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P. Clint Spiegel, Jr.
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Journal Articles

Cryoem Structures and Conformational Landscapes of Activated Blood Coagulation Factor VIII and the Intrinsic Tenase Complex

Kenneth C Childers, Omar Davulcu, Carmen Helena Coxon, Pete Lollar, Christopher B. Doering, P. Clint Spiegel, Jr.
Journal: Blood
Blood (2024) 144 (Supplement 1): 428.
https://doi.org/10.1182/blood-2024-211229
Published: 2024
Journal Articles

Cryo-EM Structure of Coagulation Factor VIII Bound to a Patient-Derived Anti-A2 Domain Antibody Inhibitor

Kenneth C Childers, Jordan Vaughan, John S. Lollar, Christopher B Doering, Carmen Helena Coxon, P. Clint Spiegel, Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 2598.
https://doi.org/10.1182/blood-2023-182304
Published: 2023
Journal Articles

Biophysical Characterization of the Thermodynamic Basis and Binding Orientation for Factor VIII Membrane Association

Nathan G Avery, Kenneth C Childers, Selena Lu, Patrick Korus, Justin McGlone, Mady Jacobs, Tera Richardson, Juliet McGill, Kayla Croney, Jordan Vaughan, James McCarty, P. Clint Spiegel, Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 1234.
https://doi.org/10.1182/blood-2023-182340
Published: 2023
Journal Articles

Structure of coagulation factor VIII bound to a patient-derived anti–C1 domain antibody inhibitor

Brief Report
Kenneth C. Childers, Nathan G. Avery, Kevin A. Estrada Alamo, Omar Davulcu, Rose Marie Haynes, Pete Lollar, Christopher B. Doering, Carmen H. Coxon, P. Clint Spiegel, Jr.
Journal: Blood
Blood (2023) 142 (2): 197–201.
https://doi.org/10.1182/blood.2023020181
Published: 2023
Includes: Supplemental data
Journal Articles

Shining a light on thrombin activation

P. Clint Spiegel, Jr
Journal: Blood
Blood (2022) 139 (24): 3451–3453.
https://doi.org/10.1182/blood.2022016537
Published: 2022
Journal Articles

VWF self-association requires tensile force

P. Clint Spiegel, Jr
Journal: Blood
Blood (2021) 138 (23): 2309–2310.
https://doi.org/10.1182/blood.2021013534
Published: 2021
Journal Articles

Structure of blood coagulation factor VIII in complex with an anti–C1 domain pathogenic antibody inhibitor

Brief Report
Joseph S. Gish, Lexi Jarvis, Kenneth C. Childers, Shaun C. Peters, Connor S. Garrels, Ian W. Smith, H. Trent Spencer, Christopher B. Doering, Pete Lollar, P. Clint Spiegel, Jr
Journal: Blood
Blood (2021) 137 (21): 2981–2986.
https://doi.org/10.1182/blood.2020008940
Published: 2021
Includes: Supplemental data
Journal Articles

Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes

Justin D. Walter, Rachel A. Werther, Caileen M. Brison, Rebecca K. Cragerud, John F. Healey, Shannon L. Meeks, Pete Lollar, P. Clint Spiegel, Jr
Journal: Blood
Blood (2013) 122 (26): 4270–4278.
https://doi.org/10.1182/blood-2013-08-519124
Published: 2013
Includes: Supplemental data
Journal Articles

Structural Studies Of The Factor VIII C2 Domain In a Ternary Complex With Two Inhibitory Antibodies Reveals Classical and Non-Classical Epitopes

Justin D Walter, M.S., Rachel A Werther, M.S., Caileen M Brison, B.S., John F. Healey, B.S., Shannon L. Meeks, MD, John (Pete) S. Lollar, III, MD, P. Clint Spiegel, Jr., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 2358.
https://doi.org/10.1182/blood.V122.21.2358.2358
Published: 2013