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Journal Articles

Donor NK Cell Education By KIR3DL1 and HLA-B Associates with Reduced Relapse in Unrelated Bone Marrow Transplantation for Adult T-Cell Leukemia

Mari Morita-Fujita, Takero Shindo, Shuji Kawaguchi, Kiyotaka Izumi, Yuichi Inadomi, Masakazu Shimizu, Ai Murano, Akiyo Morinibu, Meiko Takahashi, Junya Kanda, Taro Tsujimura, Takuya Yamamoto, Koji Kato, Hidenori Tanaka, Nobuaki Nakano, Tetsuya Eto, Yasuhiko Miyazaki, Kazunori Imada, Youko Suehiro, Toshiro Kawakita, Tatsuo Ichinohe, Takahiro Fukuda, Makoto Onizuka, Yoshiko Atsuta, Fumihiko Matsuda, Akifumi Takaori-Kondo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4982.
https://doi.org/10.1182/blood-2023-185474
Published: 2023
Journal Articles

Impact of Mogamulizumab-Containing Chemotherapy on HBV Reactivation in Patients with T-Cell Lymphoma: A Multicenter Retrospective Observational Study (PROACTIVE-MOGA)

Kisato Nosaka, Shigeru Kusumoto, Yoshitaka Imaizumi, Hiroya Hashimoto, Junya Makiyama, Makoto Yoshimitsu, Takeharu Kato, Hidenori Sasaki, Youko Suehiro, Ki-Ryang Koh, Toyotaka Kawamata, Toshikazu Miyakawa, Yoshifusa Takatsuka, Takayuki Sato, Yuko Shirouchi, Koji Kato, Koji Izutsu, Tohru Murayama, Takehiro Higashi, Hiromi Iwasaki, Satoru Kosugi, Hitoji Uchiyama, Kunihiro Tsukasaki, Yusuke Yamashita, Fumiya Ogasawara, Emiko Sakaida, Takero Shindo, Kimikazu Yakushijin, Keiichi Akizuki, Ken-ichiro Etoh, Noriaki Kawano, Tetsuyuki Igarashi, Noriko Fukuhara, Nobuhiko Nakamura, Isao Yoshida, Nobuaki Nakano, Tomoharu Yoshizumi, Masashi Mizokami
Journal: Blood
Blood (2023) 142 (Supplement 1): 6192.
https://doi.org/10.1182/blood-2023-185878
Published: 2023
Journal Articles

Single-Cell RNA Sequencing Revealed the YY1/EZH2/MLH1 Axis As a Possible Therapeutic Target of Intractable Adult T-Cell Leukemia

Takuya Shimizu, Takero Shindo, Akira Watanabe, Akifumi Takaori-Kondo
Journal: Blood
Blood (2023) 142 (Supplement 1): 6084.
https://doi.org/10.1182/blood-2023-185712
Published: 2023
Journal Articles

Impact of Human Leukocyte Antigen Epitope Matching on Outcomes after Unrelated Bone Marrow Transplantation

Makoto Iwasaki, Junya Kanda, Hidenori Tanaka, Takero Shindo, Noriko Doki, Takahiro Fukuda, Yukiyasu Ozawa, Tetsuya Eto, Naoyuki Uchida, Yuta Katayama, Keisuke Kataoka, Makoto Onizuka, Yoshinobu Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Satoko Morishima
Journal: Blood
Blood (2021) 138 (Supplement 1): 3914.
https://doi.org/10.1182/blood-2021-145686
Published: 2021
Journal Articles

Dual Inhibition of the MEK/ERK and PI3K/AKT Pathways Prevents Pulmonary Graft-Versus-Host Disease through Suppression of Arteriovenous Inflammation and Bronchiolitis

Hiroyuki Muranushi, Takero Shindo, Huong Thi Ngo, Fumiaki Gochi, Akihiko Yoshizawa, Toyofumi Fengshi Chen-Yoshikawa, Akifumi Takaori-Kondo
Journal: Blood
Blood (2021) 138 (Supplement 1): 3807.
https://doi.org/10.1182/blood-2021-148400
Published: 2021
Journal Articles

Graft-Versus-Host Disease-Free, Relapse-Free Survival in Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia/Lymphoma Provides a Novel Donor Selection Paradigm

Hiroyuki Muranushi, MD, Takero Shindo, MD PhD, Masakatsu Hishizawa, MD PhD, Masahito Tokunaga, MD PhD, Atsushi Wake, MD PhD, Nobuaki Nakano, MD, Tetsuya Eto, MD PhD, Michihiro Hidaka, MD PhD, Ilseung Choi, MD PhD, Toshihiro Miyamoto, MD PhD, Naoyuki Uchida, MD PhD, Yukiyoshi Moriuchi, MD, Yasuhiko Miyazaki, MD PhD, Takahiro Fukuda, Tatsuo Ichinohe, Yoshiko Atsuta, MD PhD, Koji Kato, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2008.
https://doi.org/10.1182/blood-2019-123318
Published: 2019
Journal Articles

The MEK Inhibitor Trametinib Enhances Diverse T Cell Reconstitution with Suppressing Xenogeneic Graft-Versus-Host-Disease

Hidekazu Itamura, MD PhD, Hiroyuki Muranushi, MD, Takero Shindo, MD PhD, Kazutaka Kitaura, DVM, PhD, Seiji Okada, MD PhD, Tadasu Shin-I, PhD, Ryuji Suzuki, DVM, PhD, Akifumi Takaori-Kondo, MD PhD, Shinya Kimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1929.
https://doi.org/10.1182/blood-2019-128913
Published: 2019
Journal Articles

Human Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Ameliorate Graft-Versus-Host Disease-Related Manifestations

Sumie Fujii, MD, Yasuo Miura, MD PhD, Aya Fujishiro, MD, Takero Shindo, MD PhD, Yutaka Shimazu, MD, Hideyo Hirai, MD PhD, Akifumi Takaori-Kondo, MD PhD, Tatsuo Ichinohe, MD PhD, Taira Maekawa, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3775.
https://doi.org/10.1182/blood.V130.Suppl_1.3775.3775
Published: 2017
Journal Articles

MEK inhibitors selectively suppress alloreactivity and graft-versus-host disease in a memory stage-dependent manner

Takero Shindo, Tae Kon Kim, Cara L. Benjamin, Eric D. Wieder, Robert B. Levy, Krishna V. Komanduri
Journal: Blood
Blood (2013) 121 (23): 4617–4626.
https://doi.org/10.1182/blood-2012-12-476218
Published: 2013
Includes: Supplemental data
Journal Articles

MEK Inhibitors Selectively Suppress Human T Cell Alloreactivity in a Memory Stage-Dependent Manner,

Takero Shindo, M.D., Ph.D., Tae Kon Kim, M.D., Ph.D., Cara L. Benjamin, Ph.D., Robert B. Levy, Ph.D., Eric D. Wieder, Ph.D., Krishna V. Komanduri, M.D.
Journal: Blood
Blood (2011) 118 (21): 4014.
https://doi.org/10.1182/blood.V118.21.4014.4014
Published: 2011
Journal Articles

The Elevated Ratio of Peripheral Blood CD27−CD4+ T Cells in Patients Received Allogeneic Stem Cell Transplantation Implies Altered T Cell Homeostasis.

Akiko Fukunaga, Takayuki Ishikawa, Takero Shindo, Sumiko Takao, Toshiyuki Hori, Takashi Uchiyama
Journal: Blood
Blood (2005) 106 (11): 1413.
https://doi.org/10.1182/blood.V106.11.1413.1413
Published: 2005
Journal Articles

Interleukin-2-Producing CD4 + OX40 + T Cell as a Target for the Treatment of Chronic Graft-Versus-Host-Disease.

Takero Shindo, MD, Takayuki Ishikawa, MD, PhD, Akiko Fukunaga, MD, Toshiyuki Hori, MD, PhD, Takashi Uchiyama, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 1816.
https://doi.org/10.1182/blood.V106.11.1816.1816
Published: 2005
Journal Articles

Retrospective Analysis of 23 Cases with Human Herpesvirus-6 Associated Encephalitis after Allogeneic Hematopoietic Cell Transplantation.

Takahiro Fukuda, MD, Katsumichi Fujimaki, MD, Shuichi Taniguchi, MD, Masatsugu Tanaka, MD, Hisashi Gondo, MD, Hideki Akiyama, MD, Takero Shindo, MD, Takahiro Karasuno, MD, Satoshi Yoshihara, MD, Jun Ishikawa, MD, Takashi Ashida, MD, Mahito Misawa, MD, Masao Ogata, MD, Ilseung Choi, MD, Atsuo Maruta, MD, Tomoko Kawano, MD, Tomohiro Myojo, MD, Kazuhiro Masuoka, MD, Tsuyoshi Muta, MD, Koji Kato, MD, Hideho Henzan, MD, Takehiko Mori, MD, Masayuki Ikeda, MD, Tetsushi Yoshikawa, MD, Mine Harada, MD
Journal: Blood
Blood (2004) 104 (11): 5067.
https://doi.org/10.1182/blood.V104.11.5067.5067
Published: 2004