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Journal Articles

Chick embryo xenograft model of multiple myeloma recapitulates immune response, systemic dissemination, and sensitivity to anti-myeloma therapeutics

Izabela Cymer, Cerelia Yoong, Catherine Richards, Roisin McAvera, Hanne Jahns, Lance Hudson, Joanna Fay, Katherine Sheehan, Siobhan Glavey, Ann Hopkins

Blood (2025) 146 (Supplement 1): 5082.

https://doi.org/10.1182/blood-2025-5082

Published: 2025

Journal Articles

JAM(A), a chromosome 1q adhesion protein, is overexpressed in 1q amplified myeloma and may represent a novel therapeutic target for high-risk disease.

Niamh McCauley, Lara Donnelly, Roisin McAvera, Joanna Fay, Lance Hudson, Marian Brennan, Marc Devocelle, John Quinn, Philip Murphy, Ann Hopkins, Siobhan Glavey

Blood (2025) 146 (Supplement 1): 5079.

https://doi.org/10.1182/blood-2025-5079

Published: 2025

Journal Articles

Phase 1b study of cyclophosphamide, pomalidomide, dexamethasone, and daratumumab (CPD-DARA) in relapsed/refractory multiple myeloma: Safety and efficacy in a heavily pretreated population

Blood (2025) 146 (Supplement 1): 4031.

https://doi.org/10.1182/blood-2025-4031

Published: 2025

Journal Articles

Isatuximab (Isa) plus lenalidomide (R), Bortezomib (V), and dexamethasone (d) (Isa-RVd) as induction therapy in transplant-eligible patients (pts) with newly diagnosed multiple myeloma (NDMM): Primary analysis of parallel phase 2 studies by the Dana-Farber Cancer Institute (DFCI) and Cancer Trials Ireland (CTI)

Blood (2025) 146 (Supplement 1): 4030.

https://doi.org/10.1182/blood-2025-4030

Published: 2025

Journal Articles

Genomic and transcriptomic signatures of extramedullary multiple myeloma reveal possible drivers of therapeutic resistance

Catherine Duane, Tony O'Grady, Sahin Sarihan, Izabela Cymer, Michael O'Dwyer, Adam Roche, Philip Murphy, John Quinn, Siobhan Glavey

Blood (2025) 146 (Supplement 1): 2175.

https://doi.org/10.1182/blood-2025-2175

Published: 2025

Journal Articles

Acute Abdominal and Pelvic Complications in Patients with Non-Promyelocytic Acute Myeloid Leukaemia Undergoing Intensive Induction Chemotherapy Are Associated with Favorable Prognosis

Philip T Murphy, Mohammed Alsaleh, Harris Cheema, Quinn John, Siobhan Glavey, Jeremy Sargent, Dawn Jennifer Swan

Blood (2023) 142 (Supplement 1): 5858.

https://doi.org/10.1182/blood-2023-178204

Published: 2023

Journal Articles

Red Blood Cells from COVID-19 Patients Show Evidence of Increased Oxidative Stress and Increased Lactate Influx

Philip Murphy, Edel Mullen, Stephen Bergin, Geraldine Healy, Michelle Lavin, John Quinn, Siobhan Glavey

Blood (2021) 138 (Supplement 1): 928.

https://doi.org/10.1182/blood-2021-146305

Published: 2021

Journal Articles

Primary Myeloma Cell Induced Von Willebrand Factor Release from the Endothelium Is Mediated By VEGF and Attenuated By Heparin

Claire Comerford, Sukhraj Pal Singh Dhami, Philip Murphy, Sean Patmore, Siobhan Glavey, John Quinn, Jamie M. O'Sullivan

Blood (2021) 138 (Supplement 1): 3141.

https://doi.org/10.1182/blood-2021-149134

Published: 2021

Journal Articles

Venetoclax and Epigenetic Modifiers: Promising Novel Combinations for the Treatment of Multiple Myeloma

Lyndsey Flanagan, Michael E. O'Dwyer, Philip Murphy, John Quinn, Siobhan Glavey, Triona Ni Chonghaile

Blood (2021) 138 (Supplement 1): 4703.

https://doi.org/10.1182/blood-2021-147185

Published: 2021

Journal Articles

Non Double-Hit Diffuse Large B Cell Lymphoma Treated with R-CHOP Has Excellent Overall Survival If Interim Scan Shows Partial or Complete Response

Philip Murphy, MD, Siobhan Glavey, MDPhD, Oscar Breathnach, MD, Philip W Murphy, Liam Grogan, MD, Patrick Morris, MD, John Quinn, MB,PhD

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-138402

Published: 2020

Journal Articles

Younger Age at Diagnosis Is Associated with an Increased Risk of Venous Thromboembolism in Multiple Myeloma

Aisling Barrett, John Quinn, MD PhD, Siobhan Glavey, MD PhD, Jeremy Sargent, FRCPath, Michelle Lavin, MB, PhD FRCPath, Patrick Thornton, MB, FRCPath, James S O'Donnell, MD PhD, Philip Murphy, MD

Blood (2018) 132 (Supplement 1): 1223.

https://doi.org/10.1182/blood-2018-99-116148

Published: 2018

Journal Articles

Founding Precision Therapy in 1q-Amplified Multiple Myeloma

Romanos Sklavenitis-Pistofidis, MD, Mairead Reidy, PhD, Daisy Huynh, MS, Karma Ziad Salem, MD, Jihye Park, PhD, Siobhan Glavey, MD PhD, Xavier Leleu, MD PhD, David Root, PhD, Irene M. Ghobrial, MD, Salomon Manier, MD PhD

Blood (2018) 132 (Supplement 1): 1007.

https://doi.org/10.1182/blood-2018-99-112673

Published: 2018

Journal Articles

Strong Correlation Between CTLA-4 and LEF1 Gene Expression Levels in CLL: Targeting of the Wnt/β-Catenin Pathway May Adversely Affect CTLA-4 Expression and Function

Philip T Murphy, MD, Gary Lynch, Stephen Bergin, John Quinn, MD PhD, Siobhan Glavey, MD, Philip W Murphy, Paul Kennedy

Blood (2016) 128 (22): 5571.

https://doi.org/10.1182/blood.V128.22.5571.5571

Published: 2016

Journal Articles

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia

Blood (2016) 127 (21): 2598–2606.

https://doi.org/10.1182/blood-2015-11-680199

Published: 2016

Includes: Supplemental data

Journal Articles

Circulating Exosomal microRNAs Are Prognostic Markers in Multiple Myeloma

Salomon Manier, MD, Herve Avet-Loiseau, Federico Campigotto, MS, Karma Salem, MD, Daisy Huynh, BS, MS, Siobhan Glavey, MD, Antonio Sacco, BS, Aldo M Roccaro, MD PhD, Stephane Minvielle, Philippe Moreau, MD PhD, Thierry Facon, Xavier Leleu, MD PhD, Edie A. Weller, PhD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 1770.

https://doi.org/10.1182/blood.V126.23.1770.1770

Published: 2015

Journal Articles

MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma

Salomon Manier, MD, John Powers, PhD, Antonio Sacco, BS, Siobhan Glavey, MD, Daisy Huynh, BS, MS, Michaela R. Reagan, PhD, Karma Salem, MD, Michele Moschetta, MD, Yuji Mishima, PhD, Xavier Leleu, MD PhD, Aldo M Roccaro, MD PhD, George Q. Daley, MD PhD, Irene M. Ghobrial, MD

Blood (2015) 126 (23): 1755.

https://doi.org/10.1182/blood.V126.23.1755.1755

Published: 2015

Journal Articles

Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix

Siobhan Glavey, MD, Alexandra Naba, PhD, Salomon Manier, MD, Manuela Gambella, Alberto Rocci, MD, Antonio Sacco, BS, John M. Asara, PhD, Michele Moschetta, MD, Michaela R. Reagan, PhD, Yuji Mishima, PhD, Yawara Kawano, MD PhD, Aldo M Roccaro, MD PhD, Antonio Palumbo, MD, Richard O. Hynes, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 2051.

https://doi.org/10.1182/blood.V124.21.2051.2051

Published: 2014

Journal Articles

Prognostic Value of Circulating Exosomal microRNAs in 112 Patients with Multiple Myeloma

Salomon Manier, MD, Herve Avet-Loiseau, Federico Campigotto, MS, Siobhan Glavey, MD, Karma Salem, MD, Daisy Huynh, MPS, Erica N Boswell, BS, Antonio Sacco, BS, Yuji Mishima, PhD, Michele Moschetta, MD, Michaela R. Reagan, PhD, Yawara Kawano, MDPhD, Kenneth C. Anderson, MD, Aldo M Roccaro, MD PhD, Philippe Moreau, MD, Thierry Facon, MD, Xavier Leleu, MD PhD, Edie A. Weller, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 2056.

https://doi.org/10.1182/blood.V124.21.2056.2056

Published: 2014

Journal Articles

Multiple Myeloma Cells Express Functional E-Selectin Ligands Which Can be Inhibited Both in-Vitro and in-Vivo Leading to Prolongation of Survival in a Murine Transplant Model

Alessandro Natoni, PhD, Michele Moschetta, MD, Siobhan Glavey, MD, Ping Wu, MBBS, MSc, Gareth J. Morgan, MD PhD, Lokesh Joshi, PhD, John L. Magnani, PhD, Irene M. Ghobrial, MD, Michael E O'Dwyer, MD FRCPI, FRCPath

Blood (2014) 124 (21): 4718.

https://doi.org/10.1182/blood.V124.21.4718.4718

Published: 2014

Journal Articles

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

Michele Moschetta, MD, Yuji Mishima, PhD, Yawara Kawano, MD PhD, Yosra Aljawai, MS, Bruno Paiva, PhD, Luis Palomera, MD, Arianna Calcinotto, Unitt L. Christine, BSc, Ilyas Sahin, MD, Antonio Sacco, BS, Siobhan Glavey, MD, Michaela R. Reagan, PhD, Salomon Manier, MD, Peter Leif Bergsagel, MD PhD, Marta Chesi, PhD, Matteo Bellone, MD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 4719.

https://doi.org/10.1182/blood.V124.21.4719.4719

Published: 2014

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Chick embryo xenograft model of multiple myeloma recapitulates immune response, systemic dissemination, and sensitivity to anti-myeloma therapeutics

JAM(A), a chromosome 1q adhesion protein, is overexpressed in 1q amplified myeloma and may represent a novel therapeutic target for high-risk disease.

Phase 1b study of cyclophosphamide, pomalidomide, dexamethasone, and daratumumab (CPD-DARA) in relapsed/refractory multiple myeloma: Safety and efficacy in a heavily pretreated population

Genomic and transcriptomic signatures of extramedullary multiple myeloma reveal possible drivers of therapeutic resistance

Acute Abdominal and Pelvic Complications in Patients with Non-Promyelocytic Acute Myeloid Leukaemia Undergoing Intensive Induction Chemotherapy Are Associated with Favorable Prognosis

Red Blood Cells from COVID-19 Patients Show Evidence of Increased Oxidative Stress and Increased Lactate Influx

Primary Myeloma Cell Induced Von Willebrand Factor Release from the Endothelium Is Mediated By VEGF and Attenuated By Heparin

Venetoclax and Epigenetic Modifiers: Promising Novel Combinations for the Treatment of Multiple Myeloma

Non Double-Hit Diffuse Large B Cell Lymphoma Treated with R-CHOP Has Excellent Overall Survival If Interim Scan Shows Partial or Complete Response

Younger Age at Diagnosis Is Associated with an Increased Risk of Venous Thromboembolism in Multiple Myeloma

Founding Precision Therapy in 1q-Amplified Multiple Myeloma

Strong Correlation Between CTLA-4 and LEF1 Gene Expression Levels in CLL: Targeting of the Wnt/β-Catenin Pathway May Adversely Affect CTLA-4 Expression and Function

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia

Circulating Exosomal microRNAs Are Prognostic Markers in Multiple Myeloma

MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma

Proteomic Characterization of the Multiple Myeloma Bone Marrow Extracellular Matrix

Prognostic Value of Circulating Exosomal microRNAs in 112 Patients with Multiple Myeloma

Multiple Myeloma Cells Express Functional E-Selectin Ligands Which Can be Inhibited Both in-Vitro and in-Vivo Leading to Prolongation of Survival in a Murine Transplant Model

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

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