.5285.5285

Published: 2016

Journal Articles

Human CD56 bright NK Cells Acquire Potent Anti-Leukemia Functionality Following IL-15 Priming

Julia A Wagner, Rizwan Romee, MD, Maximillian Rosario, MDPhD, Melissa M Berrien-Elliott, PhD, Stephanie E Schneider, Jeffrey W Leong, Ryan P Sullivan, PhD, Brea A Jewell, Timothy Schappe, Sara Abdel-Latif, Aaron R Ireland, Devika Jaishankar, Justin A King, Ravi Vij, MD, Todd A Fehniger, MD PhD

Blood (2016) 128 (22): 550.

https://doi.org/10.1182/blood.V128.22.550.550

Published: 2016

Journal Articles

The Use of CD34 + -Selected Stem Cell Boosts Following HLA-Haploidentical Hematopoietic Cell Transplantation

Michael Slade, BA, Scott R Goldsmith, MD, John F DiPersio, MD PhD, Peter Westervelt, MD PhD, Ravi Vij, Todd A Fehniger, MD PhD, Mark A. Schroeder, MD, Rizwan Romee, MD

Blood (2016) 128 (22): 4697.

https://doi.org/10.1182/blood.V128.22.4697.4697

Published: 2016

Journal Articles

T-Cell Replete Peripheral Blood Haploidentical Donor Transplant Is Frequently Associated with Cytokine Release Syndrome Which Responds to Anti-IL-6 Therapy

Ramzi Abboud, MD, Jesse Keller, MD, Michael Slade, BA, Michael P. Rettig, PhD, Stephanie Meier, John F. DiPersio, MD PhD, Todd A Fehniger, MD PhD, Kathryn Trinkaus, Geoffrey L. Uy, MD, Peter Westervelt, MD PhD, Ravi Vij, MD, Camille N. Abboud, MD FACP, Khoan Vu, MD, Pavan Kumar Bhamidipati, MBBS,MD, Rizwan Romee, MD

Blood (2015) 126 (23): 3106.

https://doi.org/10.1182/blood.V126.23.3106.3106

Published: 2015

Journal Articles

Dynamic Changes in Clonal Clearance with Decitabine Therapy in AML and MDS Patients

Blood (2015) 126 (23): 689.

https://doi.org/10.1182/blood.V126.23.689.689

Published: 2015

Journal Articles

Recurrent Somatic Genomic Alterations in Follicular NHL (FL) Revealed By Exome and Custom-Capture Next Generation Sequencing

Todd A Fehniger, MD PhD, Kilannin Krysiak, PhD, Brian S White, PhD, Matthew Matlock, Chris Miller, Robert Fulton, PhD, Friederike Kreisel, MD, Catrina Fronick, Lisa Cook, Joelle Veizer, Amanda F. Cashen, MD, Kenneth R Carson, MD PhD, Melissa M Berrien-Elliott, PhD, Nancy L Bartlett, MD, Richard K Wilson, PhD, Elaine R Mardis, PhD, Timothy J Ley, Malachi Griffith, Obi L Griffith

Blood (2015) 126 (23): 574.

https://doi.org/10.1182/blood.V126.23.574.574

Published: 2015

Journal Articles

Use of Post-Transplant Cyclophosphamide (PTCy) with Mycophenolate Mofetil and Tacrolimus in HLA Matched Allogeneic Hematopoietic Cell Transplant Is Safe and Associated with Acceptable Transplant Outcomes

Brian T Hess, MD, Feng Gao, PhD, John F. DiPersio, MD PhD, Peter Westervelt, MD PhD, Ravi Vij, MD, Geoffrey L. Uy, MD, Keith Stockerl-Goldstein, MD, Camille N. Abboud, MD FACP, Mark A. Schroeder, MD, Iskra Pusic, MD, Armin Ghobadi, MD, Amanda F. Cashen, MD, Todd A Fehniger, MD PhD, Meagan A. Jacoby, MD PhD, Rizwan Romee, MD

Blood (2015) 126 (23): 1950.

https://doi.org/10.1182/blood.V126.23.1950.1950

Published: 2015

Journal Articles

Human Cytokine-Induced Memory-like NK Cells Exhibit in Vivo Anti-Leukemia Activity in Xenografted NSG Mice and in Patients with Acute Myeloid Leukemia (AML)

Rizwan Romee, MD, Rosario Maximillian, MD PhD, Melissa M Berrien-Elliott, PhD, Julia A Wagner, Brea A Jewell, Timothy Schappe, Jeffrey W Leong, Stephanie E Schneider, Sarah Willey, Todd A Fehniger, MD PhD

Blood (2015) 126 (23): 101.

https://doi.org/10.1182/blood.V126.23.101.101

Published: 2015

Journal Articles

'First-in-human' phase I dose escalation trial of IL-15N72D/IL-15Rα-Fc superagonist complex (ALT-803) demonstrates immune activation with anti-tumor activity in patients with relapsed hematological malignancy

Jeffrey S. Miller, MD, Sarah Cooley, MD, Shernan Holtan, Mukta Arora, MD, Celalettin Ustun, MD, Emily Jeng, Hing C. Wong, Michael R. Verneris, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Bruce R. Blazar, MD, Todd A Fehniger, MD PhD, Rizwan Romee, MD

Blood (2015) 126 (23): 1957.

https://doi.org/10.1182/blood.V126.23.1957.1957

Published: 2015

Journal Articles

A Phase I Trial of Brentuximab Vedotin in Combination with Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Jeffrey P. Ward, MDPhD, Jessica Thein, Jingqin Luo, PhD, Nina D. Wagner-Johnston, MD, Amanda F. Cashen, MD, Todd A Fehniger, MD PhD, Nancy L Bartlett, MD

Blood (2015) 126 (23): 3988.

https://doi.org/10.1182/blood.V126.23.3988.3988

Published: 2015

NARROW

Cytokine-Induced Memory-like (ML) NK Cells Persist for > 2 Months Following Adoptive Transfer into Leukemia Patients with a MHC-Compatible Hematopoietic Cell Transplant (HCT)

Romidepsin in Combination with Gemcitabine, Oxaliplatin, and Dexamethasone Shows Durable Responses in Aggressive Lymphomas

Potently Cytotoxic Natural Killer Cell Potential Initially Emerges from Erythro-Myeloid Progenitors during Mammalian Development

Chimeric Antigen Receptor Modified Memory-like (CAR-ML) NK Cells Exhibit Potent Responses to NK-Resistant Tumors

System-Level Disease-Driven Immune Signatures in Patients with Diffuse Large B-Cell Lymphoma Associated with Poor Survival

Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation

Primary Human NK Cell Gene-Editing Reveals a Critical Role for NKG2A in Cytokine-Induced Memory-like NK Cell Responses

Memory-Like Natural Killer Cells

Romidepsin in Combination with Gemcitabine, Oxaliplatin, and Dexamethasone Shows Durable Responses in Aggressive Lymphomas Including AITL and DLBCL: Phase I Results

Risk Factors for the Development of and Outcomes of Patients Who Develop Severe Cytokine Release Syndrome after Peripheral Blood Haploidentical Donor Transplant

Exome Sequencing of Hodgkin's and Non-Hodgkin Composite Lymphomas Identifies Shared Somatic Mutations Indicative of Common Founding Precursors

Human CD56 bright NK Cells Acquire Potent Anti-Leukemia Functionality Following IL-15 Priming

The Use of CD34 + -Selected Stem Cell Boosts Following HLA-Haploidentical Hematopoietic Cell Transplantation

T-Cell Replete Peripheral Blood Haploidentical Donor Transplant Is Frequently Associated with Cytokine Release Syndrome Which Responds to Anti-IL-6 Therapy

Dynamic Changes in Clonal Clearance with Decitabine Therapy in AML and MDS Patients

Recurrent Somatic Genomic Alterations in Follicular NHL (FL) Revealed By Exome and Custom-Capture Next Generation Sequencing

Use of Post-Transplant Cyclophosphamide (PTCy) with Mycophenolate Mofetil and Tacrolimus in HLA Matched Allogeneic Hematopoietic Cell Transplant Is Safe and Associated with Acceptable Transplant Outcomes

Human Cytokine-Induced Memory-like NK Cells Exhibit in Vivo Anti-Leukemia Activity in Xenografted NSG Mice and in Patients with Acute Myeloid Leukemia (AML)

'First-in-human' phase I dose escalation trial of IL-15N72D/IL-15Rα-Fc superagonist complex (ALT-803) demonstrates immune activation with anti-tumor activity in patients with relapsed hematological malignancy

A Phase I Trial of Brentuximab Vedotin in Combination with Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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