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Simon Francis Lacey, PhD BS
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Journal Articles

B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells (CART-BCMA) for Multiple Myeloma (MM): Initial Safety and Efficacy from a Phase I Study

Adam D. Cohen, MD, Alfred L. Garfall, MD, Edward A Stadtmauer, MD, Simon Francis Lacey, PhD BS, Eric Lancaster, MD PhD, Dan T. Vogl, MD, Karen Dengel, BSN, RN, David E Ambrose, BS, Fang Chen, PhD, Gabriela Plesa, PhD, Irina Kulikovskaya, PhD, Vanessa E Gonzalez, M.B.A, Minnal Gupta, MSc, Regina M Young, PhD, Tenesia Carey, Regina Ferthio, Brendan M. Weiss, MD, Celeste Richardson, PhD, Randi E. Isaacs, MD, J. Joseph Melenhorst, PhD, Bruce L. Levine, PhD, Carl H June, MD, Michael C. Milone, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1147.
https://doi.org/10.1182/blood.V128.22.1147.1147
Published: 2016
Journal Articles

Ruxolitinib Prevents Cytokine Release Syndrome after CART Cell Therapy without Impairing the Anti-Tumor Effect in a Xenograft Model

Saad S Kenderian, MD, Marco Ruella, MD, Olga Shestova, PhD, Miriam Y Kim, MD, Michael Klichinsky, PharmD, Fang Chen, PhD, Natalka Kengle, Simon Francis Lacey, PhD BS, J. Joseph Melenhorst, PhD, Carl H June, MD, Saar I. Gill, MD PhD
Journal: Blood
Blood (2016) 128 (22): 652.
https://doi.org/10.1182/blood.V128.22.652.652
Published: 2016
Journal Articles

Minimally Ex Vivo Manipulated Gene-Modified T Cells Display Enhanced Tumor Control

Saba Ghassemi, PhD, Patel Prachi, John Scholler, Selene Nunez-Cruz, PhD, David M. Barrett, MD PhD, Felipe Bedoya, PhD, Joseph A. Fraietta, PhD, Simon Francis Lacey, PhD BS, Bruce L Levine, PhD, Stephen A. Grupp, MD PhD, Carl H June, MD, Michael C. Milone, MD PhD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 4549.
https://doi.org/10.1182/blood.V128.22.4549.4549
Published: 2016
Journal Articles

Cars in Leukemia: Relapse with Antigen-Negative Leukemia Originating from a Single B Cell Expressing the Leukemia-Targeting CAR

Simon Francis Lacey, PhD BS, Jun Xu, PhD, Marco Ruella, MD, David M. Barrett, MD PhD, Irina Kulikovskaya, PhD, David E Ambrose, BS, Prachi R. Patel, BS, Tyler Reich, John Scholler, Farzana Nazimuddin, Joseph A. Fraietta, PhD, Shannon L Maude, MD PhD, Saar I. Gill, MD PhD, Bruce L Levine, PhD, Christopher L Nobles, PhD, Frederic D Bushman, PhD, Elena Orlando, PhD, Stephan A. Grupp, MD PhD, Carl H June, MD, Jan Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 281.
https://doi.org/10.1182/blood.V128.22.281.281
Published: 2016
Journal Articles

Treatment with Chimeric Antigen Receptor Modified T Cells Directed Against CD19 (CTL019) Results in Durable Remissions in Patients with Relapsed or Refractory Diffuse Large B Cell Lymphomas of Germinal Center and Non-Germinal Center Origin, "Double Hit" Diffuse Large B Cell Lymphomas, and Transformed Follicular to Diffuse Large B Cell Lymphomas

Stephen J. Schuster, MD, Jakub Svoboda, MD, Sunita Dwivedy Nasta, MD, Elise A. Chong, MD, Nicole Winchell, Daniel J. Landsburg, MD, David L. Porter, MD, Anthony R. Mato, MD, Honore T Strauser, April M. Schrank-Hacker, Mariusz A Wasik, MD, Simon Francis Lacey, PhD BS, Jan Joseph Melenhorst, PhD, Anne Chew, PhD, Jens Hasskarl, MD PhD, Katherine T. Marcucci, PhD, Bruce L Levine, PhD, Carl H June, MD
Journal: Blood
Blood (2016) 128 (22): 3026.
https://doi.org/10.1182/blood.V128.22.3026.3026
Published: 2016