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Journal Articles

Prognostic and Predictive Impact of Small PNH Clones in a Large Cohort of Patients with Myelodysplastic Syndromes and Aplastic Anemia: A Single-Center Experience

Bruno Fattizzo, MD, Alan Dunlop, Robin M. Ireland, FRCP, Shireen Kassam, MD, Dario Consonni, MD, Deborah Yallop, MBBS FRCP FRCPath PhD, Ghulam J. Mufti, Judith Marsh, Alberto Zanella, MD, Wilma Barcellini, MD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath

Blood (2018) 132 (Supplement 1): 3870.

https://doi.org/10.1182/blood-2018-99-116772

Published: 2018

Journal Articles

Clinical Intervention Using NGS-Based Kinase Domain Mutation Testing in CML Patients

Aytug Kizilors, PhD, Patrick Harrington, FRCPath, MRCP, Sophie Jackson, BSc, Nicholas Lea, PhD, Joel Newman, MBBS, MRCP, BSc, FRCPath, Richard Gale, FRCPath, FRCP, Sandra Hassan, MD, Evangelia Dimitriadou, MD, Elena Crisà, MD, Luke Ficinski, BSc, Isabel Sa, BSc, Anita Arasaretnam, MD, Vijayavalli Dhanapal, MD, Timothy Corbett, FRCP, FRCPath, Robin M. Ireland, FRCP, Antonio Pagliuca, Ghulam J. Mufti, Hugues De Lavallade

Blood (2018) 132 (Supplement 1): 3025.

https://doi.org/10.1182/blood-2018-99-118905

Published: 2018

Journal Articles

Low-Dose Second Generation TKI Is an Effective Approach to Reduce TKI Related Side Effects and Toxicity While Preserving Molecular Response in CML Patients with TKI Intolerance

Varun Mehra, MRCP, FRCPath, Titilola Oyebamiji, Stefanie Widya, Robin M. Ireland, FRCP, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Kavita Raj, MD PhD, Donal McLornan, Judith Marsh, MD, Victoria Potter, Joanna Large, Isabel Duggins, Aytug Kizilors, PhD, Nicholas Lea, PhD, Antonio Pagliuca, MD, Ghulam Mufti, DM, FRCP, FRCPath, Hugues De Lavallade

Blood (2017) 130 (Supplement 1): 5250.

https://doi.org/10.1182/blood.V130.Suppl_1.5250.5250

Published: 2017

Journal Articles

Hypoplastic Myelodysplastic Syndrome: Clinical, Histopathological and Molecular Characterization

ELISA Bono, MD, Donal McLornan, Erica Travaglino, Shreyans Gandhi, MBBS,MDMNAMS, Anna Gallì, Alesia Abigael Khan, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Emanuela Boveri, Kavita Raj, Chiara Elena, Robin M. Ireland, FRCP, Antonio Bianchessi, Jie Jiang, Gabriele Todisco, Luca Malcovati, MD, Judith Marsh, MD, Mario Cazzola, MD, Ghulam Mufti, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 588.

https://doi.org/10.1182/blood.V130.Suppl_1.588.588

Published: 2017

Journal Articles

Targeted Sequencing of 647 Patients with Myeloid Malignancies, Marrow Failures and Cytopenia: A Prospective Analysis

Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Steven Best, PhD, Aytug Kizilors, PhD, Shreyans Gandhi, MD DNB, MRCP, FRCPath, Victoria T Potter, Judith C. W. Marsh, MD FRCP, FRCPath, Nicholas Lea, PhD, Robin M. Ireland, FRCP, FRCPath, Ghulam J Mufti, MD

Blood (2016) 128 (22): 1981.

https://doi.org/10.1182/blood.V128.22.1981.1981

Published: 2016

Journal Articles

P53 Protein Expression Correlates with Adverse Outcome in Low-Risk Myelodysplastic Syndromes

Francesca Donatelli, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Alexander e Smith, PhD, Jon Salisbury, Syed A Mian, BSc, M.Phil, Robin M. Ireland, FRCP, FRCPath, Abu Arqoub Hadil, Victoria T Potter, Ghulam J. Mufti, MD PhD

Blood (2016) 128 (22): 5505.

https://doi.org/10.1182/blood.V128.22.5505.5505

Published: 2016

Journal Articles

Impact of Finding of Low Level Kinase Domain Mutations Using Ultra Deep Next Generation Sequencing in Patients with Chronic Phase CML

Aytug Kizilors, PhD, Elena Crisa, MD, Nicholas Lea, PhD, Steven Best, PhD, Mian Syed, PhD, Robin M. Ireland, FRCP, FRCPath, Maadh Aldouri, FRCPath, Christopher Pocock, Timothy Corbett, FRCP, FRCPath, Emily Elizabeth Bart-Smith, MRCP,BSc, Richard Gale, FRCPath, FRCP, Clare Wykes, FRCPath, FRCP, Simon Weston-Smith, FRCP, FRCPath, Donal McLornan, MDPhD, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD PhD, Hugues de Lavallade, MD PhD

Blood (2015) 126 (23): 347.

https://doi.org/10.1182/blood.V126.23.347.347

Published: 2015

Journal Articles

HCT-CI Is Not a Useful Predictor for Non Relapse Mortality in Older Patients (>60 years old) Receiving RIC Transplant for AML or MDS

Victor Noriega, MD, Hugues de Lavallade, MD, Victoria T Potter, MBBS, FRCPA, FRACP, Pramila Krishnamurthy, Judith C. W. Marsh, Prof MD PhD, Stephen Devereux, FRCP, FRCPath, Ph.D., Robert E. Marcus, MBBS, FRCP, FRCPath, Kavita Raj, Donal McLornan, MD, PhD, Anjum Bashir Khan, MBChB, MRCP, Sangeeta Atwal, MBBS MRCP FRCPath, Robin M. Ireland, FRCP, FRCPath, Deborah Yallop, BSc, FRCPath, MB, BS, MRCP, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J Mufti, FRCP, FRCPath, M.D.

Blood (2012) 120 (21): 4158.

https://doi.org/10.1182/blood.V120.21.4158.4158

Published: 2012

Journal Articles

Adverse Effect of Very Poor Cytogenetics and Monosomal Karyotype On Outcomes Following T-Deplete Reduced Intensity Conditioned Stem Cell Transplant for MDS and AML.

Pramila Krishnamurthy, MA MRCP FRCPath, Victoria T Potter, MBBS, FRCPA, FRACP, Austin G Kulasekararaj, Victor Noriega, Hugues de Lavallade, Robin M. Ireland, FRCP, FRCPath, Stephen Devereux, FRCP, FRCPath, Judith C. W. Marsh, MD, PhD, Robert E. Marcus, MBBS, FRCP, FRCPath, Barbara Czepulkowski, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD

Blood (2012) 120 (21): 3141.

https://doi.org/10.1182/blood.V120.21.3141.3141

Published: 2012

Journal Articles

Long-Term Outcomes of Reduced Intensity Conditioning Haematopoietic Stem Cell Transplantation (RIC-HSCT) for AML with Myelodysplasia-Related Changes

Victoria T Potter, MBBS, FRCPA, FRACP, Pramila Krishnamurthy, ZiYi Lim, Victoria J Tindell, MBChB FRCPath, Stephen Devereux, FRCP, FRCPath, PhD, Robert E. Marcus, MBBS, FRCP, FRCPath, Robin M. Ireland, FRCP, FRCPath, Judith C. W. Marsh, Prof MD PhD, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 3079.

https://doi.org/10.1182/blood.V118.21.3079.3079

Published: 2011

Journal Articles

TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis

Austin G Kulasekararaj, Alexander E Smith, PhD, Syed A Mian, Pramila Krishnamurthy, Azim M Mohamedali, PhD, Nicholas C Lea, PhD, Janet Hayden, Joop Gaken, Modupe Elebute, Robin M. Ireland, FRCP, FRCPath, Sabine Pomplun, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 792.

https://doi.org/10.1182/blood.V118.21.792.792

Published: 2011

Journal Articles

Pre-Emptive Donor Lymphocyte Infusions (DLI) Lead to High Cure Rates in T-Cell Depleted Allogeneic Haemopoietic Stem Cell Transplants for MDS/AML

Pramila Krishnamurthy, Victoria T Potter, MBBS, FRCPA, FRACP, ZiYi Lim, Austin G Kulasekararaj, Aloysius Y Ho, Judith C. W. Marsh, Prof MD PhD, Robin M. Ireland, FRCP, FRCPath, Stephen Devereux, FRCP, FRCPath, PhD, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 660.

https://doi.org/10.1182/blood.V118.21.660.660

Published: 2011

Journal Articles

Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency,

Jie Jiang, PhD, Austin G Kulasekararaj, Pramila Krishnamurthy, Alexander E Smith, PhD, Syed A Mian, Shreyans Gandhi, Janet Hayden, Joop Gaken, Modupe Elebute, Robin M. Ireland, FRCP, FRCPath, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 3826.

https://doi.org/10.1182/blood.V118.21.3826.3826

Published: 2011

Journal Articles

Polycomb Complex Group Gene Mutations and Their Prognostic Relevance In 5-Azacitidine Treated Myelodysplastic Syndrome Patients

Blood (2010) 116 (21): 125.

https://doi.org/10.1182/blood.V116.21.125.125

Published: 2010

Journal Articles

Recurrent Novel Regions of Uniparental Disomy and Homozygous Deletions in Mycosis Fungoides Identified Using High Resolution Single Nucleotide Polymorphism Analysis.

Azim M Mohamedali, PhD, Tracey J Mitchell, PhD, Silvia Ferreira, PhD, Barbara A Guinn, PhD, Robin M. Ireland, FRCP, FRCPath, Sean J Whittaker, MD, FRCP, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath

Blood (2009) 114 (22): 2644.

https://doi.org/10.1182/blood.V114.22.2644.2644

Published: 2009

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Prognostic and Predictive Impact of Small PNH Clones in a Large Cohort of Patients with Myelodysplastic Syndromes and Aplastic Anemia: A Single-Center Experience

Clinical Intervention Using NGS-Based Kinase Domain Mutation Testing in CML Patients

Low-Dose Second Generation TKI Is an Effective Approach to Reduce TKI Related Side Effects and Toxicity While Preserving Molecular Response in CML Patients with TKI Intolerance

Hypoplastic Myelodysplastic Syndrome: Clinical, Histopathological and Molecular Characterization

Targeted Sequencing of 647 Patients with Myeloid Malignancies, Marrow Failures and Cytopenia: A Prospective Analysis

P53 Protein Expression Correlates with Adverse Outcome in Low-Risk Myelodysplastic Syndromes

Impact of Finding of Low Level Kinase Domain Mutations Using Ultra Deep Next Generation Sequencing in Patients with Chronic Phase CML

HCT-CI Is Not a Useful Predictor for Non Relapse Mortality in Older Patients (>60 years old) Receiving RIC Transplant for AML or MDS

Adverse Effect of Very Poor Cytogenetics and Monosomal Karyotype On Outcomes Following T-Deplete Reduced Intensity Conditioned Stem Cell Transplant for MDS and AML.

Long-Term Outcomes of Reduced Intensity Conditioning Haematopoietic Stem Cell Transplantation (RIC-HSCT) for AML with Myelodysplasia-Related Changes

TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis

Pre-Emptive Donor Lymphocyte Infusions (DLI) Lead to High Cure Rates in T-Cell Depleted Allogeneic Haemopoietic Stem Cell Transplants for MDS/AML

Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency,

Polycomb Complex Group Gene Mutations and Their Prognostic Relevance In 5-Azacitidine Treated Myelodysplastic Syndrome Patients

Recurrent Novel Regions of Uniparental Disomy and Homozygous Deletions in Mycosis Fungoides Identified Using High Resolution Single Nucleotide Polymorphism Analysis.

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