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Shirin Arastu-Kapur
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Journal Articles

Inhibition Of Autophagy By ACY-1215, a Selective HDAC6 Inhibitor Accelerates Carfilzomib-Induced Cell Death In Multiple Myeloma

Yuko Mishima, Loredana Santo, Diana D. Cirstea, Homare Eda, Neeharika Nemani, Shirin Arastu-Kapur, Ph.D, Christopher J. Kirk, Ph.D, Simon S Jones, PhD, Raje Noopur, MD
Journal: Blood
Blood (2013) 122 (21): 4431.
https://doi.org/10.1182/blood.V122.21.4431.4431
Published: 2013
Journal Articles

Blocking Protein Secretion and Degradation Is a Novel Treatment Strategy For Malignant Cells With High Protein Load

Eric Lowe, Rebecca Maglathlin, Alana Lerner, Ph.D, Jack Taunton, PhD, Christopher J. Kirk, Ph.D, Shirin Arastu-Kapur, Ph.D
Journal: Blood
Blood (2013) 122 (21): 4439.
https://doi.org/10.1182/blood.V122.21.4439.4439
Published: 2013
Journal Articles

Survival Pathways Stabilized By Proteasome Inhibition Reveal PIM2 As a Novel Target For Potentiating The Anti-Myeloma Activity Of Carfilzomib

Tracey Lin, B.S., Eric Lowe, B.S., Alana Lerner, Ph.D, Christopher J. Kirk, Ph.D, Shirin Arastu-Kapur, Ph.D
Journal: Blood
Blood (2013) 122 (21): 4440.
https://doi.org/10.1182/blood.V122.21.4440.4440
Published: 2013
Journal Articles

A Novel Bruton′s Tyrosine Kinase Inhibitor CC-292 In Combination With The Proteasome Inhibitor Carfilzomib Iimpacts Multiple Myeloma Bone Microenviroment With Resultant Anti-Myeloma Activity

Homare Eda, Loredana Santo, Diana D Cirstea, Andrew J Yee, Tyler A Scullen, Neeharika Nemani, Yuko Mishima, Shirin Arastu-Kapur, Erica Evans, Juswinder Singh, Christopher J Kirk, William F Westlin, Noopur S Raje
Journal: Blood
Blood (2013) 122 (21): 682.
https://doi.org/10.1182/blood.V122.21.682.682
Published: 2013
Journal Articles

Potent Inhibition of Multiple Proteasome Subunits by Carfilzomib in Multiple Myeloma and Solid Tumor Patients

Susan J Lee, Tina M Woo, Shirin Arastu-Kapur, PhD, Alvin F Wong, Pharm.D., Thomas E Renau, PhD, Christopher J Kirk, PhD
Journal: Blood
Blood (2011) 118 (21): 5068.
https://doi.org/10.1182/blood.V118.21.5068.5068
Published: 2011
Journal Articles

Bortezomib-Resistant Cell Lines Have Increased Proteasome Levels but Remain Sensitive to Carfilzomib.

Erika Suzuki, Susan Demo, PhD, Shirin Arastu-Kapur, PhD, Christopher J Kirk, Ph.D, Mark K Bennett, PhD
Journal: Blood
Blood (2009) 114 (22): 2852.
https://doi.org/10.1182/blood.V114.22.2852.2852
Published: 2009
Journal Articles

Neurodegeneration Induced by Bortezomib Exposure in Vitro Occurs Via Proteasome Independent Mechanisms.

Shirin Arastu-Kapur, PhD, Andrew J. Ball, PhD, Janet L. Anderl, Mark K Bennett, PhD, Christopher J Kirk, Ph.D
Journal: Blood
Blood (2009) 114 (22): 2859.
https://doi.org/10.1182/blood.V114.22.2859.2859
Published: 2009
Journal Articles

Non-Proteasomal Targets of Proteasome Inhibitors Bortezomib and Carfilzomib

Shirin Arastu-Kapur, Kevin Shenk, Francesco Parlati, Mark K Bennett
Journal: Blood
Blood (2008) 112 (11): 2657.
https://doi.org/10.1182/blood.V112.11.2657.2657
Published: 2008