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Journal Articles

Rocaglamide Selectively Eradicates Human Leukemia Stem Cells and Synergizes with Multiple Agents to Target AML Cells

Kevin P Callahan, PhD, Cheryl Corbett, Steven Jacob, Mohammad Minhajuddin, PhD, Eleni D Lagadinou, MD/PhD, Randall M Rossi, MS, Valerie Gross, Marlene Balys, Fred Hagen, PhD, Alison J Frontier, PhD, Craig T. Jordan, PhD

Blood (2012) 120 (21): 1338.

https://doi.org/10.1182/blood.V120.21.1338.1338

Published: 2012

Journal Articles

Bcl-2 Inhibitor ABT-263 Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Eleni D Lagadinou, MD/PhD, Alexander Sach, BS, Kevin P Callahan, PhD, Randall M. Rossi, MS, Sarah Neering, MS, Shanshan Pei, BS, Kristen O'Dwyer, MD, Jane L. Liesveld, MD, Paul S. Brookes, PhD, Michael W. Becker, MD, Craig T. Jordan, PhD

Blood (2012) 120 (21): 206.

https://doi.org/10.1182/blood.V120.21.206.206

Published: 2012

Journal Articles

Reactive Oxygen Species (ROS) Levels Define Functional Heterogeneity in Human Leukemia Stem Cells and Represent a Critical Parameter for Therapeutic Targeting

Eleni Lagadinou, MD/PhD, Kevin Callahan, PhD, Sarah J Neering, BS, ShanShan Pei, BS, Mohammad Minhajuddin, PhD, Randall M Rossi, MS, Valerie Grose, BS, Cheryl Corbett, Marlene Balys, BS, Paul Brookes, PhD, Craig T. Jordan, PhD

Blood (2011) 118 (21): 639.

https://doi.org/10.1182/blood.V118.21.639.639

Published: 2011

Journal Articles

Molecular Mechanisms of Parthenolide-Mediated Pro-Apoptotic Activity in Acute Myeloid Leukemia Cells

Mohammad Minhajuddin, PhD, Shanshan Pei, John M Ashton, Kevin Callahan, PhD, Eleni Lagadinou, MD/PhD, Marlene Balys, Cheryl Corbett, Sarah Neering, Randall M Rossi, MS, Craig T. Jordan, PhD

Blood (2011) 118 (21): 2463.

https://doi.org/10.1182/blood.V118.21.2463.2463

Published: 2011

Journal Articles

Troglitazone and Prochloroperazine Repositioned As An Anti-Leukemia Stem Cell Drug Combination Using Chemical Genomics-Based Prediction

Duane C Hassane, PhD, Jeanne P. De Leon, Cheryl Corbett, Randall M Rossi, MS, Wen Xie, MS, Craig T. Jordan, PhD, Monica L. Guzman, PhD

Blood (2011) 118 (21): 1885.

https://doi.org/10.1182/blood.V118.21.1885.1885

Published: 2011

Journal Articles

Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways

Duane C. Hassane, Siddhartha Sen, Mohammad Minhajuddin, Randall M. Rossi, Cheryl A. Corbett, Marlene Balys, Liping Wei, Peter A. Crooks, Monica L. Guzman, Craig T. Jordan

Blood (2010) 116 (26): 5983–5990.

https://doi.org/10.1182/blood-2010-04-278044

Published: 2010

Includes: Supplemental data

Journal Articles

Clonally Related B-NHL Populations and Cell Lines Harbor Subsets with Significant Phenotypic and Functional Heterogeneity.

Sherry A. Wuensch, Randall M. Rossi, Richard Burack, Paul G. Rothberg, Craig T. Jordan, Faith M Young

Blood (2009) 114 (22): 1699.

https://doi.org/10.1182/blood.V114.22.1699.1699

Published: 2009

Journal Articles

Heterogeneity in Phenotype, Functional Capacity, and Drug Sensitivity for Pediatric Acute Leukemia.

Christina M. Wiedl, DO, Terzah M. Horton, MD, PhD, Randall M Rossi, M.S., Sarah J Neering, M.S., Valerie Grose, B.S., Craig T. Jordan, PhD

Blood (2009) 114 (22): 2654.

https://doi.org/10.1182/blood.V114.22.2654.2654

Published: 2009

Journal Articles

Rational Combinations Including a Novel Syk Inhibitor, Fostamatinib Disodium (FosD) in Diffuse Large B Cell Lymphoma.

Randall M Rossi, Valerie Grose, Polly Pine, Richard I Fisher, MD, Craig T. Jordan, PhD, Jonathan W. Friedberg, MD

Blood (2009) 114 (22): 283.

https://doi.org/10.1182/blood.V114.22.283.283

Published: 2009

Journal Articles

Chemical Genomic Screening Reveals That PI3K/mTOR Inhibition Enhances Activity of the Anti-Leukemia Stem Cell Compound Parthenolide.

Duane Hassane, Ph.D., Siddhartha Sen, Cheryl A Corbett, Marlene Balys, Randall M Rossi, Peter A Crooks, PhD, Monica L. Guzman, PhD, Craig T. Jordan, PhD

Blood (2009) 114 (22): 388.

https://doi.org/10.1182/blood.V114.22.388.388

Published: 2009

Journal Articles

Inhibition of Human Lymphoma Cell Growth by the PKC-Beta Selective Inhibitor Enzastaurin (LY317615) in Combination with Multiple Therapeutic Agents.

Randall M Rossi, Marlene Balys, Dean Franklin, Valerie Grose, Richard I Fisher, Craig Jordan

Blood (2008) 112 (11): 1595.

https://doi.org/10.1182/blood.V112.11.1595.1595

Published: 2008

Journal Articles

The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19 ARF gene

Pin-Yi Wang, Fay Young, Chun-Yu Chen, Brett M. Stevens, Sarah J. Neering, Randall M. Rossi, Timothy Bushnell, Igor Kuzin, David Heinrich, Andrea Bottaro, Craig T. Jordan

Blood (2008) 112 (10): 4184–4192.

https://doi.org/10.1182/blood-2008-02-142190

Published: 2008

Includes: Supplemental data

Journal Articles

Protein kinase C–associated kinase is required for NF-κB signaling and survival in diffuse large B-cell lymphoma cells

Sang-Woo Kim, David W. Oleksyn, Randall M. Rossi, Craig T. Jordan, Ignacio Sanz, Luojing Chen, Jiyong Zhao

Blood (2008) 111 (3): 1644–1653.

https://doi.org/10.1182/blood-2007-05-088591

Published: 2008

Includes: Supplemental data

Journal Articles

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

Monica L. Guzman, Xiaojie Li, Cheryl A. Corbett, Randall M. Rossi, Timothy Bushnell, Jane L. Liesveld, Josée Hébert, Fay Young, Craig T. Jordan

Blood (2007) 110 (13): 4436–4444.

https://doi.org/10.1182/blood-2007-05-088815

Published: 2007

Includes: Supplemental data

Journal Articles

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

Monica L. Guzman, Randall M. Rossi, Sundar Neelakantan, Xiaojie Li, Cheryl A. Corbett, Duane C. Hassane, Michael W. Becker, John M. Bennett, Edmund Sullivan, Joshua L. Lachowicz, Andrew Vaughan, Christopher J. Sweeney, William Matthews, Martin Carroll, Jane L. Liesveld, Peter A. Crooks, Craig T. Jordan

Blood (2007) 110 (13): 4427–4435.

https://doi.org/10.1182/blood-2007-05-090621

Published: 2007

Includes: Supplemental data

Journal Articles

Leukemia stem cells in a genetically defined murine model of blast-crisis CML

Sarah J. Neering, Timothy Bushnell, Selcuk Sozer, John Ashton, Randall M. Rossi, Pin-Yi Wang, Deborah R. Bell, David Heinrich, Andrea Bottaro, Craig T. Jordan

Blood (2007) 110 (7): 2578–2585.

https://doi.org/10.1182/blood-2007-02-073031

Published: 2007

Includes: Supplemental data

Journal Articles

In Vivo Analyses of Leukemia Stem Cells in Genetically Defined Murine Models of Chronic and Blast Crisis CML.

Craig T. Jordan, PhD, Sarah J. Neering, MS, Pin-Yi Wang, BS, Randall M. Rossi, MS, Timothy Bushnell, PhD

Blood (2006) 108 (11): 236.

https://doi.org/10.1182/blood.V108.11.236.236

Published: 2006

Journal Articles

Rapid Loss of Membrane Integrity and Irreversible Commitment to Cell Death of Primary AML Stem Cells: A Novel Activity for 4-benzyl, 2-methyl,1,2,4-Thiadiazolidine,3,5 Dione (TDZD-8).

Monica L. Guzman, PhD, Xiaojie Li, BS, Cheryl Corbett, BS, Randall M. Rossi, MS, Timothy Bushnell, PhD, Craig T. Jordan, PhD

Blood (2006) 108 (11): 2535.

https://doi.org/10.1182/blood.V108.11.2535.2535

Published: 2006

Journal Articles

A Novel Orally Available Parthenolide Analog Selectively Eradicates AML Stem and Progenitor Cells.

Monica L. Guzman, PhD, Randall M. Rossi, MS, Xiaojie Li, BS, Cheryl Corbett, BS, Duane C. Hassane, PhD, Timothy Bushnell, PhD, Martin Carroll, MD, Edmund Sullivan, DVM, Sundar Neelakantan, PhD, Peter A. Crooks, PhD, Craig T. Jordan, PhD

Blood (2006) 108 (11): 237.

https://doi.org/10.1182/blood.V108.11.237.237

Published: 2006

Journal Articles

Modeling the Origins of Lymphoid Blast Crisis Via Expression of BCR/ABL in Hematopoietic Cells Mutated at the INK4a/ARF Locus.

Pin-Yi Wang, Fay Young, MD, Randall M. Rossi, MS, Timothy Bushnell, PhD, Craig T. Jordan, PhD

Blood (2005) 106 (11): 464.

https://doi.org/10.1182/blood.V106.11.464.464

Published: 2005

NARROW

Rocaglamide Selectively Eradicates Human Leukemia Stem Cells and Synergizes with Multiple Agents to Target AML Cells

Bcl-2 Inhibitor ABT-263 Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Reactive Oxygen Species (ROS) Levels Define Functional Heterogeneity in Human Leukemia Stem Cells and Represent a Critical Parameter for Therapeutic Targeting

Molecular Mechanisms of Parthenolide-Mediated Pro-Apoptotic Activity in Acute Myeloid Leukemia Cells

Troglitazone and Prochloroperazine Repositioned As An Anti-Leukemia Stem Cell Drug Combination Using Chemical Genomics-Based Prediction

Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways

Clonally Related B-NHL Populations and Cell Lines Harbor Subsets with Significant Phenotypic and Functional Heterogeneity.

Heterogeneity in Phenotype, Functional Capacity, and Drug Sensitivity for Pediatric Acute Leukemia.

Rational Combinations Including a Novel Syk Inhibitor, Fostamatinib Disodium (FosD) in Diffuse Large B Cell Lymphoma.

Chemical Genomic Screening Reveals That PI3K/mTOR Inhibition Enhances Activity of the Anti-Leukemia Stem Cell Compound Parthenolide.

Inhibition of Human Lymphoma Cell Growth by the PKC-Beta Selective Inhibitor Enzastaurin (LY317615) in Combination with Multiple Therapeutic Agents.

The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19 ARF gene

Protein kinase C–associated kinase is required for NF-κB signaling and survival in diffuse large B-cell lymphoma cells

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

Leukemia stem cells in a genetically defined murine model of blast-crisis CML

In Vivo Analyses of Leukemia Stem Cells in Genetically Defined Murine Models of Chronic and Blast Crisis CML.

Rapid Loss of Membrane Integrity and Irreversible Commitment to Cell Death of Primary AML Stem Cells: A Novel Activity for 4-benzyl, 2-methyl,1,2,4-Thiadiazolidine,3,5 Dione (TDZD-8).

A Novel Orally Available Parthenolide Analog Selectively Eradicates AML Stem and Progenitor Cells.

Modeling the Origins of Lymphoid Blast Crisis Via Expression of BCR/ABL in Hematopoietic Cells Mutated at the INK4a/ARF Locus.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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