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Juswinder Singh
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Journal Articles

Target Engagement, Pathway Inhibition, and Efficacy Of The Bruton’s Tyrosine Kinase (Btk) Inhibitor CC-292

Daniel W Pierce, Sabine Ponader, PhD, Kumudha Balakrishnan, Varsha Gandhi, PhD, William G. Wierda, MD, Susan O'Brien, MD, Carla Heise, PhD, Mariana Nacht, PhD, Sharon Aslanian, Xiping Liu, Sean Hong, Shijuan Wu, Marianna Zavodovskaya, MS, Jeffrey Marine, Evelyn Barnett, Pilar Nava-Parada, Jay Mei, MD, Rajesh Chopra, MD, Jan A. Burger, MD, PhD, Juswinder Singh
Journal: Blood
Blood (2013) 122 (21): 4169.
https://doi.org/10.1182/blood.V122.21.4169.4169
Published: 2013
Journal Articles

A Novel Bruton′s Tyrosine Kinase Inhibitor CC-292 In Combination With The Proteasome Inhibitor Carfilzomib Iimpacts Multiple Myeloma Bone Microenviroment With Resultant Anti-Myeloma Activity

Homare Eda, Loredana Santo, Diana D Cirstea, Andrew J Yee, Tyler A Scullen, Neeharika Nemani, Yuko Mishima, Shirin Arastu-Kapur, Erica Evans, Juswinder Singh, Christopher J Kirk, William F Westlin, Noopur S Raje
Journal: Blood
Blood (2013) 122 (21): 682.
https://doi.org/10.1182/blood.V122.21.682.682
Published: 2013
Journal Articles

AVL-292, a Bruton's Tyrosine Kinase Inhibitor Impacts Bone Resorption by Abrogating Osteoclast Sealing Zone Formation in Multiple Myeloma

Homare Eda, Loredana Santo, Diana Cirstea, Andrew J. Yee, Anuj Mahindra, Tyler Scullen, Neeharika Nemani, Yuko Mishima, Erica Evans, Juswinder Singh, Wes Westlin, Noopur Raje
Journal: Blood
Blood (2012) 120 (21): 1822.
https://doi.org/10.1182/blood.V120.21.1822.1822
Published: 2012
Journal Articles

Clinical Development of AVL-292; A Potent, Selective Covalent Btk Inhibitor for the Treatment of B Cell Malignancies,

Erica Evans, PhD, Richland Tester, PhD, Sharon Aslanian, Prasoon Chaturvedi, PhD, Hormoz Mazdiyasni, Sabine Ponader, PhD, Bethany Tesar, Michael Sheets, Mariana Nacht, PhD, Kathryn Stiede, Steve Witowski, PhD, Heather Lounsbury, Russell Petter, PhD, Jennifer R. Brown, MD, PhD, Jan A. Burger, MD, PhD, Juswinder Singh, PhD, William F. Westlin, PhD
Journal: Blood
Blood (2011) 118 (21): 3485.
https://doi.org/10.1182/blood.V118.21.3485.3485
Published: 2011
Journal Articles

Targeting Bruton's Tyrosine Kinase As a Novel Approach to Inhibit Osteoclast Function in Multiple Myeloma

Homare Eda, MD, PhD, Loredana Santo, MD, Diana D. Cirstea, MD, Samantha Pozzi, MD, Miriam Canavese, PhD, Tyler A. Scullen, BA, Sonia Vallet, MD, Erica Evans, PhD, Juswinder Singh, PhD, Noopur S. Raje, MD
Journal: Blood
Blood (2011) 118 (21): 2882.
https://doi.org/10.1182/blood.V118.21.2882.2882
Published: 2011
Journal Articles

Prolonged Inhibition of BCR Signaling and Suppression of B Cell Lymphoma through Irreversible Inhibition of Bruton’s Tyrosine Kinase

Erica Evans, Michael Sheets, Hugues Bernard, Thia St. Martin, Mariana Nacht, Rich Tester, Chuck Jewell, Hormoz Mazdiyasni, Russell Petter, William Westlin, Juswinder Singh
Journal: Blood
Blood (2008) 112 (11): 2608.
https://doi.org/10.1182/blood.V112.11.2608.2608
Published: 2008