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Journal Articles

Pre-Clinical Validation of a Novel Erk1/2 and CDK4/6 Inhibitor Combination in Multiple Myeloma (MM)

Sophia Adamia, PhD, Shruti Bhatt, PhD, Yu-Tzu Tai, PhD, Kenneth Wen, Catherine A Nicholas, Marissa S Pioso, Ivane Abiatari, MD, Anthony G. Letai, MD PhD, Kenneth Anderson, MD

Blood (2020) 136 (Supplement 1): 22–23.

https://doi.org/10.1182/blood-2020-142596

Published: 2020

Journal Articles

Exploring POU2AF1 ( BOB-1 ) D ependency and Transcription Addiction in Multiple Myeloma

Zuzana Chyra, PhD, Mehmet Kemal Samur, PhD, Anil Aktas-Samur, PhD, Yan Xu, MD, Eugenio Morelli, MD, Sophia Adamia, PhD, Woojun D Park, Lin Charles, PhD, Masood A. Shammas, PhD, Roman Hajek, MD PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 49.

https://doi.org/10.1182/blood-2020-142587

Published: 2020

Journal Articles

Aberrant RHAMM Splicing in Multiple Myeloma (MM) and Its Implications for Immunotherapy

Daisuke Ogiya, MD PhD, Lisa Müller, Sigitas J Verselis, PhD, Heiner Schaal, PhD, Ivane Abiatari, MD, Ana M Stenstrom, Catherine A Nicholas, John F Daley, Michael P. Chu, David M. Dorfman, MD PhD, Linda M. Pilarski, PhD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD, Sophia Adamia, PhD

Blood (2019) 134 (Supplement_1): 1804.

https://doi.org/10.1182/blood-2019-131775

Published: 2019

Journal Articles

Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

Sophia Adamia, PhD, Daisuke Ogiya, MD PhD, Ivane Abiatari, MD, Sigitas J Verselis, PhD, Michael P. Chu, David M. Dorfman, MD PhD, Linda M. Pilarski, PhD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 3079.

https://doi.org/10.1182/blood-2019-131243

Published: 2019

Journal Articles

Individualized Mitochondrial Functional Approach to Combination of BCL-2 and MCL-1 Antagonism in Acute Myeloid Leukemia

Shruti Bhatt, PhD, Marissa Pioso, Elyse Ann Olesinski, Binyam Yilma, Leutz Buon, Sophia Adamia, PhD, Holly Zhu, Jeremy Ryan, Youzhen Wang, Morris Erick, Ensar Halilovic, David M. Weinstock, MD, Jacqueline S Garcia, MD, Anthony Letai

Blood (2019) 134 (Supplement_1): 2551.

https://doi.org/10.1182/blood-2019-131101

Published: 2019

Journal Articles

Cell Type-Specific Deregulation of Polypyrimidine Tract- Binding Proteins (PTBPs) Drive Aberrant Splicing in Multiple Myeloma (MM) and Acute Myeloid Leukemia (AML)

Sophia Adamia, PhD, Sigitas J Verselis, PhD, Teru Hideshima, MD PhD, Michael P. Chu, MD, Shruti Bhatt, PhD, David P. Steensma, MD, Daniel J Deangelo, Richard M. Stone, MD, Daniel G. Tenen, MD, Linda M. Pilarski, PhD, James D. Griffin, MD, Kenneth Anderson, MD

Blood (2018) 132 (Supplement 1): 3895.

https://doi.org/10.1182/blood-2018-99-118501

Published: 2018

Journal Articles

A Functional Approach to Precision Medicine Identifies Targeted Therapies for Acute Myeloid Leukemia

Shruti Bhatt, PhD, Vineeth Kumar Murali, Holly Zhu, Sophia Adamia, PhD, Amanda L Christie, BS, David M. Weinstock, MD, Jackie S Garcia, MD, Anthony Letai, MD PhD

Blood (2017) 130 (Supplement 1): 853.

https://doi.org/10.1182/blood.V130.Suppl_1.853.853

Published: 2017

Journal Articles

Identification Cause of Aberrant Splicing and Novel Drug Targets in Patients with Multiple Myeloma

Sophia Adamia, PhD, Teru Hideshima, MD PhD, Kenneth C Anderson, MD

Blood (2017) 130 (Supplement 1): 4340.

https://doi.org/10.1182/blood.V130.Suppl_1.4340.4340

Published: 2017

Journal Articles

FLT3 Splice Variant (FLT3Va) As a Potential Immunotherapeutic Target in Patients with Acute Myeloid Leukemia (AML)

Sophia Adamia, PhD, Jeffrey Nemeth, PhD, Shruti Bhatt, PhD, Sarah R Walker, Natalie I Voeks, William Lento, PhD, Ricardo M. Attar, Ilene Galinsky, MSN, ANPc, David A Frank, MD PhD, Martha Wadleigh, MD, Anthony Letai, MD PhD, David P. Steensma, MD, David M. Weinstock, MD, Daniel J. DeAngelo, MD PhD, David M. Dorfman, MD PhD, Richard M. Stone, MD, James D Griffin, MD

Blood (2016) 128 (22): 1681.

https://doi.org/10.1182/blood.V128.22.1681.1681

Published: 2016

Journal Articles

Use of 2HG Levels in the Serum, Urine, or Bone Marrow to Predict IDH Mutations in Adults with Acute Myeloid Leukemia

Andrew M. Brunner, MD, Donna S Neuberg, ScD, Seth A. Wander, MD PhD, Hossein Sadrzadeh, MD, Karen K. Ballen, MD, Philip C. Amrein, MD, Gabriela S. Hobbs, MD, Yi-Bin Chen, MD, Ashley M. Perry, BS, Christelle Joseph, Meghan E. Burke, Aura Y Ramos, Regina Silver, Ilene Galinsky, ANP, Sophia Adamia, PhD, Darrell Borger, PhD, Anthony J Iafrate, MD PhD, Richard M. Stone, MD, Amir T. Fathi, MD

Blood (2015) 126 (23): 2597.

https://doi.org/10.1182/blood.V126.23.2597.2597

Published: 2015

Journal Articles

A Novel Synthetic Lethal Approach Targeting SIRT6 in Acute Myeloid Leukemia

Michele Cea, MD, Antonia Cagnetta, MD, Davide Lovera, MD, Raffaella Grasso, PhD, Nicoletta Colombo, PhD, Micaela Bergamaschi, MD, Sara Aquino, MD, Fabio Guolo, MD, Paola Minetto, MD, Filippo Ballerini, MD, Letizia Canepa, MD, Sophia Adamia, PhD, Alessio Nencioni, Ivana Pierri, MD, Marino Clavio, Maurizio Miglino, PhD, Marco Gobbi, MD, Roberto Massimo Lemoli, MD

Blood (2015) 126 (23): 1375.

https://doi.org/10.1182/blood.V126.23.1375.1375

Published: 2015

Journal Articles

IDH1 Splicing Alterations in Patients with AML and Their Relationship to Blood 2HG Levels

Sophia Adamia, PhD, Patricia Toniolo, PhDcandidate, Amir T. Fathi, MD, Ilene Galinsky, ANP, Suiyang Liu, Katharine Yen, Hyeryun Kim Kim, Dongwei Zhu, Straley Kim, Martha Wadleigh, MD, David P. Steensma, MD, Ibiayi Dagogo-Jack, MD, Daniel J. DeAngelo, MD PhD, James D. Griffin, MD, Richard M. Stone, MD

Blood (2014) 124 (21): 1060.

https://doi.org/10.1182/blood.V124.21.1060.1060

Published: 2014

Journal Articles

IL-17A-Mediated Notch Signaling in Multiple Myeloma

Rao H. Prabhala, PhD, Teru Hideshima, MD PhD, Mariateresa Fulciniti, PhD, Sophia Adamia, PhD, Rajya Lakshmi Bandi, BS, Puru Nanjappa, MS, Kenneth C. Anderson, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3434.

https://doi.org/10.1182/blood.V124.21.3434.3434

Published: 2014

Journal Articles

Mir-23b Plays a Critical Role As a Tumor Suppressor miRNA In Multiple Myeloma

Mariateresa Fulciniti, PhD, Nicola Amodio, PhD, Rajya Bandi, Rao H. Prabhala, Ph.D., Sophia Adamia, PhD, Teresa Calimeri, MD, Lavinia Biamonte, PhD, Marzia Leotta, MD, Kenneth C. Anderson, MD, Pierfrancesco Tassone, MD, Munshi C Nikhil, MD

Blood (2013) 122 (21): 122.

https://doi.org/10.1182/blood.V122.21.122.122

Published: 2013

Journal Articles

Aberrant Splicing In Patients With AML Is Associated With Over- Expression Of Specific Splicing Factors

Sophia Adamia, PhD, Christian Bach, Ph.D., Patrick M Pilarski, Martha Wadleigh, MD, David P. Steensma, MD, Gabriela Motyckova, MD, PhD, Daniel J. DeAngelo, MD, Ph.D, Richard M. Stone, MD, Daniel G. Tenen, MD, James D. Griffin, MD

Blood (2013) 122 (21): 3749.

https://doi.org/10.1182/blood.V122.21.3749.3749

Published: 2013

Journal Articles

Non Homologous End Joining, a Marker Of Genomic Instability Is Elevated In Multiple Myeloma: A New Prognostic Factor

Teresa Calimeri, MD, Mehmet Kemal Samur, PhD, Nicola Amodio, PhD, Michele Cea, MD, Antonia Cagnetta, MD, Mariateresa Fulciniti, PhD, Sophia Adamia, PhD, Marco Rossi, MD, Yu-Tzu Tai, PhD, Fortunato Morabito, MD, Abdel Kareem Azab, BPharm, PhD, Stephane Minvielle, PhD, Herve Avet-Loiseau, MD, Cheng Li, PhD, Jean-Bernard Lazaro, PhD, Kenneth C. Anderson, Masood A. Shammas, Pierfrancesco Tassone, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 124.

https://doi.org/10.1182/blood.V122.21.124.124

Published: 2013

Journal Articles

Identification Of Novel Alternative Splice Variants Of Sirtuins In Multiple Myeloma: Therapeutic Implications

Antonia Cagnetta, MD, Michele Cea, MD, Sophia Adamia, PhD, Yu-Tzu Tai, PhD, Teru Hideshima, MD, PhD, Marco Gobbi, MD, Nikhil C. Munshi, MD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2013) 122 (21): 3121.

https://doi.org/10.1182/blood.V122.21.3121.3121

Published: 2013

Journal Articles

Formation of the Functional Niche in Vitro by Mimicking the Pathophysiological Features of the Bone Marrow Microenvironment in Multiple Myeloma

Jana Jakubikova, PhD, Richard W.J. Groen, PhD, Sophia Adamia, PhD, Teru Hideshima, MD, PhD, Danka Cholujova, PhD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD

Blood (2012) 120 (21): 1812.

https://doi.org/10.1182/blood.V120.21.1812.1812

Published: 2012

Journal Articles

Aberrant Non-Homologous End Joining in Multiple Myeloma: A Role in Genomic Instability and As Potential Prognostic Marker.

Blood (2012) 120 (21): 2932.

https://doi.org/10.1182/blood.V120.21.2932.2932

Published: 2012

Journal Articles

Genome-Wide Aberrant Splicing in Patients with Acute Myelold Leukemia (AML) Is Associated with Altered Expression of Splicing Factors

Sophia Adamia, PhD, Hervé Avet-Loiseau, MD, PhD, Jana Jakubikova, Suzan Lazo-Kallanian, John Daley, PhD, Laurence Lode, Ph.D, Ilene Galinsky, ANP, Richard M. Stone, MD, James D. Griffin, MD

Blood (2012) 120 (21): 652.

https://doi.org/10.1182/blood.V120.21.652.652

Published: 2012

NARROW

Pre-Clinical Validation of a Novel Erk1/2 and CDK4/6 Inhibitor Combination in Multiple Myeloma (MM)

Exploring POU2AF1 ( BOB-1 ) D ependency and Transcription Addiction in Multiple Myeloma

Aberrant RHAMM Splicing in Multiple Myeloma (MM) and Its Implications for Immunotherapy

Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

Individualized Mitochondrial Functional Approach to Combination of BCL-2 and MCL-1 Antagonism in Acute Myeloid Leukemia

Cell Type-Specific Deregulation of Polypyrimidine Tract- Binding Proteins (PTBPs) Drive Aberrant Splicing in Multiple Myeloma (MM) and Acute Myeloid Leukemia (AML)

A Functional Approach to Precision Medicine Identifies Targeted Therapies for Acute Myeloid Leukemia

Identification Cause of Aberrant Splicing and Novel Drug Targets in Patients with Multiple Myeloma

FLT3 Splice Variant (FLT3Va) As a Potential Immunotherapeutic Target in Patients with Acute Myeloid Leukemia (AML)

Use of 2HG Levels in the Serum, Urine, or Bone Marrow to Predict IDH Mutations in Adults with Acute Myeloid Leukemia

A Novel Synthetic Lethal Approach Targeting SIRT6 in Acute Myeloid Leukemia

IDH1 Splicing Alterations in Patients with AML and Their Relationship to Blood 2HG Levels

IL-17A-Mediated Notch Signaling in Multiple Myeloma

Mir-23b Plays a Critical Role As a Tumor Suppressor miRNA In Multiple Myeloma

Aberrant Splicing In Patients With AML Is Associated With Over- Expression Of Specific Splicing Factors

Non Homologous End Joining, a Marker Of Genomic Instability Is Elevated In Multiple Myeloma: A New Prognostic Factor

Identification Of Novel Alternative Splice Variants Of Sirtuins In Multiple Myeloma: Therapeutic Implications

Formation of the Functional Niche in Vitro by Mimicking the Pathophysiological Features of the Bone Marrow Microenvironment in Multiple Myeloma

Aberrant Non-Homologous End Joining in Multiple Myeloma: A Role in Genomic Instability and As Potential Prognostic Marker.

Genome-Wide Aberrant Splicing in Patients with Acute Myelold Leukemia (AML) Is Associated with Altered Expression of Splicing Factors

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American Society of Hematology

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American Society of Hematology

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