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Journal Articles

Establishing a Patient-Derived Immortalized Erythroid Progenitor Cell Model to Investigate Disease Mechanisms and Lentiviral Gene Therapy Vector in Congenital Dyserythropoietic Anemia Type II

Ravina Taak, Dinesh Babu, Manu Jamwal, Dhavapriya Palani, Prashant Sharma, Prateek Bhatia, Deepak Bansal, Shaji R Velayudhan, Reena Das

Blood (2024) 144 (Supplement 1): 1073.

https://doi.org/10.1182/blood-2024-209451

Published: 2024

Journal Articles

Factor VIII Expression from a Novel F8 Transgene through a Lentiviral Vector Transduced CD34+ Autologous Hematopoietic Stem Cells for Gene Therapy of Severe Hemophilia Α: Final Results from a Phase 1 Clinical Trial

Blood (2024) 144 (Supplement 1): 1052.

https://doi.org/10.1182/blood-2024-202882

Published: 2024

Journal Articles

Assessment of Transduction of CD34+ Human Hematopoietic Stem Cells from Patients with Severe Hemophilia-Α with Lentiviral Vector Carrying a High Expression FVIII Transgene (CD68-ET3-LV)

Gurbind Singh, Mohanashankar A M, Shaji R Velayudhan, Gabriela Denning, Abraham Sunder Singh, Anbu Jeba, Aby Abraham, Christopher B Doering, H Trent Spencer, Alok Srivastava

Blood (2023) 142 (Supplement 1): 481.

https://doi.org/10.1182/blood-2023-188513

Published: 2023

Journal Articles

Role of NF-E2 Related Factor 2 (NRF2) on Chemotherapy Resistance in Acute Myeloid Leukemia (AML) and the Effect of Pharmacological Inhibition of NRF2

Sreeja Karathedath, MSc, Bharathi M Rajamani, M.Phil, Savitha Varatharajan, MSc, Ajay Abraham, MSc, Vikram Mathews, DM, Shaji R Velayudhan, PhD, Poonkuzhali Balasubramanian, PhD

Blood (2015) 126 (23): 1272.

https://doi.org/10.1182/blood.V126.23.1272.1272

Published: 2015

Journal Articles

Identification of Erythroid Specific Enhancers By Analyzing Genome Wide Association of Transcriptional Co-Activators CBP and P300

Thiyagaraj Mayuranathan, BSc,MSc,MPhil, Janakiram Rayabaram, BSc,MSc, Aneesha Nath, BSc., MSc, Shaji R Velayudhan, PhD

Blood (2015) 126 (23): 3330.

https://doi.org/10.1182/blood.V126.23.3330.3330

Published: 2015

Journal Articles

Clinical and Molecular Characterization of Fanconi Anemia: An Indian Perspective

Nancy Beryl Janet Arthur, M.Sc, Abhijeet P Ganapule, MD, Dhavapriya Palani, B.Sc, Auro Viswabandya, MD, Vikram Mathews, MD, Aby Abraham, MD, Vivi M Srivastava, MD, Alok Srivastava, MD, Biju George, MD, Shaji R Velayudhan, PhD

Blood (2014) 124 (21): 2938.

https://doi.org/10.1182/blood.V124.21.2938.2938

Published: 2014

Journal Articles

Harnessing Gene Expression Profiling In Search Of New Candidate Genes For Ara-C Resistance In Acute Myeloid Leukemia

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Shaji R Velayudhan, Ph.D, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D

Blood (2013) 122 (21): 1299.

https://doi.org/10.1182/blood.V122.21.1299.1299

Published: 2013

Journal Articles

Expression Profiling Of Nuclear Hormone Receptors In Myeloid Leukemia Reveals Potential Novel Drug Targets For Combination Therapy

Sreeja Karathedath, M.Sc, Sukanya Ganesan, M.Sc, Wei Zhang, PhD, Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Bharathi M Rajamani, MSc, M.Phil, Shaji R Velayudhan, Ph.D, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D

Blood (2013) 122 (21): 3855.

https://doi.org/10.1182/blood.V122.21.3855.3855

Published: 2013

Journal Articles

ABC Transporter Expression in Acute Myeloid Leukemia: Association with in Vitro Cytotoxicity and Prognostic Markers

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Ashok kumar Jeyavelu, M.Sc, Shaji R Velayudhan, M.Sc, Ph.D, Rayaz Ahmed, MD, Aby Abraham, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Vikram Mathews, Poonkuzhali Balasubramanian, Ph.D

Blood (2012) 120 (21): 1438.

https://doi.org/10.1182/blood.V120.21.1438.1438

Published: 2012

Journal Articles

Carbonyl Reductase 1 Expression and Polymorphisms Influence Daunorubicin Metabolism in AML

Savitha Varatharajan, M.Sc, Ajay Abraham, M.Sc, Shaji R Velayudhan, M.Sc, Ph.D, Rayaz Ahmed, MD, Aby Abraham, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D

Blood (2011) 118 (21): 2484.

https://doi.org/10.1182/blood.V118.21.2484.2484

Published: 2011

Journal Articles

Expression of Ara-C Metabolizing Enzymes Mediates in Vitro Sensitivity to Ara-C in Primary AML Cells From Patients with Denovo AML,

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Ashok kumar Jayavelu, M.Sc, Shaji R Velayudhan, M.Sc, Ph.D, Rayaz Ahmed, MD, Aby Abraham, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, M.Sc., Ph.D

Blood (2011) 118 (21): 3481.

https://doi.org/10.1182/blood.V118.21.3481.3481

Published: 2011

Journal Articles

Population Pharmacokinetics of Cyclophosphamide in Patients with Thalassaemia Major Undergoing HSCT Shows Body Weight, CYP450, GST and ALDH Polymorphisms as Covariates Explaining Inter-Individual Variation.

Poonkuzhali Balasubramanian, Ph.D, John Carl Panetta, Ph.D, Salamun Desire, M.Sc, Shaji R Velayudhan, Ph.D, Vikram Mathews, MD, Biju George, MD, Auro Viswabandya, Mammen Chandy, MD, Alok Srivastava, MD

Blood (2009) 114 (22): 1182.

https://doi.org/10.1182/blood.V114.22.1182.1182

Published: 2009

Journal Articles

Polymorphisms in the CYP450 Genes Influences Regimen Related Toxicity and Outcome in Patients with Beta Thalassaemia Major Undergoing HSCT.

Poonkuzhali Balasubramanian, Ph.D, Salamun Desire, M.Sc, Vikram Mathews, MD, Kavitha M Lakshmi, M.Sc, Shaji R Velayudhan, Ph.D, Biju George, MD, Auro Viswabandya, MD, Mammen Chandy, MD, Alok Srivastava, MD

Blood (2009) 114 (22): 869.

https://doi.org/10.1182/blood.V114.22.869.869

Published: 2009

Journal Articles

Population Pharmacokinetics of Busulfan in Patients with Beta Thalassaemia Major Undergoing HSCT Reveals Body Weight, GSTA1 and CYP3A4 Promoter Polymorphisms as Main Covariates Explaining the Inter-Individual Variation.

Poonkuzhali Balasubramanian, Ph.D, John Carl Panetta, Ph.D, Salamun Desire, M.Sc, Shaji R Velayudhan, Ph.D, Vikram Mathews, MD, Biju George, MD, Auro Viswabandya, MD, Mammen Chandy, MD, Alok Srivastava, MD

Blood (2009) 114 (22): 3349.

https://doi.org/10.1182/blood.V114.22.3349.3349

Published: 2009

Journal Articles

Fluorescent PCR Based Gene Dose Assessment for Detection of Deletion Mutations in the FIX Gene Among Carriers of Hemophilia B.

Eunice Sindhuvi Edison, Ph.D, G. Sankari Devi, B.Sc, G. Jayandharan, Ph.D, Shaji R Velayudhan, Ph.D, Auro Viswabandya, MD, Vikram Mathews, MD, Mammen Chandy, MD, Alok Srivastava, MD

Blood (2009) 114 (22): 3486.

https://doi.org/10.1182/blood.V114.22.3486.3486

Published: 2009

Journal Articles

Increased ABCG2 Expression Could Be Responsible for Resistance to Imatinib Mesylate in Patients with Chronic Myeloid Leukemia Who Do Not Have Mutations in BCR-ABL Kinase Domain

Poonkuzhali Balasubramanian, Preetha Markose, Ezhilarasi Chendamarai, Vikram Mathews, MD, Vivi Srivastava, Shaji R Velayudhan, Kavitha M Lakshmi, Auro Viswabandhya, Biju George, Alok Srivastava, Mammen Chandy

Blood (2008) 112 (11): 5026.

https://doi.org/10.1182/blood.V112.11.5026.5026

Published: 2008

NARROW

Establishing a Patient-Derived Immortalized Erythroid Progenitor Cell Model to Investigate Disease Mechanisms and Lentiviral Gene Therapy Vector in Congenital Dyserythropoietic Anemia Type II

Factor VIII Expression from a Novel F8 Transgene through a Lentiviral Vector Transduced CD34+ Autologous Hematopoietic Stem Cells for Gene Therapy of Severe Hemophilia Α: Final Results from a Phase 1 Clinical Trial

Assessment of Transduction of CD34+ Human Hematopoietic Stem Cells from Patients with Severe Hemophilia-Α with Lentiviral Vector Carrying a High Expression FVIII Transgene (CD68-ET3-LV)

Role of NF-E2 Related Factor 2 (NRF2) on Chemotherapy Resistance in Acute Myeloid Leukemia (AML) and the Effect of Pharmacological Inhibition of NRF2

Identification of Erythroid Specific Enhancers By Analyzing Genome Wide Association of Transcriptional Co-Activators CBP and P300

Clinical and Molecular Characterization of Fanconi Anemia: An Indian Perspective

Harnessing Gene Expression Profiling In Search Of New Candidate Genes For Ara-C Resistance In Acute Myeloid Leukemia

Expression Profiling Of Nuclear Hormone Receptors In Myeloid Leukemia Reveals Potential Novel Drug Targets For Combination Therapy

ABC Transporter Expression in Acute Myeloid Leukemia: Association with in Vitro Cytotoxicity and Prognostic Markers

Carbonyl Reductase 1 Expression and Polymorphisms Influence Daunorubicin Metabolism in AML

Expression of Ara-C Metabolizing Enzymes Mediates in Vitro Sensitivity to Ara-C in Primary AML Cells From Patients with Denovo AML,

Population Pharmacokinetics of Cyclophosphamide in Patients with Thalassaemia Major Undergoing HSCT Shows Body Weight, CYP450, GST and ALDH Polymorphisms as Covariates Explaining Inter-Individual Variation.

Polymorphisms in the CYP450 Genes Influences Regimen Related Toxicity and Outcome in Patients with Beta Thalassaemia Major Undergoing HSCT.

Population Pharmacokinetics of Busulfan in Patients with Beta Thalassaemia Major Undergoing HSCT Reveals Body Weight, GSTA1 and CYP3A4 Promoter Polymorphisms as Main Covariates Explaining the Inter-Individual Variation.

Fluorescent PCR Based Gene Dose Assessment for Detection of Deletion Mutations in the FIX Gene Among Carriers of Hemophilia B.

Increased ABCG2 Expression Could Be Responsible for Resistance to Imatinib Mesylate in Patients with Chronic Myeloid Leukemia Who Do Not Have Mutations in BCR-ABL Kinase Domain

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American Society of Hematology

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American Society of Hematology

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