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Journal Articles

Biochemical Engraftment and Clinical Outcomes Following Ex-Vivo Autologous Stem Cell Gene Therapy for Mucopolysaccharidosis Type IIIA

Robert F Wynn, Jane L Kinsella, Rebecca J Holley, Jane Potter, Adrian J. Thrasher, Claire Booth, Karen Buckland, Natalia Izotova, Stewart Rust, Daniel Weisberg, Heather J Church, Karen L Tylee, Kathryn L Brammeier, Helena Lee, Laura Ford, Atusa Sadegholnejat, Simon A Jones, Stuart Ellison, Brian Bigger
Journal: Blood
Blood (2022) 140 (Supplement 1): 1897–1898.
https://doi.org/10.1182/blood-2022-168672
Published: 2022
Journal Articles

Ex-Vivo Autologous Stem Cell Gene Therapy Clinical Trial for Mucopolysaccharidosis Type IIIA: Trial in Progress - NCT04201405

Jane L Kinsella, MBChB, Robert F Wynn, MRCP,MDFRCPath, Brian Bigger, PhD, Adrian J. Thrasher, MBBS, PhD FMedSci, Claire Booth, MBBS, PhD MSc, Karen Buckland, PhD, Natalia Izotova, Stewart Rust, B.Sc. (Hons), D.Clin.Psych, Pg.Dip., C.Psychol., AfBPS., Daniel Weisberg, BSc, PhD PGCert, ClinPsyD, Heather J Church, PhD, Kathryn L Brammeier, Karen L Tylee, Ceri Jones, BSc, Helena Lee, Laura Ford, Atusa Sadegholnejat, Stuart Ellison, Simon A Jones, MBChB, BSc, MRCPCH
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-141762
Published: 2020
Journal Articles

Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation: an international multicenter study

Mieke Aldenhoven, Robert F. Wynn, Paul J. Orchard, Anne O’Meara, Paul Veys, Alain Fischer, Vassili Valayannopoulos, Benedicte Neven, Attilio Rovelli, Vinod K. Prasad, Jakub Tolar, Heather Allewelt, Simon A. Jones, Rossella Parini, Marleen Renard, Victoria Bordon, Nico M. Wulffraat, Tom J. de Koning, Elsa G. Shapiro, Joanne Kurtzberg, Jaap Jan Boelens
Journal: Blood
Blood (2015) 125 (13): 2164–2172.
https://doi.org/10.1182/blood-2014-11-608075
Published: 2015
Includes: Supplemental data
Journal Articles

Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection

Stephen R. Clark, Christopher J. Guy, Martin J. Scurr, Philip R Taylor, Ann P. Kift-Morgan, Victoria J. Hammond, Christopher P. Thomas, Barbara Coles, Gareth W. Roberts, Matthias Eberl, Simon A. Jones, Nicholas Topley, Sailesh Kotecha, Valerie B. O'Donnell
Journal: Blood
Blood (2011) 117 (6): 2033–2043.
https://doi.org/10.1182/blood-2010-04-278887
Published: 2011
Includes: Supplemental data
Journal Articles

Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNγ-dependent iNOS expression in the vasculature of healthy mice

Jonathan Morton, Barbara Coles, Kate Wright, Awen Gallimore, Jason D. Morrow, Erin S. Terry, Peter B. Anning, B. Paul Morgan, Vincent Dioszeghy, Hartmut Kühn, Pavlos Chaitidis, Adrian J. Hobbs, Simon A. Jones, Valerie B. O'Donnell
Journal: Blood
Blood (2008) 111 (10): 5187–5194.
https://doi.org/10.1182/blood-2007-10-117283
Published: 2008
Journal Articles

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

Björn Rabe, Athena Chalaris, Ulrike May, Georg H. Waetzig, Dirk Seegert, Anwen S. Williams, Simon A. Jones, Stefan Rose-John, Jürgen Scheller
Journal: Blood
Blood (2008) 111 (3): 1021–1028.
https://doi.org/10.1182/blood-2007-07-102137
Published: 2008
Includes: Supplemental data
Journal Articles

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

Athena Chalaris, Björn Rabe, Krzysztof Paliga, Hans Lange, Tamas Laskay, Ceri A. Fielding, Simon A. Jones, Stefan Rose-John, Jürgen Scheller
Journal: Blood
Blood (2007) 110 (6): 1748–1755.
https://doi.org/10.1182/blood-2007-01-067918
Published: 2007
Includes: Supplemental data