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Journal Articles

PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia

Fabienne McClanahan, Bola Hanna, Shaun Miller, Andrew James Clear, Peter Lichter, John G. Gribben, Martina Seiffert
Journal: Blood
Blood (2015) 126 (2): 203–211.
https://doi.org/10.1182/blood-2015-01-622936
Published: 2015
Includes: Supplemental data
Journal Articles

Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model

Fabienne McClanahan, John C. Riches, Shaun Miller, William P. Day, Eleni Kotsiou, Donna Neuberg, Carlo M. Croce, Melania Capasso, John G. Gribben
Journal: Blood
Blood (2015) 126 (2): 212–221.
https://doi.org/10.1182/blood-2015-02-626754
Published: 2015
Includes: Supplemental data
Journal Articles

Immune Checkpoint Blockade with Anti-PD-L1 Prevents Immune Dysfuntion and CLL Development in the TCL1 Adoptive Transfer Mouse Model

Bola Hanna, Fabienne McClanahan, MD, Andrew James Clear, BSc, Shaun Miller, Peter Lichter, PhD, Martina Seiffert, PhD, John G. Gribben, MD DSc
Journal: Blood
Blood (2014) 124 (21): 717.
https://doi.org/10.1182/blood.V124.21.717.717
Published: 2014
Journal Articles

T-Cell Dysfunction In CLL Is Mediated Not Only By PD-1/PD-L1 But Also By PD-1/PD-L2 Interactions - Partial Functionality Is Maintained In PD-1 Defined CD8 Subsets and This Can Be Further Promoted By Ibrutinib Treatment

Fabienne McClanahan, MD, Shaun Miller, John C. Riches, MD, Essam Ghazaly, MD, PhD, William P. Day, Melania Capasso, PhD, John Gribben, MD, DSc
Journal: Blood
Blood (2013) 122 (21): 4120.
https://doi.org/10.1182/blood.V122.21.4120.4120
Published: 2013