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Journal Articles

Long-Term Effect of Ruxolitinib (RUX) in Inadequately Controlled Polycythemia Vera (PV) without Splenomegaly: 5-Year Results from the Phase 3 Response-2 Study

Francesco Passamonti, MD, Francesca Palandri, MD PhD, Guray Saydam, MD, Miklos Egyed, MD PhD, Jeannie Callum, MD FRCPC, Timothy Devos, MD, Serdar Sivgin, MD, Paola Guglielmelli, MD, Alessandro M. Vannucchi, MD, Evren Zor, MD, Geralyn Gilotti, MSc, Yifan Zhang, PhD, Martin Griesshammer, MD PhD

Blood (2020) 136 (Supplement 1): 40–41.

https://doi.org/10.1182/blood-2020-139281

Published: 2020

Journal Articles

The Final Analysis of Expand: A Phase 1b, Open-Label, Dose-Finding Study of Ruxolitinib (RUX) in Patients (pts) with Myelofibrosis (MF) and Low Platelet (PLT) Count (50 × 10 9 /L to < 100 × 10 9 /L) at Baseline

Paola Guglielmelli, MD, Jean-Jacques Kiladjian, MD PhD, Alessandro M. Vannucchi, MD, Ming-hui Duan, MD, Haitao Meng, MD PhD, Ling Pan, MD PhD, Guangsheng He, MD PhD, Srdan Verstovsek, MD PhD, Françoise Boyer-Perrard, MD, Fiorenza Barraco, MD, Dietger Niederwieser, MD PhD, Anna Marina Liberati, MD, Claire Harrison, DM, FRCP, FRCPath, Pantelia Roussou, MSc, Monika Wroclawska, MD, Kevin Majidi, Peter AW te Boekhorst, MD PhD, Heinz Gisslinger, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-137742

Published: 2020

Journal Articles

Validation of the International Prognostic Score for Thrombosis in Essential Thrombocythemia (IPSET) in Patients with Pre-Fibrotic Primary Myelofibrosis

Paola Guglielmelli, MD PhD, Alessandra Carobbio, BSc, Elisa Rumi, MD, Valerio De Stefano, MD, Lara Mannelli, MD, Francesco Mannelli, MD, Giada Rotunno, PhD, Giacomo Coltro, MD, Silvia Betti, MD PhD, Chiara Cavalloni, MD, Maria Chiara Finazzi, MD, Juergen Thiele, MD PhD, Mario Cazzola, MD, Alessandro M. Vannucchi, MD, Tiziano Barbui, MD

Blood (2019) 134 (Supplement_1): 1657.

https://doi.org/10.1182/blood-2019-124302

Published: 2019

Journal Articles

Final Analysis at 5 Years Follow up of Patients with MPN-Associated Splanchnic Vein Thrombosis Treated with Ruxolitinib in a Phase 2 Study

Chiara Paoli, PhD, Paola Guglielmelli, MD PhD, Francesco Mannelli, MD, Lara Mannelli, MD, Vittorio Rosti, MD, Maria Chiara Finazzi, MD, Elisa Rumi, MD, Marco Ruggeri, Alessandro Pancrazzi, PhD, Carmela Mannarelli, PhD, Guido Finazzi, MD, Maria Luisa Ferrari, BSc, Laura Lissandrini, BSc, Duccio Fantoni, RN, Giovanni Barosi, Mario Cazzola, MD, Tiziano Barbui, MD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 1662.

https://doi.org/10.1182/blood-2019-122837

Published: 2019

Journal Articles

Multi-Lineage Dysplasia Assessment By Immunophenotype in Myeloproliferative Neoplasms (MPN): Correlation with Disease' Variant, Clinical Features and Molecular Genetics

Francesco Mannelli, MD, Sara Bencini, Benedetta Peruzzi, Paola Guglielmelli, MD PhD, Annalisa Pacilli, PhD, Giada Rotunno, PhD, Francesca Gesullo, BSci, Blerina Jance, Marida Bonetti, Roberto Caporale, Francesco Annunziato, PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 1668.

https://doi.org/10.1182/blood-2019-125843

Published: 2019

Journal Articles

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Paola Guglielmelli, MD PhD, Niccolò Bartalucci, PhDBSc, Elisa Contini, PhD, Giada Rotunno, PhD, Annalisa Pacilli, PhD, Simone Romagnoli, BSc, Lara Mannelli, MD, Francesco Mannelli, MD, Giacomo Coltro, MD, Alessandro Pancrazzi, PhD, Valentina Ariu, BSci, Sara Fiaccabrino, Roberto Semeraro, Alberto Magi, PhD, Carmela Mannarelli, PhD, Francesca Gesullo, BSci, Chiara Paoli, PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 2968.

https://doi.org/10.1182/blood-2019-129094

Published: 2019

Journal Articles

Impact of Bone Marrow Fibrosis Grade in Post-Polycythemia Vera and Post-Essential Thrombocythemia Myelofibrosis. a Study of the Mysec Group

Blood (2019) 134 (Supplement_1): 2946.

https://doi.org/10.1182/blood-2019-124854

Published: 2019

Journal Articles

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Manjola Balliu, PhD, Laura Calabresi, PhD, Niccolò Bartalucci, PhDBSc, Laura Maggi, PhD, Francesco Annunziato, PhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 471.

https://doi.org/10.1182/blood-2019-123685

Published: 2019

Journal Articles

Adherence to Treatment in Myelofibrosis Patients: Preliminary Results from Italian Romei Observational Study

Paola Guglielmelli, MD PhD, Francesca Palandri, PhD MD, Carmine Selleri, MD, Daniela Cilloni, MD PhD, Francesco Mendicino, MD, Patrizio Mazza, MD, Domenico Pastore, MD PhD, Giuseppe A. Palumbo, MD, Sergio Siragusa, Prof, MD, Vincenzo Pavone, Stefana Impera, MD, Mara Morelli, MD, Francesco Passamonti, MD, Massimo Breccia, MD

Blood (2019) 134 (Supplement_1): 4179.

https://doi.org/10.1182/blood-2019-124730

Published: 2019

Journal Articles

Frequency of Thrombosis Is Higher in MPN Patients Who Develop Second Cancer Than in Controls

Valerio De Stefano, MD, Arianna Ghirardi, PhD, Arianna Masciulli, PhD, Alessandra Carobbio, BSc, Francesca Palandri, PhD MD, Nicola Vianelli, MD, Elena Rossi, MD PhD, Silvia Betti, MD PhD, Ambra Di Veroli, MD, Alessandra Iurlo, MD PhD, Daniele Cattaneo, MD, Guido Finazzi, MD, Massimiliano Bonifacio, MD, Luigi Scaffidi, MD, Andrea Patriarca, MD, Elisa Rumi, MD, Ilaria Carola Casetti, MD, Clemency Stephenson, MD, Paola Guglielmelli, MD PhD, Elena Maria Elli, MD, Miroslava Palova, MD, Davide Rapezzi, MD, Daniel Erez, MD, Montse Gomez, MD, Kai Wille, MD, Manuel Pérez-Encinas, MD, Francesca Lunghi, MD, Anna Angona, MD PhD, Maria Laura Fox, MD, Eloise Beggiato, MD, Giulia Benevolo, MD, Giuseppe Carli, MD, Rossella Rosaria Cacciola, MD, Mary Frances McMullin, MD FRCPath, FRCP, Alessia Tieghi, MD, Valle Recasens, MD, Monia Marchetti, MD, Martin Griesshammer, MD, Alberto Alvarez-Larrán, MD PhD, Alessandro M. Vannucchi, MD, Alessandro Rambaldi, MD PhD, Tiziano Barbui, MD

Blood (2019) 134 (Supplement_1): 4170.

https://doi.org/10.1182/blood-2019-127982

Published: 2019

Journal Articles

Impact of Disease Burden in Myelofibrosis Patients: A Sub Analysis from Italian Romei Observational Study

Francesca Palandri, PhD MD, Massimo Breccia, MD, Carmine Selleri, MD, Francesco Mendicino, MD, Giuseppe A. Palumbo, MD PhD, Elisabetta Abruzzese, MD, Anna Marina Liberati, Nicola Di Renzo, MD, Fabrizio Pane, MD, Mario Tiribelli, Robin Foà, MD, Elena Maria Elli, MD, Giovanni Caocci, MD, Mara Morelli, MD, Paola Guglielmelli, MD PhD, Francesco Passamonti, MD

Blood (2019) 134 (Supplement_1): 4188.

https://doi.org/10.1182/blood-2019-125778

Published: 2019

Journal Articles

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

Maria Zingariello, PhD, Vittorio Rosti, MD, Alessandro M. Vannucchi, MD, Paola Guglielmelli, MD PhD, Claudio Bardelli, PhD, Maria Mazzarini, Rosa Alba Rana, Giovanni Barosi, Anna Rita Rita Migliaccio, PhD

Blood (2019) 134 (Supplement_1): 4209.

https://doi.org/10.1182/blood-2019-123140

Published: 2019

Journal Articles

Large Genomic Alterations Occurring in the Transition from Chronic to Blast Phase of Chronic Myeloproliferative Neoplasms

Niccolò Bartalucci, PhD BSc, Alberto Magi, PhD, Elisa Contini, PhD, Davide Bolognini, PhD, Simone Romagnoli, BSc, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD

Blood (2018) 132 (Supplement 1): 3028.

https://doi.org/10.1182/blood-2018-99-113048

Published: 2018

Journal Articles

Solid Tumors in Post-Polycythemia Vera and Post-Essential Thrombocythemia Myelofibrosis: A Study on 2220 Patients

Blood (2018) 132 (Supplement 1): 3039.

https://doi.org/10.1182/blood-2018-99-115318

Published: 2018

Journal Articles

Mutations and Thrombosis in Essential Thrombocythemia and Polycythemia Vera: Mayo-Careggi Alliance Study

Paola Guglielmelli, MD PhD, Naseema Gangat, MBBS, Giacomo Coltro, MD, Terra L. Lasho, PhD, Giuseppe Gaetano Loscocco, MD, Christy Finke, BS, Benedetta Sordi, MD, Mythri Mudireddy, MBBS, Giada Rotunno, PhD, Natasha Szuber, MD, Annalisa Pacilli, PhD, Rangit Reddy Vallapureddy, MBBS, Maura Nicolosi, MD, Domenico Penna, MD, Curtis A. Hanson, MD, Rhett P. Ketterling, Animesh Pardanani, MBBS, PhD, Alessandro M. Vannucchi, MD, Ayalew Tefferi, MD

Blood (2018) 132 (Supplement 1): 3040.

https://doi.org/10.1182/blood-2018-99-110045

Published: 2018

Journal Articles

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Simona Salati, PhD, Elena Genovese, BSc, Zelia Prudente, BSc, PhD, Chiara Carretta, Niccolò Bartalucci, PhD BSc, Valentina Pennucci, PhD, Samantha Ruberti, BSc, PhD, Chiara Rossi, PharmD, Sebastiano Rontauroli, BSc, Carmela Mannarelli, PhD, Roberta Zini, BSc, PhD, Elisa Bianchi, BSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhD

Blood (2018) 132 (Supplement 1): 4332.

https://doi.org/10.1182/blood-2018-99-112550

Published: 2018

Journal Articles

Real-World Management of Myelofibrosis with Ruxolitinib: Initial Analysis of an Italian Observational Study (ROMEI)

Massimo Breccia, MD, Paola Guglielmelli, MD PhD, Alessandra Malato, MD, Francesco Mendicino, MD, Giuseppe A. Palumbo, MD, Carmine Selleri, MD, Daniela Cilloni, MD PhD, Patrizio Mazza, MD, Sergio Siragusa, MD Professor, Elisabetta Abruzzese, Roberto Latagliata, Monica Crugnola, MD, Domenico Pastore, MD PhD, Giorgia Micucci, MD, Giulia Benevolo, MD, Mara Morelli, MD, Francesca Palandri, PhD MD, Francesco Passamonti

Blood (2018) 132 (Supplement 1): 4312.

https://doi.org/10.1182/blood-2018-99-110198

Published: 2018

Journal Articles

Risk Factors for Secondary Cancer in a Case-Control Study on 1,259 Patients with Myeloproliferative Neoplasms

Tiziano Barbui, MD, Arianna Ghirardi, PhD, Arianna Masciulli, PhD, Alessandra Carobbio, MSc, Francesca Palandri, PhD MD, Nicola Vianelli, MD, Valerio De Stefano, MD, Silvia Betti, MD, Ambra Di Veroli, MD, Alessandra Iurlo, Daniele Cattaneo, MD, Federica Delaini, MSc, Massimiliano Bonifacio, MD, Luigi Scaffidi, MD, Andrea Patriarca, MD, Elisa Rumi, MD, Clemency Stephenson, MD, Paola Guglielmelli, MD PhD, Elena Maria Elli, MD, Palova Miroslava, MD, Laura Bertolotti, MSc, Daniel Erez, MD, Montse Gomez, MD, Kai Wille, MD, Manuel Pérez-Encinas, MD, Francesca Lunghi, Anna Angola Figueras, MD, Maria Laura Fox, MD, Eloise Beggiato, MD, Giulia Benevolo, MD, Giuseppe Carli, MD, Rossella Rosari Cacciola, Mary Frances McMullin, MD, Alessia Tieghi, MD, Valle Recanses Flores, MD, Monia Marchetti, Martin Griesshammer, MD PhD, Alberto Alvarez-Larran, MD, Alessandro M. Vannucchi, MD, Guido Finazzi, MD

Blood (2018) 132 (Supplement 1): 4279.

https://doi.org/10.1182/blood-2018-99-112387

Published: 2018

Journal Articles

Mutation-Enhanced International Prognostic Systems for Essential Thrombocythemia (MIPSS-ET) and Polycythemia Vera (MIPSS-PV)

Ayalew Tefferi, MD, Paola Guglielmelli, MD PhD, Terra L. Lasho, PhD, Giacomo Coltro, MD, Christy Finke, BS, Giuseppe Gaetano Loscocco, MD, Mythri Mudireddy, MBBS, Benedetta Sordi, MD, Natasha Szuber, MD, Giada Rotunno, PhD, Rangit Vallapureddy, MBBS, Annalisa Pacilli, PhD, Maura Nicolosi, MD, Domenico Penna, MD, Curtis A. Hanson, MD, Rhett P. Ketterling, Animesh Pardanani, MBBS, PhD, Naseema Gangat, MBBS, Alessandro M. Vannucchi, MD

Blood (2018) 132 (Supplement 1): 578.

https://doi.org/10.1182/blood-2018-99-109715

Published: 2018

Journal Articles

JAK2 V617F Variant Allele Frequency Identifies Patients with Polycythemia Vera (PV) at High Risk for Venous Thrombosis

Paola Guglielmelli, MD PhD, Giacomo Coltro, MD, Giuseppe Gaetano Loscocco, MD, Benedetta Sordi, MD, Francesco Mannelli, MD, Chiara Paoli, PhD, Ilaria Marone, PhD, Alessandro Pancrazzi, PhD, Francesca Gesullo, BSci, Carmela Mannarelli, PhD, Tiziano Barbui, MD, Alessandro M. Vannucchi, MD

Blood (2018) 132 (Supplement 1): 1776.

https://doi.org/10.1182/blood-2018-99-112287

Published: 2018

NARROW

Long-Term Effect of Ruxolitinib (RUX) in Inadequately Controlled Polycythemia Vera (PV) without Splenomegaly: 5-Year Results from the Phase 3 Response-2 Study

The Final Analysis of Expand: A Phase 1b, Open-Label, Dose-Finding Study of Ruxolitinib (RUX) in Patients (pts) with Myelofibrosis (MF) and Low Platelet (PLT) Count (50 × 10 9 /L to < 100 × 10 9 /L) at Baseline

Validation of the International Prognostic Score for Thrombosis in Essential Thrombocythemia (IPSET) in Patients with Pre-Fibrotic Primary Myelofibrosis

Final Analysis at 5 Years Follow up of Patients with MPN-Associated Splanchnic Vein Thrombosis Treated with Ruxolitinib in a Phase 2 Study

Multi-Lineage Dysplasia Assessment By Immunophenotype in Myeloproliferative Neoplasms (MPN): Correlation with Disease' Variant, Clinical Features and Molecular Genetics

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Impact of Bone Marrow Fibrosis Grade in Post-Polycythemia Vera and Post-Essential Thrombocythemia Myelofibrosis. a Study of the Mysec Group

Dysregulated IL-6/GP130/JAK Signaling in Calreticulin Mutated Myeloproliferative Neoplasms (MPN)

Adherence to Treatment in Myelofibrosis Patients: Preliminary Results from Italian Romei Observational Study

Frequency of Thrombosis Is Higher in MPN Patients Who Develop Second Cancer Than in Controls

Impact of Disease Burden in Myelofibrosis Patients: A Sub Analysis from Italian Romei Observational Study

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

Large Genomic Alterations Occurring in the Transition from Chronic to Blast Phase of Chronic Myeloproliferative Neoplasms

Solid Tumors in Post-Polycythemia Vera and Post-Essential Thrombocythemia Myelofibrosis: A Study on 2220 Patients

Mutations and Thrombosis in Essential Thrombocythemia and Polycythemia Vera: Mayo-Careggi Alliance Study

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Real-World Management of Myelofibrosis with Ruxolitinib: Initial Analysis of an Italian Observational Study (ROMEI)

Risk Factors for Secondary Cancer in a Case-Control Study on 1,259 Patients with Myeloproliferative Neoplasms

Mutation-Enhanced International Prognostic Systems for Essential Thrombocythemia (MIPSS-ET) and Polycythemia Vera (MIPSS-PV)

JAK2 V617F Variant Allele Frequency Identifies Patients with Polycythemia Vera (PV) at High Risk for Venous Thrombosis

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American Society of Hematology

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