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Journal Articles

PRMT5 Inhibition Selectively Targets Acute Myeloid Leukemia Stem Cells Though a p53-Dependent Mechanism

Emma Toulmin, PhD, Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Andrej Terzic, BSc, Feng Yan, BSc, Nicholas Wong, PhD, Ian Street, PhD, Paul Stupple, PhD, Stephen Jane, MD PhD, Andrew H Wei, MBBS, PhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4061.
https://doi.org/10.1182/blood-2018-99-117835
Published: 2018
Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 53.
https://doi.org/10.1182/blood-2018-99-118406
Published: 2018
Journal Articles

The TAL1/SCL Transcription Factor Regulates Cell-Cycle Progression in Murine Monocyte-Macrophage Precursors.

Soumyadeep Dey, M.S., David J. Curtis, MD, PhD, Stephen Jane, MD, PhD, Stephen J. Brandt, MD
Journal: Blood
Blood (2009) 114 (22): 570.
https://doi.org/10.1182/blood.V114.22.570.570
Published: 2009
Journal Articles

Context-Specific KLF-1 Mediated Transcriptional Activation at the Alpha Hemoglobin-Stabilizing Protein and Dematin Promoters in Erythroid Cells.

Aurelie Desgardin, Valerie M. Jansen, Eun-Hee Shim, PHD, Tatiana Abramova, Shaji Ramachandran, PHD, Stephen Jane, MD, PhD, John M Cunningham, MD
Journal: Blood
Blood (2009) 114 (22): 461.
https://doi.org/10.1182/blood.V114.22.461.461
Published: 2009
Journal Articles

Novel Role of the TAL1/SCL Transcription Factor in Murine Monocytopoiesis.

Soumyadeep Dey, M.S., David J. Curtis, MD, PhD, Stephen Jane, MD, PhD, Stephen J. Brandt, MD
Journal: Blood
Blood (2008) 112 (11): 1376.
https://doi.org/10.1182/blood.V112.11.1376.1376
Published: 2008
Journal Articles

Altered Erythroid and Megakaryocytic Differentiation in Mice Expressing a Unique Chromatin Remodeling Domain of Erythroid Krüppel-Like Factor (EKLF)

Valerie M. Jansen, Tatiana Abramova, Eun-Hee Shim, PhD, Shaji Ramachandran, PhD, Aurelie Desgardin, Vishwas Parekh, Stephen Jane, MD, PhD, John M Cunningham, MD
Journal: Blood
Blood (2008) 112 (11): 132.
https://doi.org/10.1182/blood.V112.11.132.132
Published: 2008
Journal Articles

The Protein Methyltransferase Prmt5 Links Histone H4 Methylation to Dnmt3a-Dependent DNA Methylation and Transcriptional Silencing of the Fetal Globin Genes.

Stephen Jane, MD, PhD, Quan Zhao, PhD, Gerhard Rank, PhD, Loretta Cerruti, BSc, David J. Curtis, MD, PhD, John M. Cunningham, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 361.
https://doi.org/10.1182/blood.V108.11.361.361
Published: 2006
Journal Articles

Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from EKLF null mice

Elise Coghill, Sarah Eccleston, Vanessa Fox, Loretta Cerruti, Clark Brown, John Cunningham, Stephen Jane, Andrew Perkins
Journal: Blood
Blood (2001) 97 (6): 1861–1868.
https://doi.org/10.1182/blood.V97.6.1861
Published: 2001