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Journal Articles

Glycosylation and Surface Localization Are Required for FLT3 Activation but Not for FLT3/ITD.

Allen Williams, PhD, Sina Koch, PhD, Thiede Christian, Ph.D., Patrick Brown, MD, Mark Levis, Donald Small, MD, PhD

Blood (2009) 114 (22): 2748.

https://doi.org/10.1182/blood.V114.22.2748.2748

Published: 2009

Journal Articles

Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality

Dirk Schmidt-Arras, Sylvia-Annette Böhmer, Sina Koch, Jörg P. Müller, Lutz Blei, Hauke Cornils, Reinhard Bauer, Sridhar Korasikha, Christian Thiede, Frank-D. Böhmer

Blood (2009) 113 (15): 3568–3576.

https://doi.org/10.1182/blood-2007-10-121426

Published: 2009

Includes: Supplemental data

Journal Articles

Expression and Functional Analysis of Autotaxin, a Relevant Motility and Survival Factor, in FLT3-ITD Positive Acute Myeloid Leukemia and Primary Hematopoietic Stem Cells.

Claudia Ortlepp, Christine Steudel, Sina Koch, Angela Jacobi, Satu Kyttaelae, Martin Ryser, Sebastian Brenner, Martin Bornhaeuser, Gerhard Ehninger, Christian Thiede

Blood (2008) 112 (11): 1206.

https://doi.org/10.1182/blood.V112.11.1206.1206

Published: 2008

Journal Articles

A Rapid Flow Cytometric Method for the Detection of NPM1 Mutated Patients with Acute Myeloid Leukemia (AML).

Uta Oelschlaegel, PhD, Sina Koch, PhD, Markus Schaich, MD, Frank Kroschinsky, MD, Stefani Parmentier, MD, Gerhard Ehninger, MD, Christian Thiede, MD

Blood (2008) 112 (11): 1490.

https://doi.org/10.1182/blood.V112.11.1490.1490

Published: 2008

Journal Articles

Aberrant Intracellular Retention of Mutated Receptor Tyrosine Kinase FLT3 in Human Leukemic Cells as a Potential Mechanism Supporting the Pathogenesis of Acute Myeloid Leukaemia.

Sina Koch, Martin Ryser, Angela Jacobi, Sebastian Brenner, Martin Bornhaeuser, Gerhard Ehninger, Christian Thiede

Blood (2008) 112 (11): 2245.

https://doi.org/10.1182/blood.V112.11.2245.2245

Published: 2008

Journal Articles

Interplay of CXCR4 and FLT3-ITD in the Regulation of Stem Cell Migration and Proliferation.

Angela Jacobi, Martin F. Ryser, MD, Sina Koch, Romy Lehmann, Martin Bornhaeuser, MD, PhD, Sebastian Brenner, MD

Blood (2007) 110 (11): 1818.

https://doi.org/10.1182/blood.V110.11.1818.1818

Published: 2007

Journal Articles

FLT3-ITD Mediated Growth Advantage of Human CD34+ PBPCs Is Dependent on Stromal Cells.

Angela Jacobi, Martin F. Ryser, MD, Sina Koch, Sebastian Brenner, MD

Blood (2006) 108 (11): 2546.

https://doi.org/10.1182/blood.V108.11.2546.2546

Published: 2006

Journal Articles

Differences in the Localization of Receptor Tyrosine Kinase FLT3 in Human Hematopoietic Stem and Progenitor Cells and Leukemic Blasts.

Sina Koch, Martin Ryser, MD, Martin Bornhaeuser, Gerhard Ehninger, Christian Thiede

Blood (2006) 108 (11): 1910.

https://doi.org/10.1182/blood.V108.11.1910.1910

Published: 2006

Journal Articles

High Expression of ENPP2/Autotaxin in Patients with FLT3-ITD Positive Acute Myeloid Leukemia.

Claudia Ortlepp, Christine Steudel, PhD, Sina Koch, Martin Ryser, MD, Gerhard Ehninger, Christian Thiede

Blood (2006) 108 (11): 1911.

https://doi.org/10.1182/blood.V108.11.1911.1911

Published: 2006

Journal Articles

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)

Christian Thiede, Sina Koch, Eva Creutzig, Christine Steudel, Thomas Illmer, Markus Schaich, Gerhard Ehninger, for the Deutsche Studieninitiative Leukämie (DSIL)

Blood (2006) 107 (10): 4011–4020.

https://doi.org/10.1182/blood-2005-08-3167

Published: 2006

Journal Articles

Mutations of the Nucleophosmin (NPM1) Gene Are Common in Adult Acute Myeloid Leukemia and Associated with Favorable Prognosis If Present without FLT3-ITD Mutation.

Christian Thiede, MD, Sina Koch, Eva Creutzig, Christine Steudel, PhD, Thomas Illmer, MD, Markus Schaich, MD, Gerhard Ehninger, MD

Blood (2005) 106 (11): 224.

https://doi.org/10.1182/blood.V106.11.224.224

Published: 2005

NARROW

Glycosylation and Surface Localization Are Required for FLT3 Activation but Not for FLT3/ITD.

Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality

Expression and Functional Analysis of Autotaxin, a Relevant Motility and Survival Factor, in FLT3-ITD Positive Acute Myeloid Leukemia and Primary Hematopoietic Stem Cells.

A Rapid Flow Cytometric Method for the Detection of NPM1 Mutated Patients with Acute Myeloid Leukemia (AML).

Aberrant Intracellular Retention of Mutated Receptor Tyrosine Kinase FLT3 in Human Leukemic Cells as a Potential Mechanism Supporting the Pathogenesis of Acute Myeloid Leukaemia.

Interplay of CXCR4 and FLT3-ITD in the Regulation of Stem Cell Migration and Proliferation.

FLT3-ITD Mediated Growth Advantage of Human CD34+ PBPCs Is Dependent on Stromal Cells.

Differences in the Localization of Receptor Tyrosine Kinase FLT3 in Human Hematopoietic Stem and Progenitor Cells and Leukemic Blasts.

High Expression of ENPP2/Autotaxin in Patients with FLT3-ITD Positive Acute Myeloid Leukemia.

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)

Mutations of the Nucleophosmin (NPM1) Gene Are Common in Adult Acute Myeloid Leukemia and Associated with Favorable Prognosis If Present without FLT3-ITD Mutation.

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American Society of Hematology

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American Society of Hematology

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