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Ryan MacKenzie
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Journal Articles

Functional RNAi Screen Identifies Novel Cytokine and Growth Factor Receptors Critical for Leukemia Cell Growth

Anupriya Agarwal, PhD, Ryan MacKenzie, BS, Rita M. Braziel, MD, Jeffrey W Tyner, Brian J. Druker
Journal: Blood
Blood (2012) 120 (21): 1308.
https://doi.org/10.1182/blood.V120.21.1308.1308
Published: 2012
Journal Articles

Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML

Anupriya Agarwal, Angela G. Fleischman, Curtis L. Petersen, Ryan MacKenzie, Samuel Luty, Marc Loriaux, Brian J. Druker, Randall L. Woltjer, Michael W. Deininger
Journal: Blood
Blood (2012) 120 (13): 2658–2668.
https://doi.org/10.1182/blood-2011-05-355396
Published: 2012
Journal Articles

A Novel SET Antagonist (OP449) Is Cytotoxic to CML Cells, Including the Highly-Resistant BCR-ABL T315I Mutant, and Demonstrates Enhanced Efficacy in Combination with ABL Tyrosine Kinase Inhibitors,

Anupriya Agarwal, PhD, Ryan MacKenzie, BS, Jessica Oddo, B.S., Michael P Vitek, PhD, Dale J. Christensen, PhD, Brian J. Druker
Journal: Blood
Blood (2011) 118 (21): 3757.
https://doi.org/10.1182/blood.V118.21.3757.3757
Published: 2011
Journal Articles

Cryptic Intracellular Retention of ABL Tyrosine Kinase Inhibitors within CML Cells Mediates Apoptosis Commitment Following Acute Drug Exposure,

Thomas O'Hare, Christopher A. Eide, Lauren T. Adrian, Anupriya Agarwal, PhD, Matthew S. Zabriskie, Ryan MacKenzie, BS, Dorian H. LaTocha, BS, Huihong You, PhD, Jenny Luo, BS, Steven M. Riddle, PhD, Bryan Marks, PhD, Dennis R. Koop, PhD, John Apgar, PhD, Michael W. Deininger, Brian J. Druker
Journal: Blood
Blood (2011) 118 (21): 3504.
https://doi.org/10.1182/blood.V118.21.3504.3504
Published: 2011
Journal Articles

JAK2-Mediated Extrinsic Survival of CML Stem Cells: Exploring the Potential Combination of BCR-ABL and JAK2 Inhibitors In Vivo

Elie Traer, MD, PhD, Ryan MacKenzie, Jennifer Snead, PhD, Brian J Druker, MD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 199.
https://doi.org/10.1182/blood.V116.21.199.199
Published: 2010
Journal Articles

Defining Extrinsic Survival Pathways in CML Progenitor Cells.

Ryan Mackenzie, Jennifer Snead, PhD, Jonathan VanDyke, Michael Deininger, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 941.
https://doi.org/10.1182/blood.V114.22.941.941
Published: 2009
Journal Articles

The Oncogenic Role of Tumor Suppressor Protein p27 in Ph+ Chronic Myeloid Leukemia.

Anupriya Agarwal, PhD, Ryan Mackenzie, Dorian LaTocha, Kavin Vasudevan, Eduardo Firpo, Marc Loriaux, Keiichi Nakayama, Brian J. Druker, MD, James M Roberts, Michael Deininger, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3276.
https://doi.org/10.1182/blood.V114.22.3276.3276
Published: 2009