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Development of a Neural Network to Predict Thrombosis in the Antiphospholipid Syndrome with an Accuracy of 87%

Romy Kremers, PhD, Stéphane Zuily, MD PhD, Philip De Groot, PhD, Coenraad Hemker, MD PhD, Denis Wahl, MD PhD, Bas De Laat, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3796.
https://doi.org/10.1182/blood-2018-99-115834
Published: 2018
Journal Articles

Applying Neural Networking Identifies Antiphospholipid Syndrome Patients with an Accuracy of 98.7%

Romy Kremers, PhD, Stéphane Zuily, MDPhD, Hilde Kelchtermans, PhD, Philip G. de Groot, PhD, Tessa Peters, Saartje Bloemen, PhD, Coenraad Hemker, MD PhD, Denis Wahl, MD PhD, Bas De Laat, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 460.
https://doi.org/10.1182/blood.V130.Suppl_1.460.460
Published: 2017
Journal Articles

Fixed Doses of Anticoagulants Cause Wide Variation of Thrombin Generation

Coenraad Hemker, MD PhD, Saartje Bloemen, PhD, Romy Kremers, PhD, Hilde Kelchtermans, PhD, Bas De Laat, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5012.
https://doi.org/10.1182/blood.V128.22.5012.5012
Published: 2016
Journal Articles

The Rate of Prothrombin Conversion Is Increased in Antiphospholipid Syndrome and Is Insensitive to Thrombomodulin

Romy Kremers, PhD, Stéphane Zuily, MD MPH, PhD, Hilde Kelchtermans, PhD, Tessa Peters, Saartje Bloemen, PhD, Véronique Regnault, PhD, Denis Wahl, MD MPH, PhD, Bas De Laat, MD PhD
Journal: Blood
Blood (2016) 128 (22): 718.
https://doi.org/10.1182/blood.V128.22.718.718
Published: 2016
Journal Articles

Elevated Fibrinogen Levels in Patients Treated with Vitamin K Antagonists Attenuate the Inactivation of Thrombin

Romy Kremers, PhD, Saartje Bloemen, PhD, Hilde Kelchtermans, PhD, Tessa Peters, Rob Wagenvoord, PhD, Bas De Laat, MD PhD, Coenraad Hemker, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3837.
https://doi.org/10.1182/blood.V128.22.3837.3837
Published: 2016
Journal Articles

Restoration of Procoagulant Factor Levels after Cardiac Surgery Causes Thrombin Generation to Rise to Thrombotic Levels

Romy Kremers, MSc, Yvonne Bosch, MSc, Saartje Bloemen, PhD, Bas De Laat, MD PhD, Rob Wagenvoord, PhD, Raed Al Dieri, PhDPharmD, Coenraad Hemker, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1143.
https://doi.org/10.1182/blood.V126.23.1143.1143
Published: 2015
Journal Articles

Rebalanced Thrombin Generation in Liver Cirrhosis Calls for Tailored Transfusion Protocols

Romy Kremers, MSc, Marie-Claire Kleinegris, MD, Hugo ten Cate, MD PhD, Bas De Laat, MD PhD, Rob Wagenvoord, PhD, Coenraad Hemker, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3523.
https://doi.org/10.1182/blood.V126.23.3523.3523
Published: 2015
Journal Articles

Alpha-2-Macroglobulin Is a Major Determinant Of a Lower Thrombin Generation In Infants and Children Compared To Adults

Romy Kremers, Saartje Bloemen, Raed Al Dieri, PhD, Coen H Hemker, Vasiliki Karlaftis, Chantal Attard, Bas de Laat, PhD, Paul Monagle, MBBS, MD, MSc, Vera Ignjatovic, PhD
Journal: Blood
Blood (2013) 122 (21): 2344.
https://doi.org/10.1182/blood.V122.21.2344.2344
Published: 2013
Journal Articles

Fibrinogen Attentuates Thrombin Decay In a Concentration-Dependent Manner

Romy Kremers, Rob Wagenvoord, PhD, Coenraad Hemker, PhD
Journal: Blood
Blood (2013) 122 (21): 2346.
https://doi.org/10.1182/blood.V122.21.2346.2346
Published: 2013
Journal Articles

α2Macroglobulin Fails To Compensate For Decreased Thrombin Decay In Severe Antithrombin Deficiency In Liver Cirrhosis Patients

Romy Kremers, Marie-Claire Kleinegris, Bas De Laat, PhD, Rob Wagenvoord, PhD, Coenraad Hemker, PhD
Journal: Blood
Blood (2013) 122 (21): 3576.
https://doi.org/10.1182/blood.V122.21.3576.3576
Published: 2013