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Sinto Sebastian Chirackal
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Journal Articles

Unraveling Antioxidative Metabolic Pathways in Multiple Myeloma: Augmenting IMiD Sensitivity through Intracellular Cysteine Biosynthesis Inhibition

Sinto Sebastian Chirackal, Taro Hitosugi, Gregory Ahmann, Esteban Braggio, Marta Chesi, P. Leif Bergsagel, Rafael Fonseca
Journal: Blood
Blood (2023) 142 (Supplement 1): 3291.
https://doi.org/10.1182/blood-2023-189785
Published: 2023
Journal Articles

Lenalidomide Inhibits Thioredoxin Reductase (TrxR) in Multiple Myeloma (MM) Cells but Direct Inhibition of Trxr and Thioredoxin (Trx) Can Bypass Requirement of Cereblon (CRBN)

Sinto Sebastian Chirackal, PhD, Esteban Braggio, PhD, Yuan Xiao Zhu, PhD, Chang-Xin Shi, PhD, Scott Van Wier, Gregory Ahmann, Veronica Gonzalez-Calle, MD, Marta Chesi, PhD, Leif Bergsagel, MD, Keith Stewart, M.B., Ch.B., Rafael Fonseca, MD
Journal: Blood
Blood (2016) 128 (22): 4482.
https://doi.org/10.1182/blood.V128.22.4482.4482
Published: 2016
Journal Articles

Evaluation of Revised International Staging System for Transplant-Eligible Multiple Myeloma Patients

Veronica Gonzalez-Calle, MD, Abigail Slack, Susan Luft, M.S., R.N., Kathryn Pearce, Rhett P. Ketterling, MD, Tania Jain, M.B., B.S, Sinto Sebastian Chirackal, PhD, Craig B. Reeder, MD, Joseph Mikhael, MD, Leif Bergsagel, MD, Pierre Noel, MD, Angela Mayo, P.A.-C., M.S., James L. Slack, MD, Roberta H. Adams, MD, Gregory Ahmann, Esteban Braggio, PhD, Keith Stewart, M.B., Ch.B., Scott Van Wier, Rafael Fonseca, MD
Journal: Blood
Blood (2016) 128 (22): 3452.
https://doi.org/10.1182/blood.V128.22.3452.3452
Published: 2016
Journal Articles

Immunomodulatory Drugs Inhibit H 2 O 2 Decomposition in Multiple Myeloma Cells and Its Mediated Cytotoxicity Is Determined By Cellular Antioxidative Capacity

Sinto Sebastian Chirackal, PhD, Yuan Xiao Zhu, PhD, Esteban Braggio, PhD, Chang-Xin Shi, PhD, Sonali Panchabhai, MBBS, Gregory Ahmann, BS, Scott A. Van Wier, BS, Marta Chesi, PhD, Leif Bergsagel, MD PhD, Keith Stewart, MD, Rafael Fonseca, MD
Journal: Blood
Blood (2015) 126 (23): 2475.
https://doi.org/10.1182/blood.V126.23.2475.2475
Published: 2015
Journal Articles

Ornithine Decarboxylase: Novel Prognostic Marker and Target for Multiple Myeloma Therapy

Sonali Panchabhai, MBBS, Ilana Miriam Schlam, MD, Sinto Sebastian Chirackal, PhD, Rafael Fonseca, MD
Journal: Blood
Blood (2015) 126 (23): 1824.
https://doi.org/10.1182/blood.V126.23.1824.1824
Published: 2015
Journal Articles

Role Of Folate Receptor Targeted Therapy In Multiple Myeloma

Sonali Panchabhai, MBBS, Katalin Kelemen, MD, PhD, Sinto Sebastian Chirackal, PhD, BSc, MSc, Rafael Fonseca, M.D.
Journal: Blood
Blood (2013) 122 (21): 4436.
https://doi.org/10.1182/blood.V122.21.4436.4436
Published: 2013