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Sarah R Walker
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Journal Articles

A Clinical Trial of the STAT3 Inhibitor Pyrimethamine in Chronic Lymphocytic Leukemia

Jennifer R. Brown, MD PhD, Sarah R. Walker, PhD, Lisa N. Heppler, Svitlana Tyekucheva, Erik Nelson, PhD, Josephine L. Klitgaard, MSc, PhD, Maria Nicolais, MD, Yasmin Kroll, Michael Xiang, MD PhD, Jennifer E. Yeh, MD PhD, Mousumi Chaudhury, Zachary T. Giaccone, Stacey Fernandes, Jeffrey G. Supko, PhD, Catherine J. Wu, MD, David A. Frank, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1855.
https://doi.org/10.1182/blood-2018-99-118921
Published: 2018
Journal Articles

FLT3 Splice Variant (FLT3Va) As a Potential Immunotherapeutic Target in Patients with Acute Myeloid Leukemia (AML)

Sophia Adamia, PhD, Jeffrey Nemeth, PhD, Shruti Bhatt, PhD, Sarah R Walker, Natalie I Voeks, William Lento, PhD, Ricardo M. Attar, Ilene Galinsky, MSN, ANPc, David A Frank, MD PhD, Martha Wadleigh, MD, Anthony Letai, MD PhD, David P. Steensma, MD, David M. Weinstock, MD, Daniel J. DeAngelo, MD PhD, David M. Dorfman, MD PhD, Richard M. Stone, MD, James D Griffin, MD
Journal: Blood
Blood (2016) 128 (22): 1681.
https://doi.org/10.1182/blood.V128.22.1681.1681
Published: 2016
Journal Articles

Gene expression–based discovery of atovaquone as a STAT3 inhibitor and anticancer agent

Michael Xiang, Haesook Kim, Vincent T. Ho, Sarah R. Walker, Michal Bar-Natan, Melodi Anahtar, Suhu Liu, Patricia A. Toniolo, Yasmin Kroll, Nichole Jones, Zachary T. Giaccone, Lisa N. Heppler, Darwin Q. Ye, Jason J. Marineau, Daniel Shaw, James E. Bradner, Traci Blonquist, Donna Neuberg, Claudio Hetz, Richard M. Stone, Robert J. Soiffer, David A. Frank
Journal: Blood
Blood (2016) 128 (14): 1845–1853.
https://doi.org/10.1182/blood-2015-07-660506
Published: 2016
Includes: Supplemental data
Journal Articles

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors

Erik A. Nelson, Sarah R. Walker, Ellen Weisberg, Michal Bar-Natan, Rosemary Barrett, Laurie B. Gashin, Shariya Terrell, Josephine L. Klitgaard, Loredana Santo, Martha R. Addorio, Benjamin L. Ebert, James D. Griffin, David A. Frank
Journal: Blood
Blood (2011) 117 (12): 3421–3429.
https://doi.org/10.1182/blood-2009-11-255232
Published: 2011
Includes: Supplemental data
Journal Articles

Inhibition of Both Jak2 and STAT5 Enhances Toxicity to Myeloproliferative Cells.

Michal Bar-Natan, M.D, Erik A. Nelson, PhD, Sarah R. Walker, Ph.D., Rosemary Barrett, B.S., David A. Frank, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1905.
https://doi.org/10.1182/blood.V114.22.1905.1905
Published: 2009
Journal Articles

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3

Erik A. Nelson, Sarah R. Walker, Alicia Kepich, Laurie B. Gashin, Teru Hideshima, Hiroshi Ikeda, Dharminder Chauhan, Kenneth C. Anderson, David A. Frank
Journal: Blood
Blood (2008) 112 (13): 5095–5102.
https://doi.org/10.1182/blood-2007-12-129718
Published: 2008
Includes: Supplemental data
Journal Articles

Pimozide Inhibits STAT5 Signaling in Chronic Myelogenous Leukemia and Reduces the Viability of Both Imatinib Sensitive and Imatinib Resistant Cells.

Erik A. Nelson, PhD, Sarah R. Walker, Ph.D., Alicia Kepich, B.S., Shariya Terrell, B.S., Laurie Gashin, B.S., David A. Frank, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 2953.
https://doi.org/10.1182/blood.V110.11.2953.2953
Published: 2007
Journal Articles

Nifuroxazide Inhibits STAT3 Function and Shows Potent Anti-Tumor Activity Against Multiple Myeloma.

Erik A. Nelson, PhD, Teru Hideshima, M.D. Ph.D, Laurie Gashin, Sarah R. Walker, B.S., Rebecca A. Lynch, B.S., Dharminder Chauhan, Ph.D., Kenneth C. Anderson, M.D., David A. Frank, M.D.,Ph.D.
Journal: Blood
Blood (2006) 108 (11): 3450.
https://doi.org/10.1182/blood.V108.11.3450.3450
Published: 2006