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Erik A. Nelson
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Journal Articles

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors

Erik A. Nelson, Sarah R. Walker, Ellen Weisberg, Michal Bar-Natan, Rosemary Barrett, Laurie B. Gashin, Shariya Terrell, Josephine L. Klitgaard, Loredana Santo, Martha R. Addorio, Benjamin L. Ebert, James D. Griffin, David A. Frank
Journal: Blood
Blood (2011) 117 (12): 3421–3429.
https://doi.org/10.1182/blood-2009-11-255232
Published: 2011
Includes: Supplemental data
Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity

Loredana Santo, MD, Teru Hideshima, MD, PhD, Diana Cirstea, MD, Madhavi L Bandi, PhD, Erik A Nelson, PhD, Hiroshi Ikeda, MD, Sonia Vallet, MD, Samantha Pozzi, MD, Kishan Patel, Gullu Gorgun, PhD, Naoya Mimura, MD, Claire Fabre, MD, Yiguo Hu, PhD, Dharminder Chauhan, PhD, Matthew S Squires, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Noopur Raje, MD
Journal: Blood
Blood (2010) 116 (21): 2994.
https://doi.org/10.1182/blood.V116.21.2994.2994
Published: 2010
Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

Loredana Santo, M.D., Teru Hideshima, MD., Ph.D., Erik A. Nelson, Ph.D, Diana Cirstea, MD, Madhavi Bandi, Ph.D, Hiroshi Ikeda, MD, PhD, Gullu Gorgun, PhD, Sonia Vallet, MD., Samantha Pozzi, MD, Giulia Perrone, MD, Kishan Patel, Yiguo Hu, Ph.D, Matthew S Squires, Murray Yule, Elisabetta Calabrese, MD., Dharminder Chauhan, Ph.D, Nikhil C. Munshi, Kenneth C. Anderson, MD, Noopur Raje, MD.
Journal: Blood
Blood (2009) 114 (22): 3833.
https://doi.org/10.1182/blood.V114.22.3833.3833
Published: 2009
Journal Articles

Inhibition of Both Jak2 and STAT5 Enhances Toxicity to Myeloproliferative Cells.

Michal Bar-Natan, M.D, Erik A. Nelson, PhD, Sarah R. Walker, Ph.D., Rosemary Barrett, B.S., David A. Frank, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1905.
https://doi.org/10.1182/blood.V114.22.1905.1905
Published: 2009
Journal Articles

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3

Erik A. Nelson, Sarah R. Walker, Alicia Kepich, Laurie B. Gashin, Teru Hideshima, Hiroshi Ikeda, Dharminder Chauhan, Kenneth C. Anderson, David A. Frank
Journal: Blood
Blood (2008) 112 (13): 5095–5102.
https://doi.org/10.1182/blood-2007-12-129718
Published: 2008
Includes: Supplemental data
Journal Articles

Pimozide Inhibits STAT5 Signaling in Chronic Myelogenous Leukemia and Reduces the Viability of Both Imatinib Sensitive and Imatinib Resistant Cells.

Erik A. Nelson, PhD, Sarah R. Walker, Ph.D., Alicia Kepich, B.S., Shariya Terrell, B.S., Laurie Gashin, B.S., David A. Frank, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 2953.
https://doi.org/10.1182/blood.V110.11.2953.2953
Published: 2007
Journal Articles

Nifuroxazide Inhibits STAT3 Function and Shows Potent Anti-Tumor Activity Against Multiple Myeloma.

Erik A. Nelson, PhD, Teru Hideshima, M.D. Ph.D, Laurie Gashin, Sarah R. Walker, B.S., Rebecca A. Lynch, B.S., Dharminder Chauhan, Ph.D., Kenneth C. Anderson, M.D., David A. Frank, M.D.,Ph.D.
Journal: Blood
Blood (2006) 108 (11): 3450.
https://doi.org/10.1182/blood.V108.11.3450.3450
Published: 2006
Journal Articles

IL-2 regulates FOXP3 expression in human CD4 + CD25 + regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

Emmanuel Zorn, Erik A. Nelson, Mehrdad Mohseni, Fabrice Porcheray, Haesook Kim, Despina Litsa, Roberto Bellucci, Elke Raderschall, Christine Canning, Robert J. Soiffer, David A. Frank, Jerome Ritz
Journal: Blood
Blood (2006) 108 (5): 1571–1579.
https://doi.org/10.1182/blood-2006-02-004747
Published: 2006
Journal Articles

IL-2 Therapy Promotes the Expansion of Human CD4+CD25+ Regulatory T Cells and Selectively Upregulates the Expression of FOXP3 in T Cells In Vivo.

Emmanuel Zorn, PhD, Erik A. Nelson, PhD, Mehrdad Mohseni, MD, Despina Litsa, BSc, Haesook Kim, PhD, Roberto Bellucci, PhD, Fabrice Porcheray, PharmD, Christine Canning, MD, Robert J. Soiffer, MD, Jerome Ritz, MD
Journal: Blood
Blood (2005) 106 (11): 1257.
https://doi.org/10.1182/blood.V106.11.1257.1257
Published: 2005
Journal Articles

The amino terminal and E2F interaction domains are critical for C/EBPα-mediated induction of granulopoietic development of hematopoietic cells

Francesco D'Alo', Lisa M. Johansen, Erik A. Nelson, Hanna S. Radomska, Erica K. Evans, Pu Zhang, Claus Nerlov, Daniel G. Tenen
Journal: Blood
Blood (2003) 102 (9): 3163–3171.
https://doi.org/10.1182/blood-2003-02-0479
Published: 2003