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Journal Articles

Obinutuzumab-Based Induction and Maintenance Prolongs Progression-Free Survival (PFS) in Patients with Previously Untreated Follicular Lymphoma: Primary Results of the Randomized Phase 3 GALLIUM Study

Robert E Marcus, Andrew J Davies, FRCP PhD, Kiyoshi Ando, Wolfram Klapper, MD, Stephen Opat, MD, Carolyn J Owen, Elizabeth H Phillips, Randeep Sangha, Rudolf Schlag, John F Seymour, William Townsend, Marek Trněný, Michael K Wenger, Günter Fingerle-Rowson, Kaspar Rufibach, Tom Moore, Michael Herold, Wolfgang Hiddemann, MD
Journal: Blood
Blood (2016) 128 (22): 6.
https://doi.org/10.1182/blood.V128.22.6.6
Published: 2016
Journal Articles

High Major Response Rate, Including Very Good Partial Responses (VGPR), in Patients (pts) with Waldenstrom Macroglobulinemia (WM) Treated with the Highly Specific BTK Inhibitor Bgb-3111: Expansion Phase Results from an Ongoing Phase I Study

Constantine S. Tam, MBBS, Judith Trotman, MBChB, Stephen Opat, MD, Paula Marlton, MBBS, Gavin Cull, MBBS DM FRACP FRCPA, David Simpson, MBChB, FRACP, FRCPA, Matthew Ku, MBBS, David Ritchie, MD PhD, Emma Verner, FRACP, FRCPA, MBBS, Sumita Ratnasingam, MBBS, Mary Ann Anderson, MBBS, Peter Wood, MD FRACP, FRCPA, MBBS, Mark Kirschbaum, MD, Lai Wang, PhD, Ling Xue, Jianxin Yang, Eric Hedrick, John F Seymour, Andrew W. Roberts
Journal: Blood
Blood (2016) 128 (22): 1216.
https://doi.org/10.1182/blood.V128.22.1216.1216
Published: 2016
Journal Articles

Improved Survival of Older Patients with Mantle Cell Lymphoma (MCL) with Front-Line Cytarabine-Based Immunochemotherapy

Sumita Ratnasingam, MBBS, Michael Gilbertson, Zoe McQuilten, MBBS, Kay T Htun, George Grigoriadis, MBBS, PhD BSc, Swe Myo Htet, MBBS, Philip Campbell, MBBS, FRACP, FRCPA, Khai Li Chai, MBBS, Hang Quach, MBBS (Hons), FRACP, FRCPA, MD, Sushrut S. Patil, FRACP, FRCPA, Jake Shortt, MD, Stephen Opat, MD
Journal: Blood
Blood (2016) 128 (22): 2965.
https://doi.org/10.1182/blood.V128.22.2965.2965
Published: 2016
Journal Articles

Safety and Efficacy of Venetoclax and Obinutuzumab in Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL) and Coexisting Medical Conditions: Final Results of the Run-in Phase of the Randomized CLL14 Trial (BO25323)

Kirsten Fischer, MD, Othman Al-Sawaf, MD, Anna-Maria Fink, MD, Mark Dixon, BSc MSC, Jasmin Bahlo, Simon Warburton, MSc, Thomas J. Kipps, MD, PhD, Robert Weinkove, MD PhD, Sue Robinson, MD, Martin H. Dreyling, MD PhD, Stephen Opat, MD, Carolyn J. Owen, MD MDes(UK), FRCPC, Javier López, MD PhD, Kathryn Humphrey, PhD, Rod A. Humerickhouse, MD, Eugen Tausch, Barbara Eichhorst, MD, Clemens-M. Wendtner, MD, Anton W. Langerak, Jacques J.M. van Dongen, MD PhD, Matthias Ritgen, Sebastian Boettcher, MD, Stephan Stilgenbauer, Valentin Goede, MD, Mehrdad Mobasher, MD, Michael Hallek
Journal: Blood
Blood (2016) 128 (22): 2054.
https://doi.org/10.1182/blood.V128.22.2054.2054
Published: 2016
Journal Articles

An International Collaborative Study of Outcome and Prognostic Factors in Patients with Secondary CNS Involvement By Diffuse Large B-Cell Lymphoma

Tarec Christoffer El-Galaly, MD, Chan Yoon Cheah, Mette Dahl Bendtsen, Gita Thanarasjasingam, Roopesh Kansara, Kerry J Savage, MD, Joseph M. Connors, Neta Goldschmidt, MD, Adir Shaulov, Umar Farooq, MD, Laurie H Sehn, MD, Eldad J Dann, Carrie A Thompson, MD, Tsofia Inbar, Brian K Link, MD, Matthew J Maurer, MS, Inger Lise Gade, Maja Bech Juul, Jakob W Hansen, Staffan Holmberg, Thomas S Larsen, Stephen Opat, MD, N George Mikhaeel, John F Seymour, Michael Roost Clausen, MD, Daniel Smith, Michael Gilbertson, Grzegorz S Nowakowski, Sabrina Cordua, Martin Hutchings, Diego Villa
Journal: Blood
Blood (2016) 128 (22): 1874.
https://doi.org/10.1182/blood.V128.22.1874.1874
Published: 2016
Journal Articles

Twice Daily Dosing with the Highly Specific BTK Inhibitor, Bgb-3111, Achieves Complete and Continuous BTK Occupancy in Lymph Nodes, and Is Associated with Durable Responses in Patients (pts) with Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Constantine S. Tam, MBBS, Stephen Opat, MD, Gavin Cull, MBBS DM FRACP FRCPA, Judith Trotman, MBChB, David Gottlieb, MBBS MD FRACP FRCPA, David Simpson, MBChB, FRACP, FRCPA, Paula Marlton, MBBS, Mary Ann Anderson, MBBS, Matthew Ku, MBBS, David Ritchie, MD PhD, Sumita Ratnasingam, MBBS, Bradley Augustson, Mark Kirschbaum, MD, Lai Wang, PhD, Ling Xue, Jianxin Yang, Eric Hedrick, John F Seymour, Andrew W. Roberts
Journal: Blood
Blood (2016) 128 (22): 642.
https://doi.org/10.1182/blood.V128.22.642.642
Published: 2016
Journal Articles

Results of the Safety Run-in Phase of CLL14 (BO25323): A Prospective, Open-Label, Multicenter Randomized Phase III Trial to Compare the Efficacy and Safety of Obinutuzumab and Venetoclax (GDC-0199/ABT-199) with Obinutuzumab and Chlorambucil in Patients with Previously Untreated CLL and Coexisting Medical Conditions

Kirsten Fischer, MD, Anna-Maria Fink, MD, Helen Bishop, Mark Dixon, Jasmin Bahlo, Michael Y. Choi, MD, Robert Weinkove, MD PhD, K. Sue Robinson, MD, Martin Dreyling, MD PhD, Till Seiler, MD, Stephen Opat, MD, Carolyn Owen, MD, Javier Lopez, Sr., MD PhD, Nadine Kutsch, MD, Eugen Tausch, MD, Matthias Ritgen, MD, Rod A. Humerickhouse, MD PhD, Kathryn Humphrey, Michael K. Wenger, MD, Valentin Goede, MD, Barbara Eichhorst, MD, Clemens-Martin Wendtner, MD, Stephan Stilgenbauer, MD, Thomas J. Kipps, MD PhD, Michael Hallek, MD
Journal: Blood
Blood (2015) 126 (23): 496.
https://doi.org/10.1182/blood.V126.23.496.496
Published: 2015
Journal Articles

Head-To-Head Comparison Of Obinutuzumab (GA101) Plus Chlorambucil (Clb) Versus Rituximab Plus Clb In Patients With Chronic Lymphocytic Leukemia (CLL) and Co-Existing Medical Conditions (Comorbidities): Final Stage 2 Results Of The CLL11 Trial

Valentin Goede, MD, Kirsten Fischer, MD, Raymonde Busch, PhD, Anja Engelke, Barbara Eichhorst, MD, Clemens M Wendtner, MD, Tatiana Chagorova, MD, Javier De la Serna, MD, PhD, Marie-Sarah Dilhuydy, MD, Stephen Opat, MD, Carolyn J. Owen, MD, FRCPC, Olga Samoylova, MD, Karl-Anton Kreuzer, MD, Anton W Langerak, PhD, Matthias Ritgen, MD, Stephan Stilgenbauer, MD, Hartmut Döhner, MD, Elina Asikanius, Kathryn Humphrey, Michael K Wenger, MD, Michael Hallek, MD
Journal: Blood
Blood (2013) 122 (21): 6.
https://doi.org/10.1182/blood.V122.21.6.6
Published: 2013
Journal Articles

SAR245409 Monotherapy In Relapsed/Refractory Follicular Lymphoma: Preliminary Results From The Phase II ARD12130 Study

Jennifer R Brown, MD, PhD, Mehdi Hamadani, MD, Jon Arnason, MD, Lionel Karlin, MD, John Hayslip, MD, Nina Wagner-Johnston, MD, Guillaume Cartron, MD, PhD, Vincent Ribrag, Sophie de Guibert, MD, Stephen Opat, MD, Hervé Tilly, MD, Paul Cannell, MBBS, FRCPA, FRACP, Ann Janssens, MD, Fritz Offner, MD, Siddhartha Ganguly, MD, Sikander Ailawadhi, M.D., Michael Millenson, MD, Dominique Bron, MD, PhD, Yi Xu, Rodrigo Ruiz-Soto, MD, MSc, Marie José Kersten, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 86.
https://doi.org/10.1182/blood.V122.21.86.86
Published: 2013
Journal Articles

Azacitidine in Combination with the mTOR Inhibitor Everolimus in Relapsed and Refractory AML

Andrew H Wei, MBBS, PhD, Peter T. Tan, MBBS, John Catalano, MD, Patricia A. Walker, MBBS, FRACP, FRCPA, Anthony P. Schwarer, MD, Sharon Avery, MBBS, Sushrut S. Patil, FRACP FRCPA, Stephen Opat, MD, Nik Cummings, BSc, Andrew Spencer, MD
Journal: Blood
Blood (2011) 118 (21): 2599.
https://doi.org/10.1182/blood.V118.21.2599.2599
Published: 2011
Journal Articles

Whole Transcriptome Sequencing Reveals Recurrent NOTCH1 Mutations in Mantle Cell Lymphoma

Robert Kridel, MD, MPH, Barbara Meissner, PhD, Sanja Rogic, PhD, Merrill Boyle, B.Sc., Adele Telenius, M.Sc., Jay Gunawardana, M.Sc., Chris Cochrane, Arla J Yost, David W Scott, MBChB PhD, King Tan, MBBS, Bruce Woolcock, M.Sc., Susana Ben-Neriah, Stephen Opat, MD, Laurie H. Sehn, MD, MPH, Joseph M. Connors, MD, Andrew P Weng, MD, PhD, Christian Steidl, MD, Randy D. Gascoyne, MD
Journal: Blood
Blood (2011) 118 (21): 436.
https://doi.org/10.1182/blood.V118.21.436.436
Published: 2011
Journal Articles

Molecular Analysis of the SEC23B Gene In Patients Affected by Congenital Dyserythropoietic Anemia Type II (CDAII)

Paola Bianchi, PhD, Klaus Schwarz, MD, Elisa Fermo, PhD, Katja Heinrich, MD, Cristina Vercellati, PhD, Anna Paola Maria Luisa Marcello, PhD, Richard van Wijk, PhD, Rob van Zwieten, MD, Laura Banov, MD, Antonella Sau, MD, Walter A. Wuillemin, MD, Stephen Opat, MD, Wilma Barcellini, MD, Hermann Heimpel, MD, Prof., Alberto Zanella, MD
Journal: Blood
Blood (2010) 116 (21): 4227.
https://doi.org/10.1182/blood.V116.21.4227.4227
Published: 2010
Journal Articles

Whole Brain Radiotherapy and Ara-C In Consolidation Post High-Dose Methotrexate Is Important In Establishing Durable Disease Control In the Treatment of Primary CNS Lymphoma: A Single Centre Observational Study

Hang Quach, MBBS, FRACP, FRCPA, MD, Melody Abikhair, Michael MacManus, MBBS, MD, Ron Freilich, MBBS, FRACP, Beena Kumar, Ian Simpson, Stephen Opat, MD
Journal: Blood
Blood (2010) 116 (21): 1776.
https://doi.org/10.1182/blood.V116.21.1776.1776
Published: 2010