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Journal Articles

Pharmaocogenomic Characterization of MCL-1 Inhibitor Response and Resistance in Aggressive B-Cell Lymphomas

Michelle Wang, BSE, Tao Li, MD, Yuan Ren, PhD, Bijal Shah, MD, Tint Lwin, MD PhD, Jing Gao, PhD, Kenneth H. Shain, MD PhD, Wei Zhang, PhD, Xiaohong Zhao, MD PhD, Jianguo Tao, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-141407

Published: 2020

Journal Articles

Re-Constructing and Exploiting Transcriptional Regulatory Networks in Multiple Myeloma Drug Resistance

Rafael Renatino-Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Maria D Coelho Siqueira Silva, MSc, Mark B. Meads, PhD, Alexandre Tungesvik, MD, Gabriel De Avila, Alugubelli Raghunandan Reddy, Minerva Nong, Jamie Teer, PhD, Eric A. Welsh, PhD, Tint Lwin, MD PhD, Amit Kulkarni, PhD, Hongyue Dai, PhD, William S. Dalton, PhDMD, Kenneth H. Shain, MD PhD, Ariosto Siqueira Silva, PhD

Blood (2019) 134 (Supplement_1): 5544.

https://doi.org/10.1182/blood-2019-128442

Published: 2019

Journal Articles

Pharmacoproteomics Identifies PLK1 As Vulnerability for Aggressive B-Cell Lymphomas

Blood (2018) 132 (Supplement 1): 2853.

https://doi.org/10.1182/blood-2018-99-118004

Published: 2018

Journal Articles

Targeting Kinome Reprogramming for Overcoming Ibrutinib-Resistance (IR) in Mantle Cell Lymphoma (MCL)

Xiaohong Zhao, MD PhD, Huijuan Jiang, MD, Michelle Wang, Tao Li, MD, Jing Gao, PhD, Tint Lwin, MD PhD, Yuan Ren, PhD, Eduardo Sotomayor, MD, Bijal D. Shah, MD, Jianguo Tao, MD PhD

Blood (2018) 132 (Supplement 1): 2651.

https://doi.org/10.1182/blood-2018-99-116756

Published: 2018

Journal Articles

Venetoclax As a Single Agent and in Combination with PI3K-mTOR1/2 Kinase Inhibitors Against Ibrutinib Sensitive and Resistant Mantle Cell Lymphoma

Huijuan Jiang, MD, Tint Lwin, MD PhD, Bijal D. Shah, MD, Grace T Li, Yuan Ren, Michael W Yan, Lynn C. Moscinski, MD, Xiaohong Zhao, MD PhD, Jianguo Tao, MD PhD

Blood (2017) 130 (Supplement 1): 5197.

https://doi.org/10.1182/blood.V130.Suppl_1.5197.5197

Published: 2017

Journal Articles

Selective Inhibition of Histone Deacetylase 6 (HDAC6) and HDAC3 As a Novel Therapeutic Strategy in Mantle Cell Lymphoma (MCL)

Fengdong Cheng, MD, Bing Xia, MD, Eva Sahakian, PhD, Tint Lwin, MD PhD, Hongwei Wang, MD, Limin Xing, MD, Bijal D. Shah, MD, Patricio PerezVillarroel, BS, Maritza LienlafMoreno, BS, Yizhuo Zhang, MD, Steven N Quayle, PhD, Simon S Jones, PhD, Javier Pinilla-Ibarz, MD PhD, Alejandro Villagra, PhD, Eduardo M. Sotomayor, MD, Jianguo Tao, MD PhD

Blood (2014) 124 (21): 5397.

https://doi.org/10.1182/blood.V124.21.5397.5397

Published: 2014

Journal Articles

Silencing c-Myc Using Myc Inhibitor JQ1 and EZH2 Inhibitor DZNep Blocks Converging Survival Signals in Aggressive B-Cell Lymphomas

Xiaohong Zhao, PhD, Tint Lwin, MD, PhD, Xinwei Zhang, MD, Andy Huang, Jian Wang, Victor E. Marquez, PhD, Selina Chen-Kiang, PhD, James E Bradner, MD, William S. Dalton, PhD, MD, Eduardo M. Sotomayor, MD, Jianguo Tao, MD, PhD

Blood (2012) 120 (21): 4618.

https://doi.org/10.1182/blood.V120.21.4618.4618

Published: 2012

Journal Articles

Targeting Mir-548m-HDAC6 Axis Circumvents Stroma- Mediated Drug Resistance (CAM-DR) and Clonogenicity in Non-Hodgkin B-Cell Lymphomas

Tint Lwin, MD, PhD, Xiaohong Zhao, PhD, Fengdong Cheng, MD, Xinwei Zhang, MD, Yizhuo Zhang, Andy Huang, Lynn Moscinski, MD, William S. Dalton, PhD, MD, Eduardo M. Sotomayor, MD, Jianguo Tao, MD, PhD

Blood (2012) 120 (21): 5094.

https://doi.org/10.1182/blood.V120.21.5094.5094

Published: 2012

Journal Articles

B Cell Receptor (BCR) Signal Pathways Confer Microenvironment-Mediated Drug Resistance and Are Promising Therapeutic Targets for B Cell Lymphomas

Jiangchuan Tao, Tint Lwin, MD, PhD, Xiaohong Zhao, PhD, Ling Zhang, MD, Lynn Moscinski, MD, Eduardo M. Sotomayor, MD, William S. Dalton, PhD, MD, Jianguo Tao, MD, PhD

Blood (2012) 120 (21): 4918.

https://doi.org/10.1182/blood.V120.21.4918.4918

Published: 2012

Journal Articles

Follicular dendritic cell–dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion–mediated Bim down-regulation through induction of microRNA-181a

Tint Lwin, Jianhong Lin, Yong Sung Choi, Xinwei Zhang, Lynn C. Moscinski, Kenneth L. Wright, Eduardo M. Sotomayor, William S. Dalton, Jianguo Tao

Blood (2010) 116 (24): 5228–5236.

https://doi.org/10.1182/blood-2010-03-275925

Published: 2010

Includes: Supplemental data

Journal Articles

Microenvironment-Mediated Regulation of Micrornas In B-Lymphocytes as a Novel Mechanism for Terminal B-Cell Differentiation and Lymphomagenesis.

Jianhong Lin, M.D, Tint Lwin, MD, PhD, Wayne Tam, MD, PhD, Jian-Jun Zhao, Luis Crespo, Yong Sung Choi, Xinwei Zhang, Victoria Tannenbaum, Eduardo M. Sotomayor, MD, Lynn C. Moscinski, MD, William S. Dalton, PhD, MD, Ken Wright, PhD, Jianguo Tao, MD, PhD

Blood (2010) 116 (21): 3853.

https://doi.org/10.1182/blood.V116.21.3853.3853

Published: 2010

Journal Articles

Microenvironment-Mediated Bim Down-Regulation through Induction of Microrna-181a Protects Cells From Apoptosis In Mantle-Cell and Other Non-Hodgkin B-Cell Lymphomas

Tint Lwin, MD, PhD, Jian-Hong Lin, MD, Yong Sung Choi, MD, PhD, Xinwei Zhang, MD, Lynn Moscinski, MD, Kenneth Wright, PhD, Eduardo M. Sotomayor, MD, William Dalton, PhD, MD, Jianguo Tao, MD, PhD

Blood (2010) 116 (21): 3118.

https://doi.org/10.1182/blood.V116.21.3118.3118

Published: 2010

Journal Articles

Myc Represses miR15a/Mir-16-1 Expression through Recruitment of HDAC3 In Mantle Cell Lymphoma

Xinwei Zhang, MD, Xia Chen, MD, Jianhong Lin, MD, Tint Lwin, MD, PhD, Scott A Ely, MD, Selina Chen-Kiang, MD, William S. Dalton, PhD, MD, Edward Seto, PhD, Kenneth Wright, PhD, Eduardo M. Sotomayor, MD, Jianguo Tao, MD, PhD

Blood (2010) 116 (21): 3121.

https://doi.org/10.1182/blood.V116.21.3121.3121

Published: 2010

Journal Articles

Dysregulation of Micrornas Involved In HTLV-Associated Adult T-Cell Lymphoma

Brady Beltran, MD, Jianhong Lin, M.D., Lubomir Sokol, MD, PhD, Ling Zhang, MD, Tint Lwin, MD, PhD, Jennifer Cultrera, MD, Pilar Quinones, MD, Domingo Morales, MD, Victoria Tannenbaum, Lynn C. Moscinski, MD, Eduardo M. Sotomayor, MD, Jianguo Tao, MD, PhD

Blood (2010) 116 (21): 3122.

https://doi.org/10.1182/blood.V116.21.3122.3122

Published: 2010

Journal Articles

microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma

Jian-Jun Zhao, Jianhong Lin, Tint Lwin, Hua Yang, Jianping Guo, William Kong, Sophie Dessureault, Lynn C. Moscinski, Dorna Rezania, William S. Dalton, Eduardo Sotomayor, Jianguo Tao, Jin Q. Cheng

Blood (2010) 115 (13): 2630–2639.

https://doi.org/10.1182/blood-2009-09-243147

Published: 2010

Includes: Supplemental data

Journal Articles

Follicular Dendritic Cell (FDC)-Induced Microrna-Mediated up-Regulation of PRDM1 and Down-Regulation of BCL6 in Germinal Center B Lymphocytes: A Potential Mechanism for B-Cell Differentiation.

Jianhong Lin, MD, Tint Lwin, MD, PhD, Jianjun Zhao, MD, Jie Zhao, MD, Luis Crespo, BS, Eduardo M. Sotomayor, MD, Lynn C. Moscinski, MD, William S. Dalton, PhD, MD, Ken Wright, PhD, Jianguo Tao, MD, PhD

Blood (2009) 114 (22): 4588.

https://doi.org/10.1182/blood.V114.22.4588.4588

Published: 2009

Journal Articles

MiR-29 MicroRNAs Regulate IGF-1R Expression and Contribute Mantle Cell Lymphoma Growth and Survival.

Jianhong Lin, MD, Jianjun Zhao, MD, Tint Lwin, MD, PhD, Crespo Luis, BS, Fangxia Guan, MD, Sophie Dessureault, MD, PhD, Lynn C. Moscinski, MD, William S. Dalton, PhD, MD, Eduardo M. Sotomayor, MD, Jin Cheng, Jianguo Tao, MD, PhD

Blood (2009) 114 (22): 1957.

https://doi.org/10.1182/blood.V114.22.1957.1957

Published: 2009

Journal Articles

Use of MicroRNA Expression Profiling to Identify Prognostic Subclasses in Mantle Cell Lymphoma: Mir-29 Family as New Prognostic Markers

Jianhong Lin, MD, Jianjun Zhao, MD, PhD, Tint Lwin, MD, PhD, Sophie Dessureault, MD, PhD, Lynn C. Moscinski, MD, William S. Dalton, MD, PhD, Eduardo Sotomayor, MD, Jin Cheng, MD, PhD, Jianguo Tao, MD, PhD

Blood (2008) 112 (11): 3744.

https://doi.org/10.1182/blood.V112.11.3744.3744

Published: 2008

Journal Articles

Cell adhesion induces p27 Kip1 -associated cell-cycle arrest through down-regulation of the SCF Skp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas

Tint Lwin, Lori A. Hazlehurst, Sophie Dessureault, Raymond Lai, Wenlong Bai, Eduardo Sotomayor, Lynn C. Moscinski, William S. Dalton, Jianguo Tao

Blood (2007) 110 (5): 1631–1638.

https://doi.org/10.1182/blood-2006-11-060350

Published: 2007

Journal Articles

Bone Marrow Stroma (BMS) Prevents Apoptosis of Lymphoma Cells by Upregulation of BMS-Derived B-Cell Activating Factor (BAFF) and Activation of NF-kB.

Tint Lwin, MD, PhD, Lori A. Hazlehurst, PhD, Lynn C. Moscinski, MD, William S. Dalton, PhD, MD, Jianguo Tao, MD, PhD

Blood (2006) 108 (11): 2378.

https://doi.org/10.1182/blood.V108.11.2378.2378

Published: 2006

NARROW

Pharmaocogenomic Characterization of MCL-1 Inhibitor Response and Resistance in Aggressive B-Cell Lymphomas

Re-Constructing and Exploiting Transcriptional Regulatory Networks in Multiple Myeloma Drug Resistance

Pharmacoproteomics Identifies PLK1 As Vulnerability for Aggressive B-Cell Lymphomas

Targeting Kinome Reprogramming for Overcoming Ibrutinib-Resistance (IR) in Mantle Cell Lymphoma (MCL)

Venetoclax As a Single Agent and in Combination with PI3K-mTOR1/2 Kinase Inhibitors Against Ibrutinib Sensitive and Resistant Mantle Cell Lymphoma

Selective Inhibition of Histone Deacetylase 6 (HDAC6) and HDAC3 As a Novel Therapeutic Strategy in Mantle Cell Lymphoma (MCL)

Silencing c-Myc Using Myc Inhibitor JQ1 and EZH2 Inhibitor DZNep Blocks Converging Survival Signals in Aggressive B-Cell Lymphomas

Targeting Mir-548m-HDAC6 Axis Circumvents Stroma- Mediated Drug Resistance (CAM-DR) and Clonogenicity in Non-Hodgkin B-Cell Lymphomas

B Cell Receptor (BCR) Signal Pathways Confer Microenvironment-Mediated Drug Resistance and Are Promising Therapeutic Targets for B Cell Lymphomas

Follicular dendritic cell–dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion–mediated Bim down-regulation through induction of microRNA-181a

Microenvironment-Mediated Regulation of Micrornas In B-Lymphocytes as a Novel Mechanism for Terminal B-Cell Differentiation and Lymphomagenesis.

Microenvironment-Mediated Bim Down-Regulation through Induction of Microrna-181a Protects Cells From Apoptosis In Mantle-Cell and Other Non-Hodgkin B-Cell Lymphomas

Myc Represses miR15a/Mir-16-1 Expression through Recruitment of HDAC3 In Mantle Cell Lymphoma

Dysregulation of Micrornas Involved In HTLV-Associated Adult T-Cell Lymphoma

microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma

Follicular Dendritic Cell (FDC)-Induced Microrna-Mediated up-Regulation of PRDM1 and Down-Regulation of BCL6 in Germinal Center B Lymphocytes: A Potential Mechanism for B-Cell Differentiation.

MiR-29 MicroRNAs Regulate IGF-1R Expression and Contribute Mantle Cell Lymphoma Growth and Survival.

Use of MicroRNA Expression Profiling to Identify Prognostic Subclasses in Mantle Cell Lymphoma: Mir-29 Family as New Prognostic Markers

Cell adhesion induces p27 Kip1 -associated cell-cycle arrest through down-regulation of the SCF Skp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas

Bone Marrow Stroma (BMS) Prevents Apoptosis of Lymphoma Cells by Upregulation of BMS-Derived B-Cell Activating Factor (BAFF) and Activation of NF-kB.

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American Society of Hematology

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