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Tim Beissert
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Journal Articles

Overexpression of APC Reduces Stem Cell Capacity and Leukemogenic Potential of PLZF/RAR-Positive Leukemic Stem Cells.

Anita Seshire, PhD, Tim Beissert, PhD, Claudia Oancea, PhD, Dieter Hoelzer, PhD, MD, Martin Ruthardt, MD, Elena Puccetti, PhD
Journal: Blood
Blood (2007) 110 (11): 874.
https://doi.org/10.1182/blood.V110.11.874.874
Published: 2007
Journal Articles

Targeting the Tetramerization by a Specific Peptide Abrogates the Transformation Potential of BCR/ABL and Some of Its Imatinib-Resistant Mutants.

Tim Beissert, Alena Hundertmark, Velina Kaburova, Afsar A. Mian, Lorena Travaglini, Oliver G. Ottmann, Dieter Hoelzer, Clara Nervi, Martin Ruthardt
Journal: Blood
Blood (2006) 108 (11): 2186.
https://doi.org/10.1182/blood.V108.11.2186.2186
Published: 2006
Journal Articles

The Acute Promyelocytic Leukemia-Associated Fusion Proteins PML/RAR and PLZF/RAR Interact with PU.1 and Inactivate Its Transcriptional Function

Anita Seshire, MSc, Tim Beissert, PhD, Dieter Hoelzer, MD, PhD, Martin Ruthardt, MD, Elena Puccetti, PhD
Journal: Blood
Blood (2005) 106 (11): 1603.
https://doi.org/10.1182/blood.V106.11.1603.1603
Published: 2005
Journal Articles

The t(15;17)-Associated Fusion Protein PML/RAR Upregulates c-Kit Which Contributes to the Induction of the Leukemic Phenotype.

Xiaomin Zheng, MSc, Tim Beissert, Brigitte Ruster, Dieter Hoelzer, Reinhard Henschler, Martin Ruthardt
Journal: Blood
Blood (2005) 106 (11): 1608.
https://doi.org/10.1182/blood.V106.11.1608.1608
Published: 2005
Journal Articles

The Acute Promyelocytic Leukemia-Associated Fusion Protein PML/RAR Blocks t-RA-Induced Differentiation in a Subset of Cells with Stem Cell Potential.

Xiaomin Zheng, M.Sc., Anita Seshire, M.Sc., Elena Puccetti, PhD, Hilal Gul, M.Sc., Tim Beissert, PhD, Dieter Hoelzer, M.D., PhD, Oliver G. Ottmann, M.D., Reinhard Henschler, M.D., Martin Ruthardt, M.D.
Journal: Blood
Blood (2004) 104 (11): 1175.
https://doi.org/10.1182/blood.V104.11.1175.1175
Published: 2004
Journal Articles

Valproic Acid Accelerates Cell Cycle Progression of Hematopoietic Stem Cells Via the Activation of GSK3beta-Dependent Signaling Pathways.

Gesine Bug, Hilal Gul, Kerstin Schwarz, Manuela Kampfmann, Xiaomin Zheng, Tim Beissert, Dieter Hoelzer, Oliver G. Ottmann, Martin Ruthardt
Journal: Blood
Blood (2004) 104 (11): 1708.
https://doi.org/10.1182/blood.V104.11.1708.1708
Published: 2004
Journal Articles

γ-Catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells

Xiaomin Zheng, Tim Beissert, Natasa Kukoc-Zivojnov, Elena Puccetti, Joachim Altschmied, Corinna Strolz, Simone Boehrer, Hilal Gul, Orinta Schneider, Oliver Gerhard Ottmann, Dieter Hoelzer, Reinhard Henschler, Martin Ruthardt
Journal: Blood
Blood (2004) 103 (9): 3535–3543.
https://doi.org/10.1182/blood-2003-09-3335
Published: 2004
Journal Articles

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571

Tim Beissert, Elena Puccetti, Andrea Bianchini, Saskia Güller, Simone Boehrer, Dieter Hoelzer, Oliver Gerhard Ottmann, Clara Nervi, Martin Ruthardt
Journal: Blood
Blood (2003) 102 (8): 2985–2993.
https://doi.org/10.1182/blood-2003-03-0811
Published: 2003