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Journal Articles

Combined Deficiency of Chromosome 7 Myeloid Tumor Suppressors Enhances Chemotherapy Resistance

Matthew R. M. Jotte, Tanner C. Martinez, Angela Stoddart, Molly K. Imgruet, Henna S. Nam, Bonnie Hu, Saira Khan, Ningfei An, Megan E. McNerney

Blood (2023) 142 (Supplement 1): 5689.

https://doi.org/10.1182/blood-2023-189308

Published: 2023

Journal Articles

Chromosome 7 Myeloid Tumor Suppressor Genes Cooperate in Chemotherapy Resistance

Matthew R.M. Jotte, Henna S. Nam, Bonnie Hu, Tanner C. Martinez, Saira Khan, Ningfei An, Angela Stoddart, Megan E. McNerney

Blood (2022) 140 (Supplement 1): 8720.

https://doi.org/10.1182/blood-2022-169602

Published: 2022

Journal Articles

CUX1 Deficiency Potentiates RAS Signaling to Drive Malignancy

Ningfei An, Molly K Imgruet, Saira Khan, Lia Jueng, Sandeep Gurbuxani, Megan E. McNerney

Blood (2021) 138 (Supplement 1): 1159.

https://doi.org/10.1182/blood-2021-148694

Published: 2021

Journal Articles

Loss of a 7q gene, CUX1 , disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms

Molly K. Imgruet, Julian Lutze, Ningfei An, Bonnie Hu, Saira Khan, Jeffrey Kurkewich, Tanner C. Martinez, Donald Wolfgeher, Sandeep K. Gurbuxani, Stephen J. Kron, Megan E. McNerney

Blood (2021) 138 (9): 790–805.

https://doi.org/10.1182/blood.2020009195

Published: 2021

Includes: Supplemental data

Journal Articles

Deficiency of CUX1, Encoded on 7q, Blocks the Normal HSC DNA Damage Response and Drives Highly Penetrant Therapy-Related Myeloid Neoplasms in Mice

Molly K Imgruet, BS, Ningfei An, PhD, Saira Khan, MS, Julian K Lutze, BS, Bonnie Hu, Stephen J. Kron, MD PhD, Sandeep Gurbuxani, MBBS, PhD, Megan E. McNerney, MD PhD

Blood (2019) 134 (Supplement_1): 641.

https://doi.org/10.1182/blood-2019-130717

Published: 2019

Journal Articles

Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS

Ningfei An, Saira Khan, Molly K. Imgruet, Sandeep K. Gurbuxani, Stephanie N. Konecki, Michael R. Burgess, Megan E. McNerney

Blood (2018) 131 (24): 2682–2697.

https://doi.org/10.1182/blood-2017-10-810028

Published: 2018

Includes: Supplemental data

Journal Articles

Deficiency of Cux1 , Encoded on Human Chromosome 7q, Causes Aberrant Hematopoietic Stem Cell Function and Spontaneous Myeloproliferative Disease in Mice

Ningfei An, PhD, Saira Khan, Molly Imgruet, Sandeep Gurbuxani, MBBS, PhD, Michael R. Burgess, MD PhD, Megan E. McNerney, MD PhD

Blood (2017) 130 (Supplement 1): 789.

https://doi.org/10.1182/blood.V130.Suppl_1.789.789

Published: 2017

Journal Articles

Enhancer-Promoter Looping Deciphers Dosage of the Haploinsufficient Transcription Factor, CUX1

Robert K Arthur, PhD, Ningfei An, PhD, Saira Kahn, Megan E. McNerney, MD PhD

Blood (2016) 128 (22): 2700.

https://doi.org/10.1182/blood.V128.22.2700.2700

Published: 2016

Journal Articles

Therapeutic Targeting of PIM Protein Kinases in a Subset of T-Cell Acute Lymphoblastic Leukemia

Sathish Kumar Reddy Padi, PhD, Libia A Luevano, ND, Ningfei An, PhD, Ritu Pandey, PhD, Neha Singh, PhD, Jin H Song, PhD, Jon C. Aster, MD PhD, Xue-Zhong Yu, PhD, Shikhar Mehrotra, PhD, Andrew S Kraft, MD

Blood (2016) 128 (22): 2742.

https://doi.org/10.1182/blood.V128.22.2742.2742

Published: 2016

Journal Articles

Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma

Jagadish Kummetha Venkata, Ningfei An, Robert Stuart, Luciano J. Costa, Houjian Cai, Woodrow Coker, Jin H. Song, Kiwana Gibbs, Terri Matson, Elizabeth Garrett-Mayer, Zhuang Wan, Besim Ogretmen, Charles Smith, Yubin Kang

Blood (2014) 124 (12): 1915–1925.

https://doi.org/10.1182/blood-2014-03-559385

Published: 2014

Includes: Supplemental data

Journal Articles

Sphingolipids As a Novel Target For The Treatment Of Multiple Myeloma

Jagadish Kummetha Venkata, PhD, Robert K Stuart, Luciano J Costa, MD, PhD, Ningfei An, PhD, Houjian Cai, PhD, Woodrow J. Coker, MD, Jin Song, PhD, Kiwana Gibbs, Terri Matson, Charles D Smith, Yubin Kang, MD.

Blood (2013) 122 (21): 3163.

https://doi.org/10.1182/blood.V122.21.3163.3163

Published: 2013

Journal Articles

Pim1 Serine/Threonine Kinase Regulates the Number and Functions of Murine Hematopoietic Stem Cells.

Ningfei An, PhD, Yingwei Lin, MD., PhD., Sandeep Mahajan, Ph.D., Yong Wang, MD, PhD, Andrew Kraft, MD, Yubin Kang, MD.

Blood (2012) 120 (21): 2303.

https://doi.org/10.1182/blood.V120.21.2303.2303

Published: 2012

Journal Articles

Potential Use of Sphingosine Kinase-2 Selective Inhibitors for the Treatment of Multiple Myeloma

Ningfei An, PhD, Yeong-Bin Im, Peng Gao, Luciano J Costa, MD, PhD, Robert K Stuart, MD, Charles Smith, PhD, Yubin Kang, MD.

Blood (2011) 118 (21): 5105.

https://doi.org/10.1182/blood.V118.21.5105.5105

Published: 2011

Journal Articles

Characterization of Pim Protein Kinases and Evaluation of Small Molecule Inhibitors in Multiple Myeloma

Ningfei An, PhD, Yeong-Bin Im, Yingwei Lin, MD., PhD., Cristina Gasparetto, MD, Luciano J Costa, MD, PhD, Robert K Stuart, MD, Charles Smith, PhD, Andrew Kraft, MD, Yubin Kang, MD.

Blood (2011) 118 (21): 2909.

https://doi.org/10.1182/blood.V118.21.2909.2909

Published: 2011

Journal Articles

A Novel Role of Pim Serine/Threonine Kinases in Hematopoiesis: Pim 1 Kinase Increases Hematopoietic Stem Cell Population

Yingwei Lin, MD., PhD., Ningfei An, PhD., Angen Liu, PhD., Michael B. Lilly, MD, Andrew Kraft, MD, Yubin Kang, MD.

Blood (2011) 118 (21): 561.

https://doi.org/10.1182/blood.V118.21.561.561

Published: 2011

Journal Articles

Regulation and Functional Role of Beta2-Adrenergic Receptor in Acute Myelogenous Leukemia

Ningfei An, PhD, Yeong-Bin Im, Amr Abdallah Moh'D Qudeimat, MD, Luciano J Costa, MD, PhD, Robert K Stuart, MD, Yubin Kang, MD.

Blood (2011) 118 (21): 2563.

https://doi.org/10.1182/blood.V118.21.2563.2563

Published: 2011

Journal Articles

Hematopoietic Stem Cells Repair Ionizing Radiation-Induced DNA Double Strand Breaks in a Cell Cycle-Dependent Manner.

Senthil Kumar Pazhanisamy, PhD, Ningfei An, PhD, Yong Wang, MD, PhD, Daohong Zhou, MD

Blood (2009) 114 (22): 3241.

https://doi.org/10.1182/blood.V114.22.3241.3241

Published: 2009

NARROW

Combined Deficiency of Chromosome 7 Myeloid Tumor Suppressors Enhances Chemotherapy Resistance

Chromosome 7 Myeloid Tumor Suppressor Genes Cooperate in Chemotherapy Resistance

CUX1 Deficiency Potentiates RAS Signaling to Drive Malignancy

Loss of a 7q gene, CUX1 , disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms

Deficiency of CUX1, Encoded on 7q, Blocks the Normal HSC DNA Damage Response and Drives Highly Penetrant Therapy-Related Myeloid Neoplasms in Mice

Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS

Deficiency of Cux1 , Encoded on Human Chromosome 7q, Causes Aberrant Hematopoietic Stem Cell Function and Spontaneous Myeloproliferative Disease in Mice

Enhancer-Promoter Looping Deciphers Dosage of the Haploinsufficient Transcription Factor, CUX1

Therapeutic Targeting of PIM Protein Kinases in a Subset of T-Cell Acute Lymphoblastic Leukemia

Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma

Sphingolipids As a Novel Target For The Treatment Of Multiple Myeloma

Pim1 Serine/Threonine Kinase Regulates the Number and Functions of Murine Hematopoietic Stem Cells.

Potential Use of Sphingosine Kinase-2 Selective Inhibitors for the Treatment of Multiple Myeloma

Characterization of Pim Protein Kinases and Evaluation of Small Molecule Inhibitors in Multiple Myeloma

A Novel Role of Pim Serine/Threonine Kinases in Hematopoiesis: Pim 1 Kinase Increases Hematopoietic Stem Cell Population

Regulation and Functional Role of Beta2-Adrenergic Receptor in Acute Myelogenous Leukemia

Hematopoietic Stem Cells Repair Ionizing Radiation-Induced DNA Double Strand Breaks in a Cell Cycle-Dependent Manner.

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American Society of Hematology

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American Society of Hematology

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