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Journal Articles

High-Efficiency Lentiviral Genetic Modification of Primary Human Natural Killer Cells

Giacomo Waller, BS, David Allan, Dhana Chinnasamy, MSc, PhD, Mala Chakraborty, PhD, Emily Levy, MS, Michael Hochman, MD, Long Chen, MD PhD, Akkapon Poolcharoen, Georg Aue, Kate Stringaris, MD PhD, Robert Reger, MS, Richard Childs, MD

Blood (2017) 130 (Supplement 1): 5566.

https://doi.org/10.1182/blood.V130.Suppl_1.5566.5566

Published: 2017

Journal Articles

Durable Remission of Refractory and Advanced Stage Mycosis Fungoides/Sezary Syndrome (MF/SS) Utilizing an "Outpatient" Alemtuzumab and Fludarabine-Based Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation (PBSCT)

Phuong Vo, Ramaprasad Srinivasan, Enkhtsetseg Purev, MD PhD, Emily McDuffee, Lisa Cook, Tatyana Worthy, Geri Hawks, Prince Patricia, Reem Shalabi, Brian Wells, Robert Reger, MS, Hanh Khuu, David Stroncek, Xin Tian, PhD, Nancy Geller, Georg Aue, Richard Childs, MD

Blood (2017) 130 (Supplement 1): 1962.

https://doi.org/10.1182/blood.V130.Suppl_1.1962.1962

Published: 2017

Journal Articles

Final Result of a Pilot Study Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Allo-Immunized Patients Receiving HLA Mismatched Platelets

Phuong Vo, Enkhtsetseg Purev, MD PhD, Kamille West, Emily McDuffee, Tatyana Worthy, Lisa Cook, Geri Hawks, Brian Wells, Reem Shalabi, Patricia Prince, Tom Hughes, Willy Fleigel, Sharon Adams, MT, CHS (ABHI), Robert Reger, MS, Xin Tian, PhD, Georg Aue, Richard Childs, MD

Blood (2017) 130 (Supplement 1): 1119.

https://doi.org/10.1182/blood.V130.Suppl_1.1119.1119

Published: 2017

Journal Articles

A Novel Method to Study the in Vivo Trafficking and Homing of Adoptively Transferred NK Cells in Rhesus Macaques and Humans

Jan Davidson-Moncada, MD PhD MSc, Noriko Sato, MD PhD, Robert F Hoyt, DVM, Robert N Reger, Marvin Thomas, DVM, MS, Randy Clevenger, Mark E. Metzger, Robert E. Donahue, Philip C Eclarinal, BS, CNMT, Lawrence Szajek, Gary L Griffiths, PhD, Cynthia E. Dunbar, MD, Peter Choyke, MD, Richard Childs, MD

Blood (2014) 124 (21): 659.

https://doi.org/10.1182/blood.V124.21.659.659

Published: 2014

Journal Articles

Clinical-Grade mRNA Electroporation of NK Cells: A Novel and Highly Efficient Method to Genetically Reprogram Human NK Cells for Cancer Immunotherapy

Mattias Carlsten, MD PhD, Linhong Li, Su Su, MD PhD, Maria Berg, Robert Reger, Madhusudan V. Peshwa, Richard Childs, MD

Blood (2014) 124 (21): 2153.

https://doi.org/10.1182/blood.V124.21.2153.2153

Published: 2014

Journal Articles

Forced Fucosylation With ASC-101 Enhances The Binding Of Ex Vivo Expanded Human NK Cells To E-Selectin: A Novel Method To Improve The Homing Of Adoptively Transferred NK Cells To The Bone Marrow In Patients With Hematological Malignancies

Toshihiro Onishi, MD, Maria Berg, Robert Reger, Leonard Miller, PhD, Steve Wolpe, Lynnet Koh, MS, MBA, Richard Childs, MD

Blood (2013) 122 (21): 4499.

https://doi.org/10.1182/blood.V122.21.4499.4499

Published: 2013

Journal Articles

The Unique Ontogeny Of Natural Killer Cells As Revealed By Genetic Barcoding In The Nonhuman Primate Model

Chuanfeng Wu, PhD, Jan K. Davidson-Moncada, MD, PhD, Rong Lu, PhD, Brian Li, Allen E. Krouse, Mark E. Metzger, Robert E. Donahue, Irving L. Weissman, MD, Richard Childs, MD, Cynthia E. Dunbar, MD

Blood (2013) 122 (21): 15.

https://doi.org/10.1182/blood.V122.21.15.15

Published: 2013

Journal Articles

Rhesus Macaque NK Cells Expanded Ex Vivo Undergo Similar Phenotypic and Functional Changes Observed With Expanded Human NK Cells Providing An Excellent Model To Optimize Adoptive NK Cell Transfer

Jan K. Davidson-Moncada, MD, PhD, Richard Childs, MD, Cynthia E. Dunbar, MD, Robert Reger, Ritesh Kotecha, Maria Berg, Chuanfeng Wu, PhD

Blood (2013) 122 (21): 2028.

https://doi.org/10.1182/blood.V122.21.2028.2028

Published: 2013

Journal Articles

Optimization of an Intra-Bone Hematopoietic Stem Cell Delivery Technique in a Swine Model.

Jeremy M Pantin, MB.BS., Robert F Hoyt, Jr., DVM, Omer Aras, MD, Marcus Y Chen, MD, Noriko Sato, MD, PhD, Peter Choyke, MD, Richard Childs, MD

Blood (2012) 120 (21): 2990.

https://doi.org/10.1182/blood.V120.21.2990.2990

Published: 2012

Journal Articles

Nicotinamide (NAM) Increases Surface Expression of CD62L On in Vitro Expanded NK Cells

Ewelina K. Mamcarz, MD, Maria Berg, Tony Peled, Gabi M Frei, Robert Reger, Xin Tian, Ph.D., Richard Childs, MD

Blood (2012) 120 (21): 4355.

https://doi.org/10.1182/blood.V120.21.4355.4355

Published: 2012

Journal Articles

High Dose Plerixafor Is Safe and Mobilizes Higher Numbers of CD34+ Cells Compared with Standard Dose Plerixafor

Jeremy M Pantin, MB.BS., Xin Tian, Ph.D., Matthew M. Hsieh, MD, Lisa Cook, RN, BSN, Theresa Donohue, MHS, PA-C, Elena Cho, RN MSN, Aleah Smith, Robert Reger, Thomas Trischman, PhD, Hanh Khuu, MD, Richard Childs, MD

Blood (2012) 120 (21): 585.

https://doi.org/10.1182/blood.V120.21.585.585

Published: 2012

Journal Articles

Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

Phillip Scheinberg, MD, Danielle M. Townsley, MD, MSc, Bogdan Dumitriu, MD, Olga Rios, RN, Barbara Weinstein, RN, Minoo Battiwalla, MD, MS, Richard Childs, MD, Cynthia E. Dunbar, MD, A. John Barrett, MD, Colin O. Wu, Neal S. Young, MD

Blood (2012) 120 (21): 1259.

https://doi.org/10.1182/blood.V120.21.1259.1259

Published: 2012

Journal Articles

Optimizing Lentiviral Transduction of Human Natural Killer Cells

Su Su, MD, PhD, Dawn M Betters, Ph.D, Muthalagu Ramanathan, MD, Keyvan Keyvanfar, BS, Aleah Smith, Xingmin Feng, PhD, Elissa Furutani, Mattias Carlsten, MD Ph.D, Andreas Lundqvist, PhD, Richard Childs, MD

Blood (2011) 118 (21): 4714.

https://doi.org/10.1182/blood.V118.21.4714.4714

Published: 2011

Journal Articles

Systemically Administered Hydrocortisone Exerts Differential Effects on B and T Lymphocytes and Natural Killer Cells in Healthy Donors

Matthew J. Olnes, MD, PhD, Angelique Biancotto, PhD, Ena Wang, M.D., Robert Reger, Shira Perl, MD, Howard Dickler, MD, J. Philip McCoy, PhD, Francesco Marincola, M.D., Richard Childs, MD, Neal S. Young, MD

Blood (2011) 118 (21): 2179.

https://doi.org/10.1182/blood.V118.21.2179.2179

Published: 2011

Journal Articles

Co-Infusion of Allogeneic Cord Blood with Haploidentical CD34+ Cells Improved Transplant Outcome for Patients with Severe Aplastic Anemia Undergoing Cord Blood Transplantation

Blood (2011) 118 (21): 654.

https://doi.org/10.1182/blood.V118.21.654.654

Published: 2011

Journal Articles

A Phase I Trial of Adoptively Transferred Ex-Vivo Expanded Autologous Natural Killer (NK) Cells Following Treatment with Bortezomib to Sensitize Tumors to NK Cell Cytotoxicity

Robert N Reger, Maria Berg, Andreas Lundqvist, PhD, Theresa Donohue, MHS, PA-C, Mattias Carlsten, MD Ph.D, Dawn M Betters, Ph.D, Lisa Cook, RN, BSN, Catalina Ramos, RN, BSN, Sophia Grasmeder, RN, BSN, OCN, Su Su, MD, PhD, David Stroncek, MD, Jeremy Pantin, MD, Keyvan Keyvanfar, BS, Cristian A. Carvallo, MD, Hahn Khuu, MD, Richard Childs, MD

Blood (2011) 118 (21): 1001.

https://doi.org/10.1182/blood.V118.21.1001.1001

Published: 2011

Journal Articles

Impact of Tyrosine Kinase Inhibitor (TKI) in Chronic Myeloid Leukemia (CML) Relapsing After T Cell Depleted Allogeneic Stem Cell Transplantation (SCT)

Sawa Ito, MD, Minoo Battiwalla, MD, MS, Eleftheria K. Koklanaris, BSN, Jeanine Superata, Richard Childs, MD, A. John Barrett, MD

Blood (2011) 118 (21): 2762.

https://doi.org/10.1182/blood.V118.21.2762.2762

Published: 2011

Journal Articles

Allogeneic Hematopoietic Cell Transplantation (HCT) for Neuroblastoma (NB): The CIBMTR Experience

Blood (2011) 118 (21): 3074.

https://doi.org/10.1182/blood.V118.21.3074.3074

Published: 2011

Journal Articles

A Phase II Trial of IPH2101 (anti-KIR mAb) in Smoldering Multiple Myeloma

Neha Korde, MD, Jane Trepel, Mattias Carlsten, MD Ph.D, Adriana Zingone, MD, PhD, Rene Costello, Mary Ann Yancey, RN, Marcia Mulquin, RN, Irina Maric, MD, Katherine Calvo, MD, PhD, Prashant Ramesh Tembhare, MD, Constance Yuan, MD, PhD, Maryalice Stetler-Stevenson, MD, PhD, Min-Jung Lee, MD, Sylvia Alarcon, George Carter, PA, Richard Childs, MD, Ola Landgren, MD, PhD

Blood (2011) 118 (21): 2944.

https://doi.org/10.1182/blood.V118.21.2944.2944

Published: 2011

Journal Articles

In Vitro Assessment of Tolerance and Rejection Occurring After Co-Transplantation of Allogeneic Umbilical Cord Blood and Haploidentical CD34+ Cells as Treatment for Severe Aplastic Anemia

Nicole J. Gormley, MD, Aleah Smith, Maria Berg, Lisa Cook, RN, BSN, Catalina Ramos, RN, Sophia Grasmeder, RN, BSN, OCN, Theresa Donohue, MHS, PA-C, Richard Childs, MD

Blood (2010) 116 (21): 2352.

https://doi.org/10.1182/blood.V116.21.2352.2352

Published: 2010

NARROW

High-Efficiency Lentiviral Genetic Modification of Primary Human Natural Killer Cells

Durable Remission of Refractory and Advanced Stage Mycosis Fungoides/Sezary Syndrome (MF/SS) Utilizing an "Outpatient" Alemtuzumab and Fludarabine-Based Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation (PBSCT)

Final Result of a Pilot Study Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Allo-Immunized Patients Receiving HLA Mismatched Platelets

A Novel Method to Study the in Vivo Trafficking and Homing of Adoptively Transferred NK Cells in Rhesus Macaques and Humans

Clinical-Grade mRNA Electroporation of NK Cells: A Novel and Highly Efficient Method to Genetically Reprogram Human NK Cells for Cancer Immunotherapy

Forced Fucosylation With ASC-101 Enhances The Binding Of Ex Vivo Expanded Human NK Cells To E-Selectin: A Novel Method To Improve The Homing Of Adoptively Transferred NK Cells To The Bone Marrow In Patients With Hematological Malignancies

The Unique Ontogeny Of Natural Killer Cells As Revealed By Genetic Barcoding In The Nonhuman Primate Model

Rhesus Macaque NK Cells Expanded Ex Vivo Undergo Similar Phenotypic and Functional Changes Observed With Expanded Human NK Cells Providing An Excellent Model To Optimize Adoptive NK Cell Transfer

Optimization of an Intra-Bone Hematopoietic Stem Cell Delivery Technique in a Swine Model.

Nicotinamide (NAM) Increases Surface Expression of CD62L On in Vitro Expanded NK Cells

High Dose Plerixafor Is Safe and Mobilizes Higher Numbers of CD34+ Cells Compared with Standard Dose Plerixafor

Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

Optimizing Lentiviral Transduction of Human Natural Killer Cells

Systemically Administered Hydrocortisone Exerts Differential Effects on B and T Lymphocytes and Natural Killer Cells in Healthy Donors

Co-Infusion of Allogeneic Cord Blood with Haploidentical CD34+ Cells Improved Transplant Outcome for Patients with Severe Aplastic Anemia Undergoing Cord Blood Transplantation

A Phase I Trial of Adoptively Transferred Ex-Vivo Expanded Autologous Natural Killer (NK) Cells Following Treatment with Bortezomib to Sensitize Tumors to NK Cell Cytotoxicity

Impact of Tyrosine Kinase Inhibitor (TKI) in Chronic Myeloid Leukemia (CML) Relapsing After T Cell Depleted Allogeneic Stem Cell Transplantation (SCT)

Allogeneic Hematopoietic Cell Transplantation (HCT) for Neuroblastoma (NB): The CIBMTR Experience

A Phase II Trial of IPH2101 (anti-KIR mAb) in Smoldering Multiple Myeloma

In Vitro Assessment of Tolerance and Rejection Occurring After Co-Transplantation of Allogeneic Umbilical Cord Blood and Haploidentical CD34+ Cells as Treatment for Severe Aplastic Anemia

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American Society of Hematology

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