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Journal Articles

A Subpopulation of Blasts with Attenuated p38 MAPK Response Is Seen in Virtually All AML Patients and AML Cell Lines and Is Defined By Cells with Augmented Lipid-Associated Anti-Oxidant Defense

Paul S. Hole, PhD, Sara Davies, MSc, Chinmay R Munje, BSc PhD, Sandra Kreuser, BSc, Robert K. Hills, MA MSc DPhil, Nader Omidvar, PhD, Steven Knapper, DM BMBCh, Alan K. Burnett, MDFRCP, Alex Tonks, BSc PhD, Richard L. Darley, BSc PhD

Blood (2014) 124 (21): 785.

https://doi.org/10.1182/blood.V124.21.785.785

Published: 2014

Journal Articles

Analysis of ROS-Responsive Genes in Mutant RAS Expressing Hematopoietic Progenitors Identifies the Glycolytic Pathway As a Major Target Promoting Both Proliferation and Survival

Goitseone Lucy Hopkins, BSc (Hons) MSc, Andrew J Robinson, BSc MRes, Paul S Hole, PhD, Richard L. Darley, BSc PhD, Alex Tonks, BSc PhD

Blood (2014) 124 (21): 2210.

https://doi.org/10.1182/blood.V124.21.2210.2210

Published: 2014

Journal Articles

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

Paul S. Hole, Joanna Zabkiewicz, Chinmay Munje, Zarabeth Newton, Lorna Pearn, Paul White, Nuria Marquez, Robert K. Hills, Alan K. Burnett, Alex Tonks, Richard L. Darley

Blood (2013) 122 (19): 3322–3330.

https://doi.org/10.1182/blood-2013-04-491944

Published: 2013

Includes: Supplemental data

Journal Articles

Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34 + hematopoietic progenitor cells

Paul S. Hole, Lorna Pearn, Amanda J. Tonks, Philip E. James, Alan K. Burnett, Richard L. Darley, Alex Tonks

Blood (2010) 115 (6): 1238–1246.

https://doi.org/10.1182/blood-2009-06-222869

Published: 2010

Includes: Supplemental data

Journal Articles

Ras Promotes Production of Reactive Oxygen Species in Normal Human CD34 + Cells: Role in Promoting Cell Survival and Protein Phosphorylation

Paul S Hole, BA, Lorna Pearn, Philip E James, PhD, Alan Burnett, MD, Richard L Darley, PhD, Alex Tonks, PhD

Blood (2008) 112 (11): 3797.

https://doi.org/10.1182/blood.V112.11.3797.3797

Published: 2008

NARROW

A Subpopulation of Blasts with Attenuated p38 MAPK Response Is Seen in Virtually All AML Patients and AML Cell Lines and Is Defined By Cells with Augmented Lipid-Associated Anti-Oxidant Defense

Analysis of ROS-Responsive Genes in Mutant RAS Expressing Hematopoietic Progenitors Identifies the Glycolytic Pathway As a Major Target Promoting Both Proliferation and Survival

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34 + hematopoietic progenitor cells

Ras Promotes Production of Reactive Oxygen Species in Normal Human CD34 + Cells: Role in Promoting Cell Survival and Protein Phosphorylation

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ASH Publications

American Society of Hematology

A Subpopulation of Blasts with Attenuated p38 MAPK Response Is Seen in Virtually All AML Patients and AML Cell Lines and Is Defined By Cells with Augmented Lipid-Associated Anti-Oxidant Defense

Analysis of ROS-Responsive Genes in Mutant RAS Expressing Hematopoietic Progenitors Identifies the Glycolytic Pathway As a Major Target Promoting Both Proliferation and Survival

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34 + hematopoietic progenitor cells

Ras Promotes Production of Reactive Oxygen Species in Normal Human CD34 + Cells: Role in Promoting Cell Survival and Protein Phosphorylation

Email alerts

ASH Publications

American Society of Hematology

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