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Sankaranarayanan Kannan
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Journal Articles

A Novel DLL1-Anti-CD19 Chimeric Protein Effectively Targets Notch Activation to B-Cell Acute Lymphoblastic Leukemia and Induces Cell Death

Rebecca E Wiersma, Sankaranarayanan Kannan, PhD, Srinivas S. Somanchi, PhD, Lizhi Zeng, Patrick A. Zweidler-McKay, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4833.
https://doi.org/10.1182/blood.V126.23.4833.4833
Published: 2015
Journal Articles

A Novel Notch/NRF2 Mechanism Mediates Reductive Stress in Acute Myeloblastic Leukemia (AML): A Therapeutic Strategy to Overcome Chemoresistance

Sankaranarayanan Kannan, PhD, Patrick A. Zweidler-McKay, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4834.
https://doi.org/10.1182/blood.V126.23.4834.4834
Published: 2015
Journal Articles

Notch Signaling In B-ALL Reveals PLK1 As A Potential Therapeutic Target In B-ALL: PLK1-Selective Inhibitor Poloxin Modulates Cyclin B and P53 Pathways, Leading To Growth Arrest and Apoptosis

Sankaranarayanan Kannan, PhD, Mandy A Hall, PhD, Leonard S Golfman, PhD, Patrick A Zweidler-McKay, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2912.
https://doi.org/10.1182/blood.V122.21.2912.2912
Published: 2013
Journal Articles

Notch/HES1 Signaling Stabilizes p53 Expression Via a Novel PARP1-Chfr-PLK1-Mediated Mechanism in B-ALL

Sankaranarayanan Kannan, PhD, Patrick A Zweidler-McKay, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1292.
https://doi.org/10.1182/blood.V120.21.1292.1292
Published: 2012
Journal Articles

Notch/HES1 Implicated As a Tumor Suppressor Mechanism in Human AML in Vivo

Leonard S Golfman, PhD, Sankaranarayanan Kannan, PhD, Mandy A Hall, PhD, Patrick A Zweidler-McKay, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3524.
https://doi.org/10.1182/blood.V120.21.3524.3524
Published: 2012
Journal Articles

Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression

Sankaranarayanan Kannan, Wendy Fang, Guangchun Song, Charles G. Mullighan, Richard Hammitt, John McMurray, Patrick A. Zweidler-McKay
Journal: Blood
Blood (2011) 117 (10): 2891–2900.
https://doi.org/10.1182/blood-2009-12-253419
Published: 2011
Includes: Supplemental data
Journal Articles

Multiple Mechanisms of Notch-Mediated B-ALL Growth Arrest Via HES1 and PLK1: KIF11, CyclinB and p53

Sankaranarayanan Kannan, PhD, Wendy Fang, MD, Patrick Zweidler-McKay, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3137.
https://doi.org/10.1182/blood.V116.21.3137.3137
Published: 2010
Journal Articles

Cell Specific Consequences of Notch Signaling: PARP1/HES1 Interaction Reveals a Novel Tumor Suppressor Mechanism.

Sankaranarayanan Kannan, PhD, Patrick A. Zweidler-McKay, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2388.
https://doi.org/10.1182/blood.V114.22.2388.2388
Published: 2009
Journal Articles

Understanding the Role of TRKA Receptor in Acute Myeloid Leukemias: From Proliferation and Pro-Survival Signals to a Novel Therapeutic Approach

Maurizio L Ghisoli, MD, Wendy Fang, MD, Timothy C Graham, BS, Alejandro G Levy, MD, Lizhi Zeng, MD, Sankaranarayanan Kannan, PhD, Riitta M Nolo, PhD, Christine Pien, PhD, Jeffrey L Brown, PhD, Patrick A Zweidler-McKay, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3789.
https://doi.org/10.1182/blood.V112.11.3789.3789
Published: 2008